Pharmacology - Publications

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Author Title Date Place of Publication Research Group Co-Authors
Breckenridge AM Delta Steering Committee (A. Breckenridge, Chairman). Delta 1996 University of Liverpool Pharmacology of HIV Disease Aber V
Aboulker J-P
Babiker AG
Taylor C.W. Lateral inhibition of inositol 1,4,5-trisphosphate receptors by cytosolic Ca2+. 1999 University of Cambridge   Adkins, C.E.
Hoffman R Synthesis of sulphated acrylic polymers and their evaluation as inhibitors of basic fibroblast growth factor dependent cell growth 2000 University of Hertfordshire   Adnett JB
Hay JN
Niederst C
Perretti M Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse. 1996 Queen Mary, University of London Biochemical Pharmacology Ahluwalia A
Coker SJ Potential interactions between iloprost and SIN-1 on platelet aggregation and myocardial infarct size 1999 University of Liverpool Tropical Pharmacology Aitchison KA
Dickenson A.H. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. 1999 University College London Neuropharmacology and neuroscience Akopian, A N.
Souslova, V.
England, S.
Sellers L.A. Receptor isoforms mediate opposing proliferative effects through Gbg-activated p38 or Akt pathways. 2000 University of Cambridge   Alderton, F.
Carruthers, A.M.
Schindler, M.
Feniuk W. Differential effects of somatostatin and angiopeptin on cell proliferation. 1998 University of Cambridge   Alderton, F.
Lauder, H.
Fan, T.P.D.
Perrett D Optimised separation of endogenous urinary components using cyclodextrin-modified micellar electrokinetic capillary chromatography [In Process Citation] 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Alfazema LN
Howells S
Pirmohamed M Association analysis of drug metabolising enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole 2000 University of Liverpool Drug Safety Alfirevic A
Vilar J
Stalford A
Winyard P G Activation of NF-kappaB in human osteoblasts by stimulators of bone resorption. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Ali NN
Gilston V
Yaqoob M T Arachidonic acid protects against hypoxic injury in rat proximal tubules. 1996 Queen Mary, University of London Experimental Medicine and Nephrology Alkhunaizi AM
Edelstein CL
Gengaro PE
Getting S J Natural and synthetic agonists of the melanocortin receptor type 3 possess anti inflammatory properties. 2000 Queen Mary, University of London Biochemical Pharmacology Allcock GH
Flower RJ
Perretti M
Yaqoob M T Inhibition of CFU-E colony formation in uremic patients with inflammatory disease: role of IFN-gamma and TNF-alpha [see comments] 1999 Queen Mary, University of London Experimental Medicine and Nephrology Allen DA
Breen C
Macdougall
Brown D.A. Detection and modulation of acetylcholine release from neurites of rat cultured basal forebrain cells 1996 University College London Neuropharmacology and neuroscience Allen, T.G.J.
Kelly JS Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis 2000 University of Edinburgh Neuropharmacology Allsopp TE
McLuckie J
Kerr LE
Edwardson J.M. The secretory granule protein syncollin binds to syntaxin in a Ca2+-sensitive manner. 1997 University of Cambridge   An, S.
Jahn, R.
Edwardson J.M. Analysis of the association of syncollin with the membrane of the pancreatic zymogen granule. 2000 University of Cambridge   An, S.J.
Hansen, N.J.
Hodel, A.
Wyllie DJA Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors 1998 University of Edinburgh Neuropharmacology Anson LC
Chen PE
Wyllie DJA
Wyllie DJA Single-channel analysis of a NMDA receptor possessing a mutation in the region of the glutamate binding site 2000 University of Edinburgh Neuropharmacology Anson LC
Schoepfer R
Colquhoun D
Schoepfer R. Identification of amino acid residues of the NR2A subunit which control glutamate potency in recombinant NR1/NR2A NMDA receptors. 1998 University College London Receptors, ion channels and transduction Anson, L. C.
Chen, P. E.
Wyllie, D. J. A.
Schoepfer R. Single-channel analysis of a NMDA receptor possessing a mutation in the region of the glutamate binding site. 2000 University College London Receptors, ion channels and transduction Anson, L. C.
Colquhoun, D.
Wyllie, D. J. A
Colquhoun D. Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. 1998 University College London Receptors, ion channels and transduction Anson, L. C.
Chen, P. E.
Wyllie, D. J. A.
Antoni FA Ca2+/calcineurin-inhibited adenylyl cyclase highly abundant in forebrain regions important for learning and memory 1998 University of Edinburgh Neural Plasticity Antoni FA
Palkovits M
Simpson J
Antoni FA Molecular diversity of cyclic AMP signalling 2000 University of Edinburgh Neural Plasticity Antoni FA
Hemming K A thiazine-S-oxide, Staudinger/Aza-Wittig based synthesis of benzodiazepines and benzothiadiazeoines 2000 University of Hertfordshire   Anwar B
Grimsey P
Krajniewski M
Colville-Nash P R The role of vascular endothelial growth factor in a murine chronic granulomatous tissue air pouch model of angiogenesis. 1996 Queen Mary, University of London Biochemical Pharmacology Appleton I
Brown NJ
Willis D
Timmis A D Frequency and prognostic implications of conduction defects in acute myocardial infarction since the introduction of thrombolytic therapy. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Archbold RA
Sayer JW
Ray S
Grootveld M In vivo absorption, metabolism, and urinary excretion of alpha,beta-unsaturated aldehydes in experimental animals. Relevance to the development of cardiovascular diseases by the dietary ingestion of thermally stressed polyunsaturate-rich culinary oils. 1998 Queen Mary, University of London Pharmaceutical Bioanalysis Atherton MD
Sheerin AN
Hawkes J
Henderson R.M. A cell-free system for regulated exocytosis on PC12 cells. 2000 University of Cambridge   Avery, J.
Ellis, D.J.
Lang, T.
Breckenridge AM Quattro Steering Committee (A. Breckenridge, Chairman). A randomised trial comparing regimens of four reverse transcriptase inhibitors given together or cyclically in HIV-1 Infection 1999 University of Liverpool Pharmacology of HIV Disease Babiker A
Back DJ
Blatchford N
Haycox AR Clinical guidelines 1999 University of Liverpool Prescribing Research Group Bagust A
Walley T
Molleman A Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption 1998 University of Hertfordshire   Bailey C P
Little H J
Molleman A Chronic ethanol administration alters neuronal activity in VTA neurones after cessation of withdrawal hyperexcitability 1998 University of Hertfordshire   Bailey C P
Manley S J
Watson
Waring M.J. Demethylation of thymine residues affects DNA cleavage by endonucleases but not sequence recognition by drugs. 1999 University of Cambridge   Bailly, C.
Crow, S.
Minnock, A.
Vane J Cyclooxygenases 1 and 2. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Bakhle YS
Botting RM
Timmis A D Magnitude and consequences of error in coronary angiography interpretation (the ACRE study) [In Process Citation] 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Banerjee S
Crook AM
Dawson JR
Dickenson A.H. Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors. 1998 University College London Neuropharmacology and neuroscience Bannon, A W
Decker, M. W.
Holladay, M. W.
Corder R Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. 1999 Queen Mary, University of London Experimental Therapeutics Barker DM
Corder R The expression of endothelin-1 and endothelin-converting enzyme-1 are independently regulated in bovine aortic endothelial cells. 1999 Queen Mary, University of London Experimental Therapeutics Barker S
DAVIES N.W. Kinetic analysis of the inhibitory effect of glibenclamide on KATP channels of mammalian skeletal muscle 1997 University of Leicester   Barrett-Jolley, R.
DART C. Direct block of native and cloned (Kir2.1) inward rectifier K+ channels by chloroethylclonidine 1999 University of Leicester   Barrett-Jolley, R.
Standen N.B.
Garthwaite J. Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway. 1997 University College London Neuropharmacology and neuroscience Batchelor, A. M.
Coker SJ Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes 2000 University of Liverpool Tropical Pharmacology Batey AJ
Lightbown ID
Diaz ME
Coker SJ Comparison of the acute cardiotoxicity of the antimalarial drug halofantrine in vitro and in vivo in anaesthetized guinea pigs 1997 University of Liverpool Tropical Pharmacology Batey AJ
Lightbown ID
Lambert JP
Harmar AJ Presence of multiple functional polyadenylation signals and a single nucleotide polymorphism in the 3 untranslated region of the human serotonin transporter gene,Battersby S,Ogilvie AD,Blackwood DHR,5,Journal of Neurochemistry,72,1384-1388, 1999 University of Edinburgh Neuropharmacology Battersby S
Ogilvie AD
Blackwood DHR
Edwards IG Assessment of the effect of malaria infection on hepatic clearance of dihydroartemisinin using rat liver perfusions and microsomes 1998 University of Liverpool Tropical Pharmacology Batty KT
Ilett KF
Powell SM
Kelly EP Somatostatin receptor desensitization in NG108-15 cells: a consequence of receptor sequestration? 1998 University of Bristol   Beaumont,VL
Hepworth,MB
Luty,JS
Henderson G Somatostatin receptor desensitization in NG108-15 cells: a consequence of receptor sequestration? 1998 University of Bristol   Beaumont,VL
Hepworth,MB
Luty,JS
Molleman A CB1 cannabinoid receptor-mediated activation of K+ current in DDT1 MF-2 cells is entirely dependent on the presence of extracellular Ca2+ 1999 University of Hertfordshire   Begg M
Nelemans SA
Garthwaite J. Rapid desensitization of the nitric oxide receptor, soluble guanylyl cyclase, underlies diversity of cellular cGMP responses. 2000 University College London Neuropharmacology and neuroscience Bellamy, T.C.
Wood, J.
Goodwin, D.A.
Jenkinson D.H. Differences in the actions of some blockers of the calcium-activated potassium permeability in mammalian red cells. 1999 University College London Receptors, ion channels and transduction Benton, D. C. H.
Roxburgh, C. J.
Ganellin, C. R.
Gould D J A novel doxycycline inducible autoregulatory plasmid which displays 'on'/'off' regulation suited to gene therapy applications. 2000 Queen Mary, University of London Bone and Joint Research Unit Berenstein M
Dreja H
Ledda F
SOMOGYI P Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus 2000 University of Oxford Neuroscience Bergles, D.E.
Roberts, J.D.B.
Jahr, C.E.
WATSON SP Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation 2000 University of Oxford Integrative Biology Berlanga, O.
Bobe, R.
Becker, M.
Carter T.D. Potency and kinetics of nitric oxide-mediated vascular smooth muscle relaxation determined with flash photolysis of ruthenium nitrosyl chlorides. 1997 University College London Receptors, ion channels and transduction Bettache, N.
Ogden, D.C.
Hemming K A one-pot Aza-Wittig based solution and polymer supported route to amines 2000 University of Hertfordshire   Bevan MJ
Loukou C
Patel SD
Humphrey P.P.A. Acute nociception mediated by hindpaw P2X receptor activation in the rat. 1997 University of Cambridge   Bland-Ward, P.A.
EMPTAGE NJ Fluorescent imaging of synaptic transmission at single synapses in the central nervous system 1999 University of Oxford Neuroscience Bliss, T.
Fine, A.
EMPTAGE NJ Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines 1999 University of Oxford Neuroscience Bliss, T.V.P.
Fine, A.
WILLARS G.B. Pivotal role for the cytoplasmic carboxyl-terminal tail of a nonmammalian gonadotropin-releasing hormone receptor in cell surface expression, ligand binding, and receptor phosphorylation and internalization 1999 University of Leicester   Blomenroehr, M.
Heding A.
Sellar, R.
van Veen H.W. Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane. 1996 University of Cambridge   Bolhuis, H.
Molenaar, D.
Poolman, B.
La M Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase. 1998 Queen Mary, University of London Biochemical Pharmacology Bommel HM
Reif A
Frohlich LG
Park BK Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of a-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts 2000 University of Liverpool Drug Safety Boocock DJ
Maggs JL
Brown K
Ramage A.G. Involvement of central 5-HT1A receptors in the reflex activation of pulmonary vagal motoneurones by inhaled capsaicin in anaesthetized cats. 1996 University College London Neuropharmacology and neuroscience Bootle, D. J.
Adcock, J. J.
Vane J Anti-inflammatory drugs and their mechanism of action. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Botting RM
White R Human urotensin-II is an endothelium-dependent vasodilator in rat small arteries. 2000 University of Cambridge   Bottrill, F.E.
Douglas, S.A.
Hiley, C.R.
POMPEO F Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1-phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activity and 2000 University of Oxford Pharmacogenetics + Toxicology Bourne, Y.
van Heijenoort, J.
Fassy, F.
Thiemermann C Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle. 1997 Queen Mary, University of London Experimental Medicine and Nephrology Bowes J
Myint FP
Vane JR
Garthwaite J. Tyrosine kinase is required for long term depression in the cerebellum. 1996 University College London Neuropharmacology and neuroscience Boxall, A.
Lancaster, B.
Fan T.P.D. Expression of angiogenic factor thymidine phosphorylase and angiogenesis in human atherosclerosis. 2000 University of Cambridge   Boyle, J.J.
Wilson, B.
Bicknell, R.
Grant SGN A role for the Ras signalling pathway in synaptic transmission and long-term memory 1997 University of Edinburgh Neural Plasticity Brambilla R
Gnesutta N
Minichiello L
Caulfield M J Evaluation of the Angiotensinogen Locus in Human Essential Hypertension: A European Study. 1998 Queen Mary, University of London Clinical Pharmacology Brand E
Chatelain N
Keavney B
Ward SA 4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake 1996 University of Liverpool Tropical Pharmacology Bray PG
Hawley SR
Ward SA Access to heamatin: the basis of chloroquine resistance 1998 University of Liverpool Tropical Pharmacology Bray PG
Mungthin M
Ridley RG
Ward SA Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum 1999 University of Liverpool Tropical Pharmacology Bray PG
Janneh O
Raynes KJ
Ward SA Physicochemical properties correlated with drug resistance and its reversal in Plasmodium falciparum 1996 University of Liverpool Tropical Pharmacology Bray PG
Hawley SR
MacCallum P K Minimum effective intensity of oral anticoagulant therapy in primary prevention of coronary heart disease. 2000 Queen Mary, University of London Experimental Therapeutics Brennan PJ
Meade TW
Whelan CJ Reactive oxygen species generation and histamine release by activated mast cells: modulation by nitric oxide synthase inhibition 1999 University of Hertfordshire   Brooks A C
Purcell W M
Molleman A Reactive oxygen species generation by non-immunological mast cell activation: modulation by the synthetic cannabinoid CP55,940 1999 University of Hertfordshire   Brooks A C
Gustafsson F
Whelan C J
Coleman JW Presentation of IFN-g to nitric oxide oxide-producing cells : a novel function for mast cells 2000 University of Liverpool Drug Safety Brooks B
Briggs DM
Eastmond NC
POMPEO F Crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily 1999 University of Oxford Pharmacogenetics + Toxicology Brown, K.
Dixon, S.
Mengin-Lecreulx, D.
Roberts PJ Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures 1996 University of Bristol   Bruno,V
Copani,A
Bonanno,L
Jacobs M. Oxidized low-density lipoproteins inhibit endothelium-dependent relaxations in isolated large and small rabbit coronary arteries. 1996 University College London Receptors, ion channels and transduction Buckley, C.
Bund, S.J.
McTaggart, F.
TOBIN A.B. Activation of the mitogen-activated protein kinase pathway by a Gq/11 coupled muscarinic receptor is independent of receptor internalisation 1999 University of Leicester   Budd D.C.
Rae A.
TOBIN A.B. Cross-talk between m3-muscarinic and beta2-adrenergic receptors at the level of receptor phosphorylation and desensitisation 1999 University of Leicester   Budd D.C.
Challiss R.A.J.
Young K.W.
TOBIN A.B. Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha 2000 University of Leicester   Budd D.C.
McDonald J.E.
Humphrey P.P.A. Blockade of human P2X7 receptor function with a monoclonal antibody. 1998 University of Cambridge   Buell, G.
Chessell, I.P.
Michel, A.D.
GALIONE A Two neuropeptides recruit different messenger pathways to envoke Ca2+ signals in the same cell 2000 University of Oxford Integrative Biology Burdakov, D.
Rang H.P. Bradyzide, a potent non-peptide B(2) bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesia. 2000 University College London Neuropharmacology and neuroscience Burgess, G. M.
Perkins, M. N.
Campbell, E. A.
Sihra T.S. A modulatory role for protein phosphatase 2B (calcineurin) in the regulation of Ca 2000 University College London Neuropharmacology and neuroscience Burley, J. R.
Marshall I. The role of diacylglycerol and activation of protein kinase C in the alpha 1A-adrenoceptor-mediated contraction to noradrenaline of the rat isolated epididymal vas deferens. 1996 University College London Receptors, ion channels and transduction Burt, R. P.
Chapple, C. R.
Marshall I. Alpha1A-adrenoceptor mediated contraction of rat prostatic vas deferens and the involvement of ryanodine stores and Ca 1998 University College London Receptors, ion channels and transduction Burt, R. P.
Chapple, C. R.
Marshall I. Different subtypes of alpha1A-adrenoceptor mediating contraction of rat epididymal vas deferens, rat hepatic portal vein and human prostate distinguished by the antagonist RS 17053 1996 University College London Receptors, ion channels and transduction Burt, R. P.
Green, G. M.
Hussain, M. B.
Ferguson D.R. Activation of epithelial Na+ channel activity in the rabbit urinary bladder by cAMP. 2000 University of Cambridge   Burton, T.J.
Elneil, S.
Nelson, C.P.
Sharkey J Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism 1997 University of Edinburgh Neuropharmacology Butcher SP
Henshall DC
Teramura Y
Waring M.J. The exocyclic groups of DNA modulate the affinity and positioning of the histone octamer. 1998 University of Cambridge   Buttinelli, M.
Minnock, A.
Panetta, G.
CAVIERES J.D. K+ induces an acid-labile phosphoenzyme (or an occluded Pi form) in Na,K-ATPase 1997 University of Leicester   Buxbaum, E.
Ward, D.G.
Walton, T. J. H.
van Veen H.W. A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. 1998 University of Cambridge   Callaghan, R.
Soceneantu, L.
Sardini, A.
Jenkinson D.H. Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca 2000 University College London Receptors, ion channels and transduction Campos Rosa. J.
Galanakis, D.
Piergentili, A.
Thomas P. Real-time studies of zymogen granule exocytosis in intact rat pancreatic acinar cells. 2000 University of Cambridge   Campos-Toimil, M.
Edwardson, J.M.
Goulding N J Increased apoptosis in U937 cells over-expressing lipocortin 1 (annexin I) [In Process Citation] 2000 Queen Mary, University of London Biochemical Pharmacology Canaider S
Solito E
de Coupade C
GALIONE A Co-ordination of agonist-induced calcium signalling patterns by NAADP in pancreatic acinar cells 1999 University of Oxford Integrative Biology Cancela, J.M.
Churchill, G.C.
Dolphin A.C. Identification of residues in the N terminus of alpha1B critical for inhibition of the voltage-dependent calcium channel by G betagamma. 1999 University College London Neuropharmacology and neuroscience Canti, C.
Page, K. M.
Stephens G. J.
Genazzani A.A. Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons 1999 University of Cambridge   Carafoli, E.
Guerini, D.
Born G V R Increase by adrenaline or angiotensin II of the accumulation of low density lipoprotein and fibrinogen by aortic walls in unrestrained conscious rats. 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Cardona-Sanclemente LE
Dickenson A.H. Unaltered peripheral excitatory actions of nociceptin contrast with enhanced spinal inhibitory effects after carrageenan inflammation: an electrophysiological study in the rat. 2000 University College London Neuropharmacology and neuroscience Carpenter, K
Vithlani, M.
NAHORSKI S.R. Enhanced type 1alpha metabotropic glutamate receptor-stimulated phosphoinositide signalling after pertussis toxin treatment 1997 University of Leicester   Carruthers A.M.
Challiss R.A.J.
Mistry R.
Humphrey P.P.A. Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO-K1 cells and involvement of Gas proteins. 1999 University of Cambridge   Carruthers, A.M.
Warner, A.J.
Michel, A.D.
Morton A.J. Characterisation of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. 1999 University of Cambridge   Carter, R.J.
Lione, L.A.
Humby, T.
O'Byrne S Genetics of hypertension. Therapeutic implications. 1998 Queen Mary, University of London Clinical Pharmacology Caulfield M
Whittle B J Potentiation of cytokine induced iNOS expression in the human intestinal epithelial cell line, DLD-1, by cyclic AMP. 1999 Queen Mary, University of London Experimental Therapeutics Cavicchi M
Whittle B J Regulation of induction of nitric oxide synthase and the inhibitory actions of dexamethasone in the human intestinal epithelial cell line, Caco-2: influence of cell differentiation. 1999 Queen Mary, University of London Experimental Therapeutics Cavicchi M
McNaughton P.A. Specific involvement of PKC-e in sensitization of the neuronal response to painful heat. 1999 University of Cambridge   Cesare, P.
Dekker, L.V.
Sardini, A.
McNaughton P.A. A novel heat-activated current in nociceptive neurones and its sensitization by bradykinin. 1996 University of Cambridge   Cesare, P.
Sitsapesan RMA Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor. 2000 University of Bristol   Chan,WM
Welch,W
Hemming K The preparation of 4-substituted pyrilium salts and their use in dienal synthesis 1996 University of Hertfordshire   Charoenying P
McKerrecher D
Taylor RJK
Warner T D Regulation of Cyclo-oxygenase Gene Expression in Rat Smooth Muscle Cells by Catalase. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Chen G
Kamal M
Hannon R
Morris RGM A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimers disease 2000 University of Edinburgh Neural Plasticity Chen G
Chen KS
Knox J
Martin SJ A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease 2000 University of Edinburgh Neural Plasticity Chen G
Chen KS
Knox J
MITCHESON J. A structural basis for drug-induced long QT syndrome 2000 University of Leicester   Chen J.
Lin M.
Culberson C.
MITCHESON J. Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel 2000 University of Leicester   Chen J.
Lin M.
Sanguinetti M.C.
MITCHESON J. Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate 2000 University of Leicester   Chen J.
Sanguinetti M.C.
Rang H.P. Capsaicin and carbon dioxide act by distinct mechanisms on sensory nerve terminals in the cat cornea. 1997 University College London Neuropharmacology and neuroscience Chen, X.
Belmonte, C.
Carter T.D. Porcine aortic endothelial gap junctions: identification and permeation by caged InsP3. 1996 University College London Receptors, ion channels and transduction Chen, X.Y
Carlile, G.
Kalapothakis, E.
Gould D J Immunotherapy of auto-immune diseases by gene transfer [In Process Citation] 1999 Queen Mary, University of London Bone and Joint Research Unit Chernajovsky Y
Annenkov A
Dreja H
Gould D J Immuno- and genetic therapy in autoimmune diseases. 2000 Queen Mary, University of London Bone and Joint Research Unit Chernajovsky Y
Dreja H
Daly C
Annenkov A E Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zeta [In Process Citation] 2000 Queen Mary, University of London Bone and Joint Research Unit Chernajovsky Y
Michel A.D. Ionic effects on human recombinant P2X7 receptor function. 1999 University of Cambridge   Chessell, I.P.
Humphrey, P.P.A.
GRUBB B.D. Cyclooxygenase-1 is a marker for a sub-population of putative nociceptive neurones in rat dorsal root ganglia 2000 University of Leicester   Chopra B.
Giblett S.
Little J.G.
Croxtall J D Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A549 cells. 1997 Queen Mary, University of London Biochemical Pharmacology Choudhury Q
White JO
Flower RJ
Croxtall J D Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism [In Process Citation] 2000 Queen Mary, University of London Biochemical Pharmacology Choudhury Q
Flower RJ
Croxtall J D Inhibitory effect of peptides derived from the N-terminus of lipocortin 1 on arachidonic acid release and proliferation in the A549 cell line: identification of E-Q-E-Y-V as a crucial component. 1998 Queen Mary, University of London Biochemical Pharmacology Choudhury Q
Flower RJ
Anggard E Photoplethysmographic assessment of pulse wave reflection: blunted response to endothelium-dependent beta2-adrenergic vasodilation in type II diabetes mellitus. 1999 Queen Mary, University of London Experimental Therapeutics Chowienczyk PJ
Kelly RP
MacCallum H
Jane DE Native NMDA receptors containing NR2A and NR2B subunits have pharmacologically-distinct competitive antagonist binding sites. 2000 University of Bristol   Christie,JM
Monaghan,DT
PATEL S Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhances the sensitivity of NAADP receptors for their ligand 2000 University of Oxford Integrative Biology Churchill, G.C.
Galione, A.
Irvine R.F. Nuclear targeting of the B isoform of Type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its a-helix 7. 2000 University of Cambridge   Ciruela, A.
Hinchcliffe, K. A.
Divecha, N
Hinchliffe K.A. PIPkins, their substrates and their products; new functions for old enzymes. 1998 University of Cambridge   Ciruela, A.
Irvine, R.F.
Hinchliffe K.A. Regulation of type IIa phosphatidylinositol phosphate kinase localisation by the protein kinase CK2. 1999 University of Cambridge   Ciruela, A.
Letcher, A.
Divecha, N.
Ford W.R. Opposite effects of angiotensin AT1 and AT2 receptor antagonists on recovery of mechanical function after ischemia-reperfusion in isolated working rat hearts. 1996 University of Cambridge   Clanachan, A.S.
Jugdutt, B.I.
Ford W.R. Intrinsic ANG II type 1 receptor stimulation contributes to recovery of postischemic mechanical function. 1998 University of Cambridge   Clanachan, A.S.
Lopaschuk, G.D.
Schulz, R.
SMITH AD Folate, vitamin B12 and serum total homocysteine levels in confirmed Alzheimer's disease 1998 University of Oxford Neuroscience Clarke, R.
Jobst, K.A.
Refsum, H.
Grootveld M Examination of the metabolic status of rat air pouch inflammatory exudate by high field proton NMR spectroscopy. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Claxson A
Chander C
Earl J
Plane F Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery 1997 University of Bristol   Cohen,RA
Najibi,S
Garland,CJ
Gilroy D W Inducible cyclooxygenase may have anti-inflammatory properties [see comments] 1999 Queen Mary, University of London Biochemical Pharmacology Colville-Nash PR
Willis D
Chivers J
Willis D. Inhibition of indicible nitric oxide synthase by peroxisome proliferator-activated receptor agonist: Correlation with induction of heme oxygenase 1. 1998 University College London Receptors, ion channels and transduction Colville-Nash, P.R.
Qureshi, S.S.
Willoughby, D.A.
Johnston A Effects of recombinent human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Comacho-Hubner C
Woods KA
Miraki-Moud F
COLEMAN MP The major brain isoform of Kif1b lacks the putative mitochondria-binding domain 1999 University of Oxford Neuroscience Conforti, L.
Buckmaster, E.A.
Tarlton, A.
Moss S.J. Subcellular localisation of gamma-aminobutyric acid type A receptors is determined by receptor beta subunits. 1996 University College London Receptors, ion channels and transduction Connolly, C. N.
Wooltorton, J. A.
Smart, T. G.
MacCallum P K Sex differences in the determinants of fibrinolytic activity. 1998 Queen Mary, University of London Experimental Therapeutics Cooper JA
Howarth DJ
Meade TW
Millar N.S. Upregulation of cell-surface alpha4beta2 neuronal nicotinic receptors by lower temperature and expression of chimeric subunits. 1999 University College London Receptors, ion channels and transduction Cooper, S . T.
Harkness, P. C.
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Millar N.S. Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor alpha 7 subunit. 1997 University College London Receptors, ion channels and transduction Cooper, S. T.
Forte P Basal nitric oxide synthesis in essential hypertension [see comments] 1997 Queen Mary, University of London Clinical Pharmacology Copland M
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Lobo M D Differential regulation of extracellular signal-regulated protein kinases (ERKs) 1 and 2 by cAMP and dissociation of ERK inhibition from anti-mitogenic effects in rabbit vascular smooth muscle cells. 1999 Queen Mary, University of London Clinical Pharmacology Cospedal R
Zachary I
Ribchester RR Competition at silent synapses in reinnervated skeletal muscle 2000 University of Edinburgh Neural Plasticity Costanzo EM
Barry JA
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Ribchester RR Co-regulation of synaptic efficacy at stable polyneuronally innervated neuromuscular junctions in reinnervated rat muscle 1999 University of Edinburgh Neural Plasticity Costanzo EM
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Moss S.J. Intracellular retention of recombinant GABAB receptors. 1998 University College London Receptors, ion channels and transduction Couve, A.
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GREENFIELD SA Heterogeneity of electrically evoked dopamine release and reuptake in substantia nigra, ventral tegmental area and striatum 1997 University of Oxford Neuroscience Cragg, S.J.
Rice, M.E.
GREENFIELD SA Differential autoreceptor control of somatodendritic and axon terminal dopamine release in substantia nigra, ventral tegmental area, and striatum 1997 University of Oxford Neuroscience Cragg, S.J.
Winstanley PA Effect of phenobarbital on seizure frequency and mortality in childhhood cerebral malaria 2000 University of Liverpool Tropical Pharmacology Crawley J
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Callingham B.A. Inhibitory effects of glibenclamide on the contraction of human arterial conduits used in coronary artery bypass surgery 2000 University of Cambridge   Crosbie, A.E.
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Chernajovsky Y Gene therapy for chronic relapsing experimental allergic encephalomyelitis using cells expressing a novel soluble p75 dimeric TNF receptor. 2000 Queen Mary, University of London Bone and Joint Research Unit Croxford JL
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Perretti M Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. 1996 Queen Mary, University of London Biochemical Pharmacology Croxtall JD
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Goulding NJ
Kidd B L Characterisation of capsaicin-induced mechanical hyperalgesia as a marker for altered nociceptive processing in patients with rheumatoid arthritis. 1997 Queen Mary, University of London Bone and Joint Research Unit Cruwys SC
Morris VH
Venkateswarlu K Signalling via ARF6 lies downstream of PI 3-kinase. 2000 University of Bristol   Cullen,PJ
Flower R J Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. 1997 Queen Mary, University of London Biochemical Pharmacology Cuzzocrea S
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Chatterjee P K Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress. 1999 Queen Mary, University of London Experimental Medicine and Nephrology Cuzzocrea S
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Chatterjee P K Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. 2000 Queen Mary, University of London Experimental Medicine and Nephrology Cuzzocrea S
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Mclean P G Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment [In Process Citation] 2000 Queen Mary, University of London Clinical Pharmacology D'Amico M
Di Filippo C
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Irvine R.F. Nuclei contain two differentially regulated pools of diacylglycerol. 1999 University of Cambridge   D'Santos, C.
Clarke, J.H.
Divecha, N.
Ramage A.G. The central action of the 5-HT2 receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cardiac inotropy and vascular resistance in the anaesthetized cat. 1998 University College London Neuropharmacology and neuroscience Daly, M. de B.
Waring M.J. Reactivity of guanine at m5CpG steps in DNA: evidence for electronic effects transmitted through the base pairs. 1999 University of Cambridge   Das, A.
Tang, K.S.
Gopalakrishnan, S.
Ismail FMD An exploration of the structure-activity relationships of 4-aminoquinolones: Novel antimalarials with activity in vivo 1996 University of Hertfordshire   Dascombe MJ
Carr P
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Ismail FMD Novel aryl-bis-quinolones with antimalarial activity in vivo 1998 University of Hertfordshire   Dascombe MJ
Carr PJ
Merette SAM
Winyard P G Simultaneous analysis of nitrite, nitrate and the nicotinamide nucleotides by capillary electrophoresis: application to biochemical studies and human extracellular fluids. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Davies CA
Perrett D
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Dunn SMJ Mutagenesis of the rat a1 subunit of the ?-aminobutyric acid receptor reveals the importance of residue 101 in determining the allosteric effects of benzodiazepine site ligands. 1999 University of Bristol   Davies,M
Muntoni,AL
Lambert,JJ
Kitteringham NR Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene 1996 University of Liverpool Drug Safety Davis C
Howard N
Pirmohamed M
NAHORSKI S.R. Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors 1999 University of Leicester   Davis R.J.
Challiss R.A.J.
Khoo SH Adenoviruses from human immunodeficiency virus-infected individuals, including two strains that represent new candidate serotypes Ad50 and Ad51 of subspecies B1 and D respectively 1999 University of Liverpool Pharmacology of HIV Disease De Jong JC
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Carrier M J Reactive oxygen species regulate macrophage scavenger receptor type I, but not type II, in the human monocytic cell line THP-1. 1998 Queen Mary, University of London Experimental Therapeutics De Kimpe SJ
Anggard EE
Coleman JW Reciprocal effects of interleukin-4 and interferon-g on immuno-globulin E-mediated mast cell degranulation: a role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate 1999 University of Liverpool Drug Safety DeSchoolmeester ML
Eastmond NC
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BLANK J.L. MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases 1999 University of Leicester   Deacon, K.
BLANK J.L. Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase1 and MKK3/p38 pathways regulated by MEK Kinase 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo 1997 University of Leicester   Deacon, K.
Brown D.A. Calcium channel gating and modulation by neurotransmitters depend on cellular compartmentalization. 2000 University College London Neuropharmacology and neuroscience Delmas, P.
Abogadie, F.C.
Buckley, N.J.
D'Cruz D Lymphocyte activation markers and von Willebrand factor antigen in Wegener's granulomatosis: potential markers for disease activity. 1999 Queen Mary, University of London Bone and Joint Research Unit Direskeneli H
Khamashta M
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BRUNSKILL N.J. Lysophosphatidic acid-induced calcium mobilization and proliferation in kidney proximal tubular cells 1999 University of Leicester   Dixon R.J.
Young K.W.
BRUNSKILL N.J. Lysophosphatidic acid-induced proliferation in opossum kidney proximal tubular cells: Role of PI 3-kinase and ERK 1999 University of Leicester   Dixon R.J.
BRUNSKILL N.J. Activation of mitogenic pathways by albumin in kidney proximal tubule epithelial cells: Implications for the pathophysiology of proteinuric states 1999 University of Leicester   Dixon R.J.
Richardson P.J. Expression profiling of single cells using three prime end amplification (TPEA) PCR. 1998 University of Cambridge   Dixon, A.
Lee, K.
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Richardson P.J. Correlating cell physiology with gene expression in single neurons 2000 University of Cambridge   Dixon, A.
Lee, K.
Bell, M.I.
Fitzgerald E.M. Maintenance of the K+ activity gradient in insect muscle compared in Diptera and Lepidoptera: Contributions of metabolic and exchanger mechanisms. 1996 University College London Neuropharmacology and neuroscience Djamgoz, M. B. A.
Dunbar, S. J.
Jane DE Antagonist activity of a-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells. 1999 University of Bristol   Doherty,AJ
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Fitzgerald E.M. Regulation of rat neuronal voltage-dependent calcium channels by endogenous p21-ras. 1997 University College London Neuropharmacology and neuroscience Dolphin, A. C.
Donaldson IML Afferent signals from the extraocular muscles affect the gain of the horizontal vestibulo-ocular reflex in the alert pigeon 2000 University of Edinburgh Neural Plasticity Donaldson IML
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Donaldson IML The functions of the proprioceptors of the eye muscles 2000 University of Edinburgh Neural Plasticity Donaldson IML
FORSYTHE I.D. Contrasting Ca2+ channel subtypes at cell bodies and synaptic terminals of rat anterioventral cochlear bushy neurones 1998 University of Leicester   Doughty, J.M.
Barnes-Davies M.,
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Plane F Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. 1999 University of Bristol   Doughty,JM
Langton,PD
McQueen DS P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint 1998 University of Edinburgh Neuropharmacology Dowd E
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Chessell IP
Foreman J.C. Cutaneous responses to endothelin-1 and histamine in patients with vibration white finger. 1998 University College London Receptors, ion channels and transduction Dowd, P. M.
Goldsmith, P. C.
Chopra, S.
BRADING AF Structural and functional denervation of human detrusor after spinal cord injury 2000 University of Oxford Integrative Biology Drake, M.J.
Hedlund, F.
Mills, I.W.
Annenkov A E Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritis. 2000 Queen Mary, University of London Bone and Joint Research Unit Dreja H
Chernajovsky Y
Wood ER Neurotoxic hippocampal lesions have no effect on odor span and little effect on odor recognition memory but produce significant impairments on spatial span, recognition, and alternation 2000 University of Edinburgh Neural Plasticity Dudchenko PA
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Eichenbaum H
Jenkinson D.H. Discrimination between subtypes of apamin-sensitive Ca 1996 University College London Receptors, ion channels and transduction Dunn, P. M.
Benton, D. C. H.
Campos Rosa, J.
Usowicz MM Differential inhibition of Ca2+ channels in mature rat cerebellar Purkinje cells by sFTX-3.3 and FTX-3.3 1996 University of Bristol   Dupere,JRB
Moya,E
Blagbrough,IS
Benjamin N Helicobacter pylori is killed by nitrite under acidic conditions. 1998 Queen Mary, University of London Clinical Pharmacology Dykhuizen A
Fraser A
McKenzie
Benjamin N Antimicrobial effect of acidified nitrite on gut pathogens: importance of dietary nitrate in host defense. 1996 Queen Mary, University of London Clinical Pharmacology Dykhuizen PS
Frazer R
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Forte P Nitric oxide synthesis in patients with infective gastroenteritis. 1999 Queen Mary, University of London Clinical Pharmacology Dykhuizen RS
Milne E
McKenzie
Benjamin N Plasma nitrate concentration in infective gastroenteritis and inflammatory bowel disease. 1996 Queen Mary, University of London Clinical Pharmacology Dykhuizen RS
Masson J
McKnight G
Coleman JW Nitric oxide inhibits IgE-mediated degranulation of mast cellsand is the principal intermediate in IFN-g-induced suppression of exocytosis 1997 University of Liverpool Drug Safety Eastmond NC
Banks EMS
GRUBB B.D. The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an upregulation of cyclooxygenase-2 in the spinal cord 1999 University of Leicester   Ebersberger A.
Willingale H.L.
Gardiner N.J.
Yaqoob M T Modulation of hypoxia-induced calpain activity in rat proximal tubules. 1996 Queen Mary, University of London Experimental Medicine and Nephrology Edelstein CL
Alkhunaizi AM
Gengaro PE
Poole AW Thrombin-induced association of SHP-2 with multiple tyrosine-phosphorylated proteins in human platelets. 1999 University of Bristol   Edmead,CE
Crosby,D
Southcott,MJG
Gibb A.J. Properties of ATP receptor-mediated synaptic transmission in the rat medial habenula. 1997 University College London Neuropharmacology and neuroscience Edwards, F. A.
Robertson, S. J.
Koenig J.A. Somatostatin receptors in Neuro2A neuroblastoma cells: operational characteristics. 1997 University of Cambridge   Edwardson, J.M.
Humphrey, P.P.A.
Koenig J.A. Somatostatin receptors in Neuro2A neuroblastoma cells: ligand internalization. 1997 University of Cambridge   Edwardson, J.M.
Humphrey, P.P.A.
Haycox AR Cost-effectiveness of treatment for GORD in clinical practice 1998 University of Liverpool Prescribing Research Group Eggleston A
Wigerinck A
Huijghebgert S
Wood ER The hippocampus, memory, and place cells: Is it spatial memory or a memory space? 1999 University of Edinburgh Neural Plasticity Eichenbaum H
Dudchenko PA
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Henderson R.M. Direct observation of DNA translocation and cleavage by the EcoKI endonuclease using atomic force microscopy. 1999 University of Cambridge   Ellis, D.J.
Dryden, D.T.
Berge, T.
Berge T. Investigation of protein partnerships using atomic force microscopy. 1999 University of Cambridge   Ellis, D.J.
Edwardson, J.M.
Henderson, R.M.
Berge T. Translocation-independent dimerization of the EcoK1 endonuclease visualized by atomic force microscopy. 2000 University of Cambridge   Ellis, D.J.
Dryden, D.T.
Edwardson, J.M.
Genazzani A.A. Unique inactivation properties of NAADP-sensitive Ca2+ release 1996 University of Cambridge   Empson, R.M.
Galione, A.
EVANS R.J. The role of positively charged amino acids in ATP recognition by human P2X1 receptors 2000 University of Leicester   Ennion S.
Hagan S.
NAGY Z Cell cycle markers in the hippocampus in Alzhemier's disease 1997 University of Oxford Neuroscience Esiri, M.M.
Cato, A.M.
Smith, A.D.
NAGY Z The effects of additional pathology on the cognitive deficit in Alzheimer's disease 1997 University of Oxford Neuroscience Esiri, M.M.
Jobst, K.A.
Morris, J.H.
NAGY Z Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease 1999 University of Oxford Neuroscience Esiri, M.M.
Smith, M.Z.
Barnetson, L.
Goulding N J Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. 1998 Queen Mary, University of London Biochemical Pharmacology Euzger HS
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GRUBB B.D. Characterization of cultured dorsal root ganglion neuron P2X receptors 1999 University of Leicester   Evans R.J
Donaldson IML Signals of eye position and velocity in the first-order afferents from pigeon extraocular muscles 1998 University of Edinburgh Neural Plasticity Fahy FL
Donaldson IML
Poole AW Glycoprotein GP Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor g-chain, Fyn and Lyn, to activate human platelets. 1999 University of Bristol   Falati,S
Edmead,CE
Moss G.W.J. Structure-activity relationships for the interaction of bovine pancreatic trypsin inhibitor with an intracellular site on a large conductance Ca 2000 University College London Receptors, ion channels and transduction Favre, I.
Goldenberg, D.P.
Otlewski, J.
Sellers L.A. Activated G protein-coupled receptor induces tyrosine phosphorylation of STAT3 and agonist-selective serine phosphorylation via sustained stimulation of mitogen-activated protein kinase. 1999 University of Cambridge   Feniuk, W.
Humphrey, P.P.A.
Lauder, H.
Callingham B.A. Monoamine oxidase activities in human cystic and colonic arteries - influence of age. 1998 University of Cambridge   Figueiredo, I.V.
Martinez Coscolla, A.
Cotrim, M.D.
Barnard E.A. The P2Y1 receptor closes the N-type Ca2+ channel in neurones, with both adenosine trisphosphates and diphosphates as potent agonists. 2000 University of Cambridge   Filippov, A.K.
Brown, D.A.
Sharkey J Recommendations for standards regarding preclinical neuroprotective and restorative drug development 1999 University of Edinburgh Neuropharmacology Finklestein SP
Fisher M
Furlan AJ
Finlayson K Detection of adenosine receptor antagonists in rat brain using a modified radioreceptor assay 1997 University of Edinburgh Neuropharmacology Finlayson K
Butcher SP
Sharkey J
PAULSEN OKH Cholinergic induction of network oscillations at 40Hz in the hippocampus in vitro 1998 University of Oxford Neuroscience Fisahn, A.
Pike, F.G.
Buhl, E.H.
Getting S J Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. 1997 Queen Mary, University of London Biochemical Pharmacology Flower RJ
Parente L
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Getting S J Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. 1997 Queen Mary, University of London Biochemical Pharmacology Flower RJ
Perretti M
Thorn P. Microtubules regulate local Ca2+ spiking in secretory epithelial cells. 2000 University of Cambridge   Fogarty, K. E.
Kidd, J. F.
Turner, A.
Thorn P. A bimodal pattern of InsP3-evoked elementary Ca2+ signals in pancreatic acinar cells. 2000 University of Cambridge   Fogarty, K.E.
Kidd, J.F.
Tuft, R.A.
O'Byrne S Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion. 2000 Queen Mary, University of London Clinical Pharmacology Forte P
Roberts LJ
Morrow JD
Kelly PAT Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats 1997 University of Edinburgh Neuropharmacology Fouyas IP
Kelly PAT
Ritchie IM
Kelly PAT Cerebrovascular responsiveness to NG-nitro-L-arginine methyl ester in spontaneously diabetic rats 1996 University of Edinburgh Neuropharmacology Fouyas IP
Kelly PAT
Ritchie IM
Gould D J Potentiation of TNF-alpha toxicity by conjugation with ricin A-chain. 1998 Queen Mary, University of London Bone and Joint Research Unit Foxwell BM
Feldmann M
Chernajovsky Y
Thiemermann C Identification of copper/zinc superoxide dismutase as a novel nitric oxide-regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats. 1999 Queen Mary, University of London Experimental Medicine and Nephrology Frank S
Zacharowski K
Wray GM
Marrion NV A novel lipid-anchored A-kinase anchoring protein facilitates cAMP-responsive membrane events 1998 University of Bristol   Fraser,IDC
Tavalin,SJ
Lester,LB
Winyard P G Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite. 1996 Queen Mary, University of London Pharmaceutical Bioanalysis Frears ER
Zhang Z
Blake DR
Pitcher J.A. Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies. 1996 University College London Receptors, ion channels and transduction Fredericks, Z. L.
Stone, W. C.
Premont, R. T.
Pitcher J.A. G protein-coupled receptor kinases. 1998 University College London Receptors, ion channels and transduction Freedman, N. J.
Lefkowitz, R. J.
Kidd B L A multicenter, randomized, double blind study comparing lornoxicam with diclofenac in osteoarthritis. 1996 Queen Mary, University of London Bone and Joint Research Unit Frenzel W
Morris RGM Synaptic tagging and long term potentiation 1997 University of Edinburgh Neural Plasticity Frey U
Morris RGM
McNaughton P.A. Actions of serum and plasma albumin on [Ca2+]i in human endothelial cells. 1997 University of Cambridge   Fuentes, E.
Nadal, A.
Jacob, R.
CAPOGNA M Organotypic slice cultures: a technique has come of age 1996 University of Oxford Neuroscience Gahwiler, B.H.
Debanne, D.
McKinney, R.A.
CAPOGNA M Calcium-independent actions of alpha-latrotoxin on spontaneous and evoked synaptic transmission in the hippocampus 1996 University of Oxford Neuroscience Gahwiler, B.H.
Thompson, S.M.
Genazzani A.A. Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive pool 1996 University of Cambridge   Galione, A
CHURCHILL GC Spatial control of calcium signaling by NAADP diffusion and gradients 2000 University of Oxford Integrative Biology Galione, A.
Young J.M. Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]-g-aminobutyric acid release from depolarisation-stimulated slices of rat substantia nigra pars reticulata. 1997 University of Cambridge   Garcia, M.
Floran, B.
Arias-Montano, J.A.
Kidd B L Effect of streptozotocin-diabetes on knee joint inflammation-induced changes in substance P and nerve growth factor in the rat. 1996 Queen Mary, University of London Bone and Joint Research Unit Garrett NE
Cruwys SC
Tomlinson DR
BLANK J.L. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase 1996 University of Leicester   Gerwins, P.
Elliott, E.M.
Sather, S.
WATSON SP Collagen receptor signalling in platelets: extending the role of the ITAM 1998 University of Oxford Integrative Biology Gibbins, J.
Poole AW The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen 1997 University of Bristol   Gibbins,JM
Turner,M
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Getting S J POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. 1999 Queen Mary, University of London Biochemical Pharmacology Gibbs L
Clark AJ
Flower RJ
Walley TJ Lifestyle Medicines 2000 University of Liverpool Prescribing Research Group Gilbert D
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Pirmohamed M The effect of the CYP2C9 genetic polymorphisms on sulphamethoxazole N-hydroxylation 1999 University of Liverpool Drug Safety Gill HJ
Kitteringham NR
Park BK
Kitteringham NR The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat 1997 University of Liverpool Drug Safety Gill HJ
Hough SJ
Naisbitt DJ
Willis D. Evidence that inducible cyclooxygenase may have anti-inflammatory properties. 1999 University College London Receptors, ion channels and transduction Gilroy, D.
Colville-Nash, P.
Paul-Clark, M.
Warner T D Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis [published erratum appears in Proc Natl Acad Sci U S A 1999 Aug 17;96(17):9666] 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Giuliano F
Vojnovic I
Bukasa A
NICOTERA PL The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown 1997 University of Leicester   Gohring, F.
Schwab, B.L.
Leist, M.
Foreman J.C. Inhibitors of nitric oxide synthase in human skin. 1996 University College London Receptors, ion channels and transduction Goldsmith, P. C.
Leslie, T. A.
Hayes, N. A.
de Hoz L Contingent versus incidental context processing during conditioning: dissociation after excitotoxic hippocampal plus dentate gyrus lesions 1998 University of Edinburgh Neural Plasticity Good M
de Hoz L
Morris RGM
Anggard E Evaluation of the postprandial effects of a fast-food meal on human plasma F(2)-isoprostane levels. 2000 Queen Mary, University of London Experimental Therapeutics Gopaul NK
Zacharowski K
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Chan W L A proinflammatory role for IL-18 in rheumatoid arthritis [see comments] 1999 Queen Mary, University of London Bone and Joint Research Unit Gracie JA
Forsey RJ
Gilmour A
SANTORO B Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels 1997 University of Oxford Neuroscience Grant, S.G.N.
Bartsch, D.
Kandel, E.R.
Usowicz MM Ca2+ entry following store depletion in SH-SY5Y neuroblastoma cells 1996 University of Bristol   Grudt,TJ
Henderson,G
Henderson G Glycine and GABAA receptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by 1998 University of Bristol   Grudt,TJ
Venkateswarlu K EGF-and NGF-stimulated translocation of cytohesin-1 to the plasma membrane of PC12 cells requires PI 3-kinase activation and a functional cytohesin-1 PH domain. 1999 University of Bristol   Gunn-Moore,FJ
Tavar
Cullen,PJ
Hladky S.B. Hypotonicity-induced anion fluxes in cells expressing the multidrug resistance associated protein, MRP. 1996 University of Cambridge   Hainsworth, A.H.
Henderson, R.M.
Hickman, M.E.
Khoo SH Influenza-like episodes in HIV-positive patients: the role of viral and atypical infections 1998 University of Liverpool Pharmacology of HIV Disease Hajia M
Klapper PE
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Brown D.A. The alpha subunit of Gq contributes to muscarinic inhibition of the M-type potassium current in sympathetic neurons. 1998 University College London Neuropharmacology and neuroscience Haley, J.E.
Abogadie, F.C.
Delmas, P.
Pitcher J.A. The G protein-coupled receptor kinase is a microtubule-associated protein kinase that phosphorylates tubulin. 1998 University College London Receptors, ion channels and transduction Hall, R. A.
Daaka, Y.
Zhang, J.
Gibb A.J. Fast purinergic synaptic transmission in the central nervous system. 1996 University College London Neuropharmacology and neuroscience Halliday, F. C.
Warner T D Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: consequences for nonsteroidal antiinflammatory drug efficacy. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Hamilton LC
Mitchell JA
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MITCHESON J. An investigation of the role played by the E-4031-sensitive (rapid delayed rectifier) potassium current in isolated rabbit atrioventricular nodal and ventricular myocytes 1999 University of Leicester   Hancox J.C.
Moss S.J. The protein MAP-IB links GABAC receptors to the cytoskeleton at retinal synapses. 1999 University College London Receptors, ion channels and transduction Hanley, J. G.
Koulen, P.
Bedford, F. K.
Perrett D Novel three-dimensional capillary electrophoresis system for complex and trace analyis. 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Hanna M
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Edwardson J.M. Identification of SNAREs involved in regulated exocytosis in the pancreatic acinar cell. 1999 University of Cambridge   Hansen, N.J.,
Antonin, W.
NICOTERA PL Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity 1999 University of Leicester   Hansson, O
Petersen, A
Leist, M
Harmar AJ Nomenclature of Receptors for Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide 1998 University of Edinburgh Neuropharmacology Harmar AJ
Arimura A
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Nissim A Screening of phage antibody libraries. 1996 Queen Mary, University of London Bone and Joint Research Unit Harrison JL
Williams SC
Winter G
Kozlowski RZ Functional evidence for a novel suramin-insensitive pyrimidine receptor in rat small pulmonary arteries. 1998 University of Bristol   Hartley,SA
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Kozlowski RZ Electrophysiological consequences of purinergicreceptor stimulation in isolated rat pulmonary arterial myocytes. 1997 University of Bristol   Hartley,SA
Colquhoun D. Properties of single ion channel currents elicited by a pulse of agonist concentration or voltage. 1997 University College London Receptors, ion channels and transduction Hawkes, A.G.
Merlushkin, A.
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Donaldson IML Changes in dorsal neck muscle activity related to imposed eye movement in the decerebrate pigeon 1997 University of Edinburgh Neural Plasticity Hayman MR
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WILLARS G.B. Lack of a C-terminal tail in the mammalian gonadotropin -releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization 1999 University of Leicester   Heding A.
Vrecl M.
Sellar R.
Berge T. Preconditioning of c-plane sapphire for GaN molecular beam epitaxy by electron cyclotron resonance plasma nitridation 1998 University of Cambridge   Heinlein, C.
Grepstad, J.K.
Einfeldt, S.
Berge T. Patterned regrowth of n-GaAs by molecular beam epitaxy using arsenic passivation 1999 University of Cambridge   Heinlen, C.
Fimland, B-O.
Grepstad, J.K.
Stocker M. Subunit assembly and domain analysis of electrically silent K+ channel alpha-subunits of the rat Kv9 subfamily. 1999 University College London Receptors, ion channels and transduction Hellwig, M.
Kerschensteiner, D.
Park BK Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi 2000 University of Liverpool Drug Safety Henderson CJ
Wolf CR
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Sharkey J A rat model of Endothelin-3-induced middle cerebral artery occlusion with controlled reperfusion 1999 University of Edinburgh Neuropharmacology Henshall DC
Butcher SP
Sharkey J
Chernajovsky Y Mutation of proline 211 reduces shedding of the human p75 TNF receptor. 1998 Queen Mary, University of London Bone and Joint Research Unit Herman C
CHALLISS R.A.J. Complex involvement of pertussis toxin-sensitive G-proteins in the regulation of type 1alpha metabotropic glutamate receptor signalling in BHK cells 2000 University of Leicester   Hermans E.
Saunders R.
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Grootveld M Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: the roles of endogenous pyruvate and lactate. Relevance to inflammatory joint diseases. 1997 Queen Mary, University of London Pharmaceutical Bioanalysis Herz H
Blake DR
Goyal M Pulmonary tuberculosis in Harare, Zimbabwe: analysis by spoligotyping 1998 University of Hertfordshire   Heyderman RS
Roberts P
Ushewokunze S
Michel A.D. Apparent species differences in the kinetic properties of P2X7 receptors. 2000 University of Cambridge   Hibell, A.D.
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Morton A.J. Mice transgenic for the Huntington's Disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity 2000 University of Cambridge   Hickey, M.A.
White R The actions of the cannabinoid receptor antagonist, SR141716A, in the rat isolated mesenteric artery. 1998 University of Cambridge   Hiley, C.R.
White R Effects of K+ channel openers on relaxations to nitric oxide and endothelium-derived hyperpolarizing factor in rat mesenteric artery. 1998 University of Cambridge   Hiley, C.R.
Ismail FMD An inhibitor of the sodium pump obtained from human placenta 1996 University of Hertfordshire   Hilton PJ
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Irvine R.F. Aggregation-dependent, integrin-mediated increases in cytoskeletally associated PtdInsP2(4,5) levels in human platelets are controlled by translocation of PtdIns 4-P 5-kinase C to the cytoskeleton. 1996 University of Cambridge   Hinchliffe, K.A.,
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Young J.M. Ca2+/calmodulin-mediated regulation of agonist-induced sequestration of Gq protein-coupled histamine H1-receptors in human U373 MG astrocytoma cells. 1998 University of Cambridge   Hishinuma, S.
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Bishop-Bailey D Bisphenol A diglycidyl ether (BADGE) is a PPARgamma agonist in an ECV304 cell line. 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Hla T
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Bishop-Bailey D Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Hla T
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Murrell-Lagnado R.D. Molecular determinants for sodium-dependent activation of G protein-gated K+ channels. 1999 University of Cambridge   Ho, I.H.M.
Johnston A Therapeutic drug monitoring of immunosuppressant drugs. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Holt DW
Johnston A New approaches to Cyclosporine monitoring raise further concerns about analytical techniques. 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Holt DW
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Fan T.P.D. Differential effects of angiostatic steroids and dexamethasone on angiogenesis and cytokine levels in rat sponge implants. 1996 University of Cambridge   Hori, Y.
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Kitteringham NR Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity 1999 University of Liverpool Drug Safety Hough SJ
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MacIntyre I Developmental regulation of nitric oxide synthase expression in rat skeletal bone. 1999 Queen Mary, University of London Clinical Pharmacology Hukkanen MVJ
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Grant SGN Proteomic analysis of NMDA receptor-adhesion protein signaling complexes 2000 University of Edinburgh Neural Plasticity Husi H
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Arbuthnott GW Plasticity of striatopallidal terminals following unilateral lesion of the dopaminergic nigrostriatal pathway: A morphological study 1997 University of Edinburgh Neural Plasticity Ingham CA
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Hinchliffe K.A. Regulation of PtdIns 4-P 5-kinase C by thrombin-stimulated changes in its phosphorylation state in human platelets. 1998 University of Cambridge   Irvine, R.F.
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Ismail FMD Mechanism of formation of benzene-2-thiol 1998 University of Hertfordshire   Isaccs NS
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Olverman HJ Pyrazolopyridine derivatives act as competitive antagonists of brain adenosine A1 receptors: [35S]GTPgS binding studies 1999 University of Edinburgh Neuropharmacology Ito H
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Willoughby D A The codependence of angiogenesis and chronic inflammation. 1997 Queen Mary, University of London Biochemical Pharmacology Jackson JR
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Kabouridis P The role of lipid rafts in T cell antigen receptor (TCR) signalling. 2000 Queen Mary, University of London Bone and Joint Research Unit Janes PW
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Kabouridis P Cholesterol depletion disrupts membrane rafts and modulates the activity of multiple signalling pathways in T cells. 2000 Queen Mary, University of London Bone and Joint Research Unit Janzen J
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Feniuk W. Selective somatostatin sst2 receptor blockade with the novel cyclic octapeptide, CYN-154806. 2000 University of Cambridge   Jarvie, E.
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Jacobs M. Modulation of vascular tone by low density lipoproteins: effects on L-arginine transport and nitric oxide synthesis. 1997 University College London Receptors, ion channels and transduction Jay, M.T.
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GABBOTT PLA Calretinin neurons in human medial prefrontal cortex (areas 24a,b,c, 32' and 25) 1996 University of Oxford Neuroscience Jays, P.R.
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SMITH AD Use of structural imaging to study the progression of Alzheimer's disease 1996 University of Oxford Neuroscience Jobst, K.A.
POMPEO F Autophosphorylation of phosphoglucosamine mutase from Escherichia coli 2000 University of Oxford Pharmacogenetics + Toxicology Jolly, L.
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Sharkey J New use of a macrolide compound 2000 University of Edinburgh Neuropharmacology Jones P
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Sihra T.S. Synapsins as mediators of BDNF-enhanced neurotransmitter release. 2000 University College London Neuropharmacology and neuroscience Jovanovic, J. N.
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Ford W.R. Influence of b-adrenoceptor tone on the cardioprotective efficacy of adenosine A1 receptor acativation in isolated working rat hearts. 2000 University of Cambridge   Jugdutt, B.I.
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Skehel PA Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons 2000 University of Edinburgh Neural Plasticity Kaether C
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Ahluwalia A Cholinergic Contraction is Altered in nNOS Knockouts: Co-operative Modulation of Neural Bronchoconstriction by nNOS and COX 1999 Queen Mary, University of London Clinical Pharmacology Kakuyama M
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STANDEN N.B. Mechanisms that regulate [Ca2+]i following depolarisation in rat systemic arterial smooth muscle cells 2000 University of Leicester   Kamishima, T.
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Gergely F.V. The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. 2000 University of Cambridge   Karlsson, C.
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EVANS AM Relaxation of endothelin-1-induced pulmonary arterial constriction by niflumic acid and NPPB: Mechanism(s) independent of chloride channel block 1999 University of Oxford Integrative Biology Kato, K.
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Kozlowski RZ Relaxation of endothelin-1 induced pulmonary arterial constriction by niflumic acid and NPPB: mechanism(s) independent of chloride channel block. 1999 University of Bristol   Kato,K
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Koenig J.A. Fates of endocytosed somatostatin sst2 receptors and associated agonists. 1998 University of Cambridge   Kaur, R.
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Kelly JS Alzheimer's disease: the tacrine legacy 1999 University of Edinburgh Neuropharmacology Kelly JS
Perrett D Determination of taurine in plasma by capillary zone electrophoresis following derivatisation with fluorescamine [In Process Citation] 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Kelly MT
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Kelly PAT 7-Nitroindazole reduces cerebral blood flow following chronic nitric oxide synthase inhibition 2000 University of Edinburgh Neuropharmacology Kelly PAT
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Kelly PAT Intracerebral fetal raphe implants normalize hippocampal function but not cerebrovascular control in serotonin-depleted adult rat brain 1998 University of Edinburgh Neuropharmacology Kelly PAT
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Thiemermann C Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ failure. 1998 Queen Mary, University of London Experimental Medicine and Nephrology Kengatharan KM
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Ferguson D.R. ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - a possible sensory mechanism? 1997 University of Cambridge   Kennedy, I.
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MacCallum P K Clinical characteristics determining the mode of presentation in patients with acute coronary syndromes. 1998 Queen Mary, University of London Experimental Therapeutics Kennon S
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Stocker M. Heteromeric assembly of Kv9.3 with Kv2.1: Effect on the state-dependence of inactivation 1999 University College London Receptors, ion channels and transduction Kerschensteiner, D.
Henderson G ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain 1998 University of Bristol   Khakh,BS
Henderson G ATP-gated cation channels (P2x purinoceptors) in trigeminal mesencephalic nucleus neurones of the rat 1997 University of Bristol   Khakh,BS
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Jacobs M. 3-Nitrotyrosine in the proteins of human plasma determined by an ELISA method. 1998 University College London Receptors, ion channels and transduction Khan, J.
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Gergely F.V. D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo. 2000 University of Cambridge   Kidd, D.
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Thorn P. The role of Ca2+ feedback in shaping InsP3-evoked Ca2+ signals in mouse pancreatic acinar cells. 1999 University of Cambridge   Kidd, J.F.
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Park BK Hepatocellular response to chemical stress in CD-1 mice: Induction of early genes and g-glutamylcysteine synthetase 2000 University of Liverpool Drug Safety Kitteringham NR
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Forte P Evidence for a difference in nitric oxide biosynthesis between healthy women and men. 1998 Queen Mary, University of London Clinical Pharmacology Kneale BJ
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Ramage A.G. Evidence for a role for central 5-HT2B as well as 5-HT2A receptors in cardiovascular regulation in anaesthetized rats. 1999 University College London Neuropharmacology and neuroscience Knowles, I. D.
Caulfield M J Essential hypertension in African Caribbeans associates with a variant of the beta2-adrenoceptor. 1997 Queen Mary, University of London Clinical Pharmacology Kotanko P
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STANDEN N.B. Angiotensin II inhibition of ATP-sensitive K+ currents in rat arterial smooth muscle cells through protein kinase C 1997 University of Leicester   Kubo, M.
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Skehel PA Dendritic localization of mRNAs 1998 University of Edinburgh Neural Plasticity Kuhl D
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Schoepfer R. Mutiple structural elements determine subunit-specificity of Mg2+ block in NMDA receptor channels. 1996 University College London Receptors, ion channels and transduction Kuner, T.
Sandin JSBE Dose- and time-dependent bimodal effects of k-opioid agonists on locomotor activity in mice 2000 University of Edinburgh Neural Plasticity Kuzmin A
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Anggard E Investigation of endogenous nitric oxide vascular function in the carotid artery of cholesterol-fed rabbits. 1996 Queen Mary, University of London Experimental Therapeutics Laight D
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Carrier M J Endothelial dysfunction accompanies a pro-oxidant, pro-diabetic challenge in the insulin resistant, obese Zucker rat in vivo. 2000 Queen Mary, University of London Experimental Therapeutics Laight DW
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Carrier M J Investigation of oxidant stress and vasodepression to glyceryl trinitrate in the obese Zucker rat in vivo. 1998 Queen Mary, University of London Experimental Therapeutics Laight DW
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Carrier M J Pro-oxidant challenge in vivo provokes the onset of NIDDM in the insulin resistant obese Zucker rat. 1999 Queen Mary, University of London Experimental Therapeutics Laight DW
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Venkateswarlu K The N-terminal membrane domain of yeast NADPH-cytochrome P450 Oxidoreductase is not required for catalytic activity in sterol biosynthesis or in reconstitution of CYP activity. 1998 University of Bristol   Lamb,DC
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Corder R Endothelin-2 synthesis is stimulated by the type-1 tumour necrosis factor receptor and cAMP: comparison with endothelin-converting enzyme-1 expression. 2000 Queen Mary, University of London Experimental Therapeutics Lambert GL
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Larkman PM Characterization of 5-HT-sensitive potassium conductances in neonatal rat facial motoneurones in vitro 1998 University of Edinburgh Neuropharmacology Larkman PM
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Larkman PM Modulation of IH by 5-HT in neonatal rat motoneurones In Vitro: Mediation through a phosphorylation independent action of cAMP 1997 University of Edinburgh Neuropharmacology Larkman PM
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Whittle B J Endogenous nitric oxide in the maintenance of rat microvascular integrity against widespread plasma leakage following abdominal laparotomy. 1999 Queen Mary, University of London Experimental Therapeutics Laszlo F
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Fan T.P.D. Quantification of the repair process involved in the repair of a cell monolayer using an in vitro model of mechanical injury. 1998 University of Cambridge   Lauder, H.
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Caulfield M J Angiotensinogen in human essential hypertension. 1996 Queen Mary, University of London Clinical Pharmacology Lavender P
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Goyal M Spoligotyping in Molecular epidemiology of Tuberculosis in Ghana 1999 University of Hertfordshire   Lawn SD
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Johnston A Measurement of sirolimus in whole blood using high-performance liquid chromatography with ultraviolet detection. 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Lee T
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SMITH AD Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease 1997 University of Oxford Neuroscience Lehmann, D.J.
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NICOTERA PL 1-methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation and neuronal apoptosis 1998 University of Leicester   Leist, M.
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Millar N.S. The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. 1997 University College London Receptors, ion channels and transduction Lewis, T. M.
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DART C. The dependence of Ag+-block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter 1998 University of Leicester   Leyland, M.L.
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DART C. The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis 1998 University of Leicester   Leyland, M.L.
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La M Comparison of the effects of hydroxocobalamin and oxyhaemoglobin on responses to NO, EDRF and the nitrergic transmitter. 1996 Queen Mary, University of London Biochemical Pharmacology Li CG
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Perretti M Promoting detachment of neurophils adherent to murine post-capillary venules to control inflammation: Effect of lipocortin 1. 1998 Queen Mary, University of London Biochemical Pharmacology Lim LHK
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DAVIES N.W. A residue in the intracellular vestibule of the pore is critical for gating and permeation in Ca2+-activated K+ (BKca) channels 2000 University of Leicester   Lippiat, J.D.
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DAVIES N.W. Block of cloned BKCa channels (rSlo) expressed in HEK 293 cells by N-methyl D-glucamine 1998 University of Leicester   Lippiat, J.D.
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ROEPER J The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels 1999 University of Oxford Neuroscience Liss, B.
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ROEPER J Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic in midbrain neurons 1999 University of Oxford Neuroscience Liss, B.
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SANTORO B Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain 1998 University of Oxford Neuroscience Liu, D.T.
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Ford W.R. K(ATP)-channel activation: Effects on myocardial recovery from ischaemia and role in the cardioprotective response to adenosine A1-receptor stimulation. 1998 University of Cambridge   Lopaschuk, G.D.
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Shen S Structure of the human VIPR2 gene for vasoactive intestinal peptide receptor type 2 1999 University of Edinburgh Neuropharmacology Lutz EM
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CHALLISS R.A.J. Stable overexpression of the type-1 inositol 1,4,5-trisphosphate receptor in L fibroblasts: subcellular distribution and functional consequences 1996 University of Leicester   Mackrill J.J.
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Kabouridis P S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. 1997 Queen Mary, University of London Bone and Joint Research Unit Magee AI
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Edwards IG The biliary metabolites of b-artemether, an endoperoxide antimalarial 1997 University of Liverpool Tropical Pharmacology Maggs JL
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BOLAM PB Relationship of activity in the subthalamic nucleus-globus pallidus network to cortical electroencephalogram 2000 University of Oxford Neuroscience Magill, P.J.
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Morris RGM The functional neuroanatomy of comprehension and memory: the importance of prior knowledge 1999 University of Edinburgh Neural Plasticity Maguire EA
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MacIntyre I Modulation of the effects of Osteoprotegerin (OPG) Ligand in Human Leukemic Cell Line by OPG and Calcitonin. 2000 Queen Mary, University of London Clinical Pharmacology Mancini L
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MacIntyre I Nitric oxide superoxide and peroxynitrite modulate osteoclast activity. 1998 Queen Mary, University of London Clinical Pharmacology Mancini L
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MacIntyre I The biphasic effects of nitric oxide in primary rat osteoblasts are cGMP dependent. 2000 Queen Mary, University of London Clinical Pharmacology Mancini L
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Walley TJ The General Practice Research Database 1999 University of Liverpool Prescribing Research Group Mantgani A
Taylor C.W. Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity. 1997 University of Cambridge   Marchant, J.S.
van Veen H.W. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. 2000 University of Cambridge   Margolles, A.
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Winyard P G Activation of the transcription factor nuclear factor-kappaB in human inflamed synovial tissue. 1996 Queen Mary, University of London Pharmaceutical Bioanalysis Marok R
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Moss G.W.J. An evolutionarily conserved binding site for serine proteinase inhibitors in large conductance calcium-activated potassium channels. 1996 University College London Receptors, ion channels and transduction Marshall, J.
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Olverman HJ Pharmacological characterisation of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques 1998 University of Edinburgh Neuropharmacology Marston HM
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Marston H Pharmacological characterization of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques 1998 University of Edinburgh Neuropharmacology Marston HM
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Marston H Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat 1999 University of Edinburgh Neuropharmacology Marston HM
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Kelly JS New use of aminopiperazine derivatives 1998 University of Edinburgh Neuropharmacology Marston HM
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Finlayson K Pharmacological characterization of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques 1998 University of Edinburgh Neuropharmacology Marston HM
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Martin SJ Synaptic plasticity and memory: an evaluation of the hypothesis 2000 University of Edinburgh Neural Plasticity Martin SJ
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SIM E Mapping AAC1, AAC2 and AACP, the genes for arylamine N-acetyltranferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours 1997 University of Oxford Pharmacogenetics + Toxicology Matas, N.
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EMPTAGE NJ Threshold serotonin concentration required to produce synaptic facilitation differs for depressed and nondepressed synapses in Aplysia sensory neurons 1996 University of Oxford Neuroscience Mauelshagen, J.
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WILLARS G.B. Acute desensitization of phospholipase C-coupled muscarinic M3 receptors but not gonadotropin-releasing hormone receptors co-expressed in alphaT3-1 cells: implications for mechanisms of rapid desensitization 1998 University of Leicester   McArdle, C.A.
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Olverman HJ Effects of the specific serotonin reuptake inhibitor, citalopram upon local cerebral blood flow and glucose utilisation in the rat 1999 University of Edinburgh Neuropharmacology McBean DE
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DAVIES N.W. A rate theory model for Mg2+ block of ATP-dependent potassium channels of rat skeletal muscle 1996 University of Leicester   McKillen, H.-C.
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CAPOGNA M Miniature synaptic events maintain dendritic spines via AMPA receptor activation 1999 University of Oxford Neuroscience McKinney, R A
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CAPOGNA M Ca2+ or Sr2+ partially rescues synaptic transmission in hippocampal cultures treated with botulinium toxin A and C, but not tetanus toxin 1997 University of Oxford Neuroscience McKinney, R.A.
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Perretti M Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules. 2000 Queen Mary, University of London Biochemical Pharmacology McLean PG
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McQueen DS Secretoneurin: a novel carotid body peptide 1996 University of Edinburgh Neuropharmacology McQueen DS
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McQueen DS Activation of P2X receptors for adenosine triphosphate evokes cardiorespiratory reflexes in anaesthetized rats 1998 University of Edinburgh Neuropharmacology McQueen DS
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Born G V R Effect of captopril and losartan on blood pressure and accumulation of LDL and fibrinogen by aortic wall and other tissues in normotensive and hypertensive rats. 1997 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Medina R
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Dolphin A.C. Known calcium channel alpha1 subunits can form low threshold small conductance channels with similarities to native T-type channels. 1998 University College London Neuropharmacology and neuroscience Meir, A.
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Thomas P. The LbT2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion. 1996 University of Cambridge   Mellon, P.L.
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Breckenridge AM Pharmacokinetics of combination therapy with nelfinavir plus nevirapine. 1998 University of Liverpool Pharmacology of HIV Disease Merry C
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Breckenridge AM Saquinavir kinetics alone and in combination with ritonavir in HIV infected patients 1997 University of Liverpool Pharmacology of HIV Disease Merry C
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Back DJ Interaction of sildenafil and indinavir when co-administered to HIV-positive patients 1999 University of Liverpool Pharmacology of HIV Disease Merry C
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Matthews E.K. A key role for the mitochondrial benzodiazepine receptor in cellular photosensitisation with d-aminolaevulinic acid. 2000 University of Cambridge   Mesenholler, M.
Genazzani A.A. Kinetic properties of Nicotinic Acid Adenine Dinucleotide Phosphate--induced Ca2+release. 1997 University of Cambridge   Mezna, M.
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Ferguson D.R. Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells. 2000 University of Cambridge   Michea, L.
Peters, E.M.
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Gergely F.V. The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila. 1997 University of Cambridge   Micklem, D.R.
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Grant SGN Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein 1998 University of Edinburgh Neural Plasticity Migaud M
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Michel A.D. Cibacron blue allosterically modulates the rat P2X4 receptor. 1998 University of Cambridge   Miller, K.J.
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Michel A.D. Radiolabeling of the rat P2X4 purinoceptor: evidence for allosteric interactions of purinoceptor antagonists and monovalent cations with P2X purinoceptors. 1997 University of Cambridge   Miller, K.J.
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Callingham B.A. Changes in reactivity of the digital artery of the fallow deer, Dama dama, in summer and winter. 1999 University of Cambridge   Milton, A.S.
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Wyllie DJA Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells 2000 University of Edinburgh Neuropharmacology Misra C
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Cull-Candy S.G. Identification of subunits contributing to synaptic and extrasynaptic NMDA receptors in Golgi cells of the rat cerebellum. 2000 University College London Neuropharmacology and neuroscience Misra, C.
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Munroe P B Spectrum of mutations in the Batten disease gene, CLN3. 1997 Queen Mary, University of London Clinical Pharmacology Mitchison HM
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Hemming K A clean and efficient synthesis of 5-(2'-fluoro-2',3'-dimethylbutanyl-3'-yl) substituted 1,2,4-oxadiazoles using silver tetrafluoroborate as a fluorodesulfurization reagent 2000 University of Hertfordshire   Morgan DT
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Morris RGM Impaired spatial learning after saturation of long-term potentiation 1998 University of Edinburgh Neural Plasticity Moser EI
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Anggard E F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease. 1999 Queen Mary, University of London Experimental Therapeutics Nourooz-Zadeh
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Winstanley PA Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum 2000 University of Liverpool Tropical Pharmacology Nzila AM
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Park BK Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether 1999 University of Liverpool Drug Safety O'Neill PM
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Harmar AJ Polymorphism in serotonin transporter gene associated with susceptibility to major depression 1996 University of Edinburgh Neuropharmacology Ogilvie AD
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Khoo SH Tumour Necrosis Factor c2 microsatellite allele is associated with the rate of HIV disease progression 1997 University of Liverpool Pharmacology of HIV Disease Ollier WER
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SHARP T Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate in the brain 2000 University of Oxford Neuroscience Patel, S.
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SEWARD E.P. P2Y purinoceptors inhibit exocytosis in adrenal chromaffin cells via modulation of voltage-operated calcium channels 2000 University of Leicester   Powell A.D.
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Kitteringham NR Expression of cytochrome P4502E1 in human liver: assessment by mRNA, genotype and phenotype 1998 University of Liverpool Drug Safety Powell H
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Skehel PA A tri-hybrid system for the analysis and detection of RNA-protein interactions 1996 University of Edinburgh Neural Plasticity Putz U
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Chernajovsky Y Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis. 1999 Queen Mary, University of London Bone and Joint Research Unit Rabinovitch G
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SIM E Structure of arylamine N-acetyltransferase reveals a catalytic triad 2000 University of Oxford Pharmacogenetics + Toxicology Sinclair, J.C.
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Thomas P. Tetrabutylammonium: a selective blocker of the somatostatin-activated hyperpolarizing current in mouse AtT-20 corticotrophs. 2000 University of Cambridge   Smith, P.
MCILHINNEY RAJ Molecular characterization of two structurally distinct groups of human Homers, generated by extensive alternative splicing 2000 University of Oxford Neuroscience Soloviev, M.M.
Ciruela, F.
Chan, W.Y.
Barnard E.A. Xenopus oocytes express a unitary glutamate receptor endogenously. 1997 University of Cambridge   Soloviev, M.M.
Dickenson A.H. Warm coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. 2000 University College London Neuropharmacology and neuroscience Souslova, V.
Cesare, P.
Ding, Y.
Kozlowski RZ A novel anionic conductance affects action potential duration in isolated rat ventricular myocytes. 2000 University of Bristol   Spencer,CI
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PAULSEN OKH Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo 1998 University of Oxford Neuroscience Sprenge, R.
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Amico, C.
Grant SGN Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo 1998 University of Edinburgh Neural Plasticity Sprengel R
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Hladky S.B. Adjustments for the display of quantized ion channel dwell times in histograms with logarithmic bins. 2000 University of Cambridge   Stark, J.A.
EMPTAGE NJ Pharmacological and kinetic characterization of two functional classes of serotonergic modulation in Aplysia sensory neurons 1996 University of Oxford Neuroscience Stark, L.L.
Mercer, A.R.
Carew, T.J.
Hoffman R Wound fluid from venous leg ulcers degrades plasminogen and reduces plasmin generation by keratinocytes 1998 University of Hertfordshire   Starkey S
Coad J
Garthwaite J. Vicious cycle involving Na+ channels, glutamate release and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation. 1996 University College London Neuropharmacology and neuroscience Strijbos, P. J. L. M.
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Walley TJ Interpretation of data protection legislation - barriers to research 2000 University of Liverpool Prescribing Research Group Strobl J
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BRUNSKILL N.J. Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase 1998 University of Leicester   Stuart J.
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Cull-Candy S.G. Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition. 1997 University College London Neuropharmacology and neuroscience Swanson, G. T.
Kamboj, S. K.
Flower R J Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. 1997 Queen Mary, University of London Biochemical Pharmacology Szabo C
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Koenig J.A. Involvement of receptor cycling and receptor reserve in resensitization of muscarinic responses in SH-SY5Y human neuroblastoma cells. 1998 University of Cambridge   Szekeres, P.G.
Edwardson, J.M.
Edwardson J.M. The relationship between agonist intrinsic activity and the rate of endocytosis of muscarinic receptors in a human neuroblastoma cell line. 1998 University of Cambridge   Szekeres, P.G.
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Flower R J Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC. 1999 Queen Mary, University of London Biochemical Pharmacology Tailor A
Tomlinson A
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FORSYTHE I.D. Presynaptic calcium current modulation by a metabotropic glutamate receptor 1996 University of Leicester   Takahashi, T.
Tsujimoto T.
Barnes-Davies M
SOMOGYI P Proximally targeted GABAergic synapses and gap junctions synchronize cortical interneurons 2000 University of Oxford Neuroscience Tamas, G.
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Foreman J.C. The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells. 1999 University College London Receptors, ion channels and transduction Tatla, S.
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Marrion NV Selective activation of calcium-activated potassium channels by colocalized calcium channels in hippocampal neurons 1998 University of Bristol   Tavalin,SJ
Goyal M Genotypic analysis of Mycobacterium tuberculosis from medieval human remains 1999 University of Hertfordshire   Taylor GM
Legge AJ
Shaw RJ
Perrett D Analysis of coricosteroids in biofluids by capillary electrochromatography with gradient elution. 1997 Queen Mary, University of London Pharmaceutical Bioanalysis Taylor MR
Teale P
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Matthews E.K. Dynamics of actin measured by fluorescence correlation microscopy (FCM). 1996 University of Cambridge   Terry, B.R.
Seward EP Bidirectional modulation of exocytosis by angiotensin II involves multiple G-protein-regulated transduction pathways in chromaffin cells. 2000 University of Bristol   Teschemacher,AG
Pitcher J.A. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. 1999 University College London Receptors, ion channels and transduction Tesmer, J. J.
Freeman, J. L.
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Vane J Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat. 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Thiemermann C
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Jane DE Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. 1998 University of Bristol   Thomas,NK
Hawkins,LM
Miller,JC
Mills P G Extent of oxidative modification of low density lipoprotein determines the degree of cytotoxicity to human coronary artery cells. 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Thorne SA
Abbot SE
Winyard PG
Mills P G Modified low density lipoprotein and cytokines mediate monocyte adhesion to smooth muscle cells. 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Thorne SA
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Yaqoob M T Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy. 2000 Queen Mary, University of London Experimental Medicine and Nephrology Thuraisingham RC
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SANTORO B The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels 1999 University of Oxford Neuroscience Tibbs, G.R.
NAHORSKI S.R. Identification of a novel receptor kinase that phosphorylates a phospholipase C-linked muscarinic receptor 1996 University of Leicester   Tobin A.B.
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Gilroy D W Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. 1998 Queen Mary, University of London Biochemical Pharmacology Tomlinson A
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Gilroy D W Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation [see comments] 1998 Queen Mary, University of London Biochemical Pharmacology Tomlinson A
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Roberts PJ Inhibition of AMPA receptor-stimulated 57Co2+ influx by D- and L-2-amino-4-phosphonobutanoic acid (L-AP4) and L-serine-O-phosphate (L-SOP) in cultured cerebellar granule cells 1997 University of Bristol   Toms,NJ
Hawkins,LM
Roberts PJ The effects of (RS)-a-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist 1996 University of Bristol   Toms,NJ
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TOBIN A.B. Stimulus-Dependent Phosphorylation of G-Protein Coupled Receptors By Casein Kinase 1alpha 1997 University of Leicester   Totty N.F.
Sterlin A.E.
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SEWARD E.P. Bidirectional modulation of exocytosis by angiotensin II involves multiple G-protein-regulated transduction pathways in chromaffin cells 2000 University of Leicester   Treschemacher A.G.
Chernajovsky Y Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy. 1999 Queen Mary, University of London Bone and Joint Research Unit Triantaphyllopoulos KA
Williams RO
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Hladky S.B. Streaming potentials in gramicidin channels measured with ion selective microelectrodes. 1998 University of Cambridge   Tripathi, S.
FORSYTHE I.D. Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse 1998 University of Leicester   Tsujimoto T.
Barnes-Davies M.
Cuttle M.F.
Benjamin N Effect of nitric-oxide-generating system on microcirculatory blood flow in skin of patients with severe Raynaud's syndrome: a randomised trial. 1999 Queen Mary, University of London Clinical Pharmacology Tucker AT
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Foreman J.C. Involvement of kinins in the hyperresponsiveness induced by platelet activating factor in the human nasal airway. 2000 University College London   Turner, P. J.
Dear, J. W.
BRADING AF Smooth muscle of the bladder in the normal and the diseased state: pathophysiology, diagnosis and treatment 1997 University of Oxford Integrative Biology Turner, W.H.
Nissim A Human single-chain Fv fragments specific for natural killer cell receptors from phage display libraries. 2000 Queen Mary, University of London Bone and Joint Research Unit Uchanska-Ziegler B
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Volz A
Haycox AR The North Staffordshire Community beds study 1999 University of Liverpool Prescribing Research Group Unsworth L
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Wall MJ Development of the quantal properties of evoked and spontaneous synaptic currents at a brain synapse 1998 University of Bristol   Usowicz,MM
Wall MJ Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum 1997 University of Bristol   Usowicz,MM
Nissim A Specific inhibition of the reaction between a tumor-inhibitory antibody and Erb-2 receptor by a mimotype derived from a phage display library. 2000 Queen Mary, University of London Bone and Joint Research Unit Vaisman N
Klapper LN
Tirosh B
McNaughton P.A. Modulation of the synaptic Ca2+ current in salamander photoreceptors by polyunsaturated fatty acids and retinoids. 2000 University of Cambridge   Vellani, V.
Reynolds, M.R.
van Veen H.W. Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1. 1996 University of Cambridge   Venema, K.
Bolhuis, B.
Oussenko, I.
Edwards IG Synthesis and antimalarial activity of sixteen dispiro-1,2,4,5-tetroxane analogs of WR 148999 1998 University of Liverpool Tropical Pharmacology Vennerstrom J
Dong Y
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Naisbitt DJ Plasma cysteine deficiency and decreased reduction of nitrosulfamethoxazole with HIV infection 2000 University of Liverpool Drug Safety Vilar FJ
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NICOTERA PL ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation 1999 University of Leicester   Volbracht, C.
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Usowicz MM Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum 1997 University of Bristol   Wall,MJ
Usowicz MM Development of the quantal properties of evoked and spontaneous synaptic currents at a brain synapse 1998 University of Bristol   Wall,MJ
Haycox AR An integrated national pharmaceutical policy for the United Kingdom? 1998 University of Liverpool Prescribing Research Group Walley T
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Fan T.P.D. Sequential development of angiotensin receptors and angiotensin converting enzyme during angiogenesis in the rat subcutaneous sponge granuloma. 1997 University of Cambridge   Walsh, D.A.
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Wharton, J.
Moss S.J. GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton. 1999 University College London Receptors, ion channels and transduction Wang, H. W.
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Ramage A.G. Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats. 2000 University College London Neuropharmacology and neuroscience Wang, Y.
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CAVIERES J.D. Binding of 2'(3')-O-(2,4,6- trinitrophenyl)ADP to soluble alphabeta protomers of Na,K-ATPase modified with fluorescein isothiocyanate - Evidence for two distinct nucleotide sites 1996 University of Leicester   Ward D.G.
CAVIERES J.D. Affinity labeling of two nucleotide sites on Na,K-ATPase using 2 1998 University of Leicester   Ward D.G.
Matthews E.K. Cytotoxic, nuclear, and growth inhibitory effects of photodynamic drugs on pancreatic carcinoma cells. 1996 University of Cambridge   Ward, A.J.
CAVIERES J.D. Photoinactivation of fluorescein isothiocyanate-modified Na,K-ATPase by 2'(3')-0-(2,4,6-trinitrophenyl)8-azidoadenosine 5'-diphosphate. Abolition of E1 and E2 partial reactions by sequential block of high and low-affinity nucleotide sites 1998 University of Leicester   Ward, D.G.
Thomas P. Modulation of stimulus-secretion coupling in single rat gonadotrophs. 1997 University of Cambridge   Waring, D.W.
Winstanley PA Chlorproguanil-dapsone: an effective treatment for uncomplicated falciparum malaria. 1997 University of Liverpool Tropical Pharmacology Watkins W
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Barnard E.A. Molecular cloning and characterisation of the rat P2Y4 receptor. 1998 University of Cambridge   Webb, T.E.
Henderson, D.J.
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Barnard E.A. The P2Y purinoceptor in rat brain microvascular endothelial cells couples to inhibition of adenylate cyclase. 1996 University of Cambridge   Webb, T.E.
Feolde, F.
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La M Human soluble guanylate cyclase: functional expression and revised isoenzyme family. 1998 Queen Mary, University of London Biochemical Pharmacology Weeger M
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Barrand M.A. Functional and molecular characterization of a volume-sensitive chloride current in rat brain endothelial cells. 1999 University of Cambridge   Weikersthal von, S.F.
Hladky, S.B.
STANDEN N.B. ATP-sensitive K+ channel activation by calcitonin gene-related peptide and protein kinase A in pig coronary arterial smooth muscle 1998 University of Leicester   Wellman, G.C.
Quayle, J.M.
Hladky S.B. Use of membrane vesicles to investigate drug interactions with transporter proteins, P-glycoprotein and multidrug resistance-associated protein. 2000 University of Cambridge   Wheeler, R.
Neo, S.-Y.
Chew, J.
Matthews E.K. Photosensitizon of pancreatic tumour cells by d -aminolaevulinic acid esters. 2000 University of Cambridge   Whitaker, C.J.
Battah, S.H.
Forsyth, M.J.
Hiley C.R. Hyperpolarisation of rat mesenteric endothelial cells by ATP-sensitive K+ channel openers. 2000 University of Cambridge   White, R.
Hiley C.R. The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. 1998 University of Cambridge   White, R.
Hiley C.R. A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. 1997 University of Cambridge   White, R.
Hiley C.R. Endothelium and cannabinoid receptor involvement in levcromakalim vasorelaxation. 1997 University of Cambridge   White, R.
Arbuthnott GW Dopamine reverses the depression of rat cortico-striatal synapses which normally follows high frequency stimulation of cortex in vitro 1996 University of Edinburgh Neural Plasticity Wickens JR
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Arbuthnott GW Effects of potassium channel blockers on synaptic plasticity in the corticostriatal pathway 1998 University of Edinburgh Neural Plasticity Wickens JR
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Sihra T.S. An essential role for a small synaptic vesicle-associated phosphatidylinositol 4-kinase in neurotransmitter release. 1998 University College London Neuropharmacology and neuroscience Wiedemann, C.
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Timmis A D Comparison of case fatality in south Asian and white patients after acute myocardial infarction: observational study [see comments] 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Wilkinson P
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Barakat K How should age affect management of acute myocardial infarction? A prospective cohort study [see comments] 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Wilkinson P
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Barakat K Acute myocardial infarction in women: contribution of treatment variables to adverse outcome [In Process Citation] 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Wilkinson P
Suliman A
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Feniuk W. Characterization of human recombinant somatostatin sst5 receptors mediating activation of phosphoinositide metabolism. 1997 University of Cambridge   Wilkinson, G.F.
Humphrey, P.P.A.
CHALLISS R.A.J. Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells 1998 University of Leicester   Willars, G.B
Nahorski, S.R.
Kelly EP Selective reduction in A2 adenosine receptor desensitization following antisense-induced suppression of G protein-coupled receptor kinase 2 expression. 1999 University of Bristol   Willets,JM
Parent,J-L
Benovic,JL
Coleman JW Tumour necrosis factor-a expression and cell recruitment in Sephadex particle-induced lung inflammation: effects of dexamethasone and cyclosporin A 1997 University of Liverpool Drug Safety Williams CMM
Smith L
Flanagan BF
Pirmohamed M Intracellular glutathione in the peripheral blood cells of HIV-infected patients: failure to show a deficiency 1996 University of Liverpool Drug Safety Williams DP
Wilkins EGL
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Naisbitt DJ Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs 1998 University of Liverpool Drug Safety Williams DP
Maggs JL
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Humphrey P.P.A. Somatostatin5 receptor-mediated [35S]Guanosine-5'-0-(3-thio)triphosphate binding: agonist potencies and the influence of sodium chloride on intrinsic activity. 1997 University of Cambridge   Williams, A .J.
Michel, A.D.
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GRUBB B.D. Prostanoids synthesised by cyclooxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability 1997 University of Leicester   Willingale, H.L.
Gardiner, N.J.
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Willoughby D A Heme oxygenase: a novel target for the modulation of the inflammatory response. 1996 Queen Mary, University of London Biochemical Pharmacology Willis D
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GALIONE A Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway 1996 University of Oxford Integrative Biology Willmott, N.J.
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Colville-Nash P R Cyclopentenone prostaglandins-new allies in the war on inflammation [news] 2000 Queen Mary, University of London Biochemical Pharmacology Willoughby DA
Moore AR
Walley TJ Influences of practice characteristics on prescribing in fundholding and non-fundholding general practices 1996 University of Liverpool Prescribing Research Group Wilson R
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EVANS AM ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor: a primary role for cADPR in hypoxic pulmonary vasoconstriction 2000 University of Oxford Integrative Biology Wilson, H. L.
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Marshall I. Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. 1998 University College London Receptors, ion channels and transduction Wisskirchen, F. M.
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Gibb A.J. Single channel properties of P2X ATP receptors in outside-out patches from rat hippocampal granule cells. 2000 University College London Neuropharmacology and neuroscience Wong, A. Y. C.
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Young J.M. Characateristics of the Ca2+-dependent inhibition of cyclic AMP accumulation by histamine and thapsigargin inhuman U373 MG astrocytoma cells. 2000 University of Cambridge   Wong, M.-P.W.
Cooper, D.M.F.
Young, K.W.
Wood ER The global record of memory in hippocampal neuronal activity 1999 University of Edinburgh Neural Plasticity Wood ER
Dudchenko PA
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Wood ER Hippocampal neurons encode information about different types of memory episodes occurring in the same location 2000 University of Edinburgh Neural Plasticity Wood ER
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Warner T D Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Woods M
Mitchell JA
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Murrell-Lagnado R.D. Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channels. 1997 University of Cambridge   Woodward, R.
Stevens, E.B.
Stanford S.C. Modulation of sibutramine-induced increases in extracellular noradrenaline concentration in rat frontal cortex and hypothalamus by alpha2-adrenoceptors. 1999 University College London Neuropharmacology and neuroscience Wortley, K.E.
Heal, D.J.
Arbuthnott GW Double anterograde tracing of outputs from adjacent barrel columns of rat somatosensory cortex. Neostriatal projection patterns and terminal ultrastructure 1999 University of Edinburgh Neural Plasticity Wright AK
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BLANK J.L. Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G protein-linked muscarine acetylcholine receptors 1999 University of Leicester   Wylie P.G.
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Wyllie DJA Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors 1998 University of Edinburgh Neuropharmacology Wyllie DJA
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Colquhoun D. Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. 1998 University College London Receptors, ion channels and transduction Wyllie, D.J.A.
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Chan W L Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium. 1998 Queen Mary, University of London Bone and Joint Research Unit Xu D
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Chan W L Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. 1998 Queen Mary, University of London Bone and Joint Research Unit Xu D
Leung BP
Hunter D
Chan W L Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. 1998 Queen Mary, University of London Bone and Joint Research Unit Xu D
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Huang F
NAHORSKI S.R. Lysophosphatidic acid-induced Ca2+ mobilisation requires intracellular sphingosine 1-phosphate production: potential involvement of endogenous Edg-4 receptors 2000 University of Leicester   Young K.W.
Bootman M.D.
Channing D.R.
Young J.M. Dual effects of histamine and substance P on intracellular calcium levels in human U373 MG astrocytoma cells: role of protein kinase C. 1998 University of Cambridge   Young, K.W.
Pinnock, R.D.
Gibson, W.J.
Chatterjee P K Lipoteichoic acid induces delayed protection in the rat heart: a comparison with endotoxin. 2000 Queen Mary, University of London Experimental Medicine and Nephrology Zacharowski K
Frank S
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Chatterjee P K Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo. 2000 Queen Mary, University of London Experimental Medicine and Nephrology Zacharowski K
Cuzzocrea S
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Lobo M D Nuclear localization and apoptotic regulation of an amino-terminal. 2000 Queen Mary, University of London Clinical Pharmacology Zachary I
Mills P G The role of signal averaged P wave duration and serum magnesium as a combined predictor of atrial fibrillation after elective coronary artery bypass surgery. 1997 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Zaman AG
Alamgir F
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Mills P G Atrial fibrillation after coronary artery bypass surgery: a model for preoperative risk stratification. 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Zaman AG
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Kabouridis P Inhibition of TCR/CD3-mediated signaling by a mutant of the hematopoietically expressed G16 GTP-binding protein. 1998 Queen Mary, University of London Bone and Joint Research Unit Zhou J
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Carter T.D. Membrane capacitance changes induced by thrombin and calcium in single endothelial cells cultured from human umbilical vein. 1998 University College London Receptors, ion channels and transduction Zupancic, G.
Smith, S.M.
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SMITH AD Abnormal function of potassium channels in platelets of patients with Alzheimer's disease 1998 University of Oxford Neuroscience de Silva, H.A.
Aronson, J.K.
Grahame-Smith, D.G.
POMPEO F Probing the role of cysteine residues in glucosamine-1-phosphate acetyltransferase activity of the bifunctional GlmU protein from Escherichia coli: site-directed mutagenesis and characterization of the mutant enzymes 1998 University of Oxford Pharmacogenetics + Toxicology van Heijenoort, J.
Mengin-Lecreulx, D.
Barrand M.A. Changes in anion permeability following hypotonic challenge in rat brain endothelial cells: a comparison of responses in primary cultures and in immortalised RBE-4 cells. 1997 University of Cambridge   von Weikersthal, S.F.
Seetharaman, S.
Wright, K.A.
Barrand M.A. Hypotonicity-induced changes in anion permeability of cultured rat brain endothelial cells. 1996 University of Cambridge   von Weikersthal, S.F.
Hickman, M.E.
Hladky, S.B.
Stanford S.C. Prozac: panacea or puzzle? 1996 University College London Neuropharmacology and neuroscience  
Sitsapesan RMA DIDS, DBDS and suramin cause similar modifications to cardiac ryanodine receptor function. 1999 University of Bristol    
Sellers L.A. Prolonged activation of extracellular signal-regulated kinase by a protein kinase C-dependent and N17Ras-insensitive mechanism mediates the proliferative response of Gi/o-coupled somatostatin sst4 receptors. 1999 University of Cambridge    
Marrion NV Control of M-current. 1997 University of Bristol    
Marrion NV Calcineurin regulates M-channel modal gating in sympathetic neurons. 1996 University of Bristol    
Gibb A.J. Receptors linked to ion channels: activation and block. 1996 University College London Neuropharmacology and neuroscience  
Fitzgerald E.M. Regulation of voltage-dependent calcium channels in rat sensory neurones involves a Ras/mitogen-activated protein kinase pathway. 2000 University College London Neuropharmacology and neuroscience  
Ferguson D.R. Urothelial function. 1999 University of Cambridge    
Corder R The conformation of human big endothelin-1 favours endopeptidase hydrolysis of the TRP21-VAL22 bond. 1996 Queen Mary, University of London Experimental Therapeutics  
Colquhoun D. Binding, gating, affinity and efficacy. The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. 1998 University College London Receptors, ion channels and transduction  
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