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| Pharmacology - Publications | ||||
| Pharmacology RDF, 895kb <RDF Zip, 75kb> | |||
| People, 91kb | Publications, 389kb | Groups, 9kb | Institutions, 28kb |
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| Author | Title | Date | Place of Publication | Research Group | Co-Authors |
| van Veen H.W. | The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. | 2000 | University of Cambridge | Margolles, A. Muller, M. Higgins, C.F. |
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| Young J.M. | Characateristics of the Ca2+-dependent inhibition of cyclic AMP accumulation by histamine and thapsigargin inhuman U373 MG astrocytoma cells. | 2000 | University of Cambridge | Wong, M.-P.W. Cooper, D.M.F. Young, K.W. |
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| Yaqoob M T | Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy. | 2000 | Queen Mary, University of London | Experimental Medicine and Nephrology | Thuraisingham RC Nott CA Dodd SM |
| Wyllie DJA | Single-channel analysis of a NMDA receptor possessing a mutation in the region of the glutamate binding site | 2000 | University of Edinburgh | Neuropharmacology | Anson LC Schoepfer R Colquhoun D |
| Wyllie DJA | Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells | 2000 | University of Edinburgh | Neuropharmacology | Misra C Brickley SG Wyllie DJA |
| Wood ER | Neurotoxic hippocampal lesions have no effect on odor span and little effect on odor recognition memory but produce significant impairments on spatial span, recognition, and alternation | 2000 | University of Edinburgh | Neural Plasticity | Dudchenko PA Wood ER Eichenbaum H |
| Wood ER | Hippocampal neurons encode information about different types of memory episodes occurring in the same location | 2000 | University of Edinburgh | Neural Plasticity | Wood ER Dudchenko PA Robitsek RJ |
| Winstanley PA | Effect of phenobarbital on seizure frequency and mortality in childhhood cerebral malaria | 2000 | University of Liverpool | Tropical Pharmacology | Crawley J Waruiru C Mithwani S |
| Winstanley PA | Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum | 2000 | University of Liverpool | Tropical Pharmacology | Nzila AM Nduati E Watkins WM |
| Winstanley PA | Towards an understanding of the mechanism of pyrimethamine- sulfadoxine resistance in Plasmodium falciparum: the genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. | 2000 | University of Liverpool | Tropical Pharmacology | N'zila A Sibley C Mberu E |
| Willoughby D A | COX-1, COX-2, and COX-3 and the future treatment of chronic inflammatory disease. | 2000 | Queen Mary, University of London | Biochemical Pharmacology | Moore AR Colville-Nash PR |
| Willis D. | Heme oxygenase isoform expression in immediate and delayed type hypersensitivity reactions in the rat pleural cavity. | 2000 | University College London | Receptors, ion channels and transduction | Moore, A.R. Willoughby, D.A. |
| Whittle B J | Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobactor pylori: inhibition by superoxide dismutase. | 2000 | Queen Mary, University of London | Experimental Therapeutics | Moran AP Szepes Z Delchier JC |
| White R | Human urotensin-II is an endothelium-dependent vasodilator in rat small arteries. | 2000 | University of Cambridge | Bottrill, F.E. Douglas, S.A. Hiley, C.R. |
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| White R | Interaction of cyclic AMP modulating agents with levcromakalim in the relaxation of rat isolated mesenteric artery. | 2000 | University of Cambridge | Omar, R. Bottrill, F.E. Hiley, C.R. |
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| Waring M.J. | Quinaxaline antibiotics enhance peptide nucleic acid binding to double-stranded DNA. | 2000 | University of Cambridge | Mollegaard, N.E. Bailly, C. Nielsen, P.E. |
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| Walley TJ | Interpretation of data protection legislation - barriers to research | 2000 | University of Liverpool | Prescribing Research Group | Strobl J Pickworth E |
| Walley TJ | Lifestyle Medicines | 2000 | University of Liverpool | Prescribing Research Group | Gilbert D New B |
| WATSON SP | Phosphatidylinositol 3,4,5-trisphosphate regulates Ca2+ entry via Btk in platelets and megakaryocytes without increasing phospholipase C activity | 2000 | University of Oxford | Integrative Biology | Pasquet, J-M. Quek, L. Stevens, C. |
| WATSON SP | Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation | 2000 | University of Oxford | Integrative Biology | Berlanga, O. Bobe, R. Becker, M. |
| Venkateswarlu K | Signalling via ARF6 lies downstream of PI 3-kinase. | 2000 | University of Bristol | Cullen,PJ | |
| Timmis A D | Magnitude and consequences of error in coronary angiography interpretation (the ACRE study) [In Process Citation] | 2000 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Banerjee S Crook AM Dawson JR |
| Thorn P. | A bimodal pattern of InsP3-evoked elementary Ca2+ signals in pancreatic acinar cells. | 2000 | University of Cambridge | Fogarty, K.E. Kidd, J.F. Tuft, R.A. |
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| Thorn P. | Microtubules regulate local Ca2+ spiking in secretory epithelial cells. | 2000 | University of Cambridge | Fogarty, K. E. Kidd, J. F. Turner, A. |
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| Thomas P. | Real-time studies of zymogen granule exocytosis in intact rat pancreatic acinar cells. | 2000 | University of Cambridge | Campos-Toimil, M. Edwardson, J.M. |
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| Thomas P. | Tetrabutylammonium: a selective blocker of the somatostatin-activated hyperpolarizing current in mouse AtT-20 corticotrophs. | 2000 | University of Cambridge | Smith, P. | |
| Taylor C.W. | Parathyroid hormone controls the size of the intracellular Ca2+ stores available to receptors linked to inositol trisphosphate formation. | 2000 | University of Cambridge | Short, A.D. | |
| TOBIN A.B. | Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha | 2000 | University of Leicester | Budd D.C. McDonald J.E. |
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| Stocker M. | Differential distribution of three Ca2+-activated K+ channel subunits SK1, SK2, and SK3 in the adult rat central nervous system. | 2000 | University College London | Receptors, ion channels and transduction | Pedarzani, P. |
| Stanford S.C. | Differences in cenral noradrenergic and behavioural responses of Maudsley non-reactive and Maudsley reactive inbred rats on exposure to an aversive novel environment. | 2000 | University College London | Neuropharmacology and neuroscience | McQuade, R. |
| Stanford S.C. | A microdialysis study of the noradrenergic response in rat frontal cortex and hypothalamus to a conditioned cue for aversive, naturalistic environmental stimuli. | 2000 | University College London | Neuropharmacology and neuroscience | McQuade, R. |
| Skehel PA | Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons | 2000 | University of Edinburgh | Neural Plasticity | Kaether C Skehel P Dotti CG |
| Skehel PA | Mouse VAP33 is associated with the endoplasmic reticulum and microtubules | 2000 | University of Edinburgh | Neural Plasticity | Skehel PA Fabian-Fine R Kandel ER |
| Sitsapesan RMA | Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor. | 2000 | University of Bristol | Chan,WM Welch,W |
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| Sihra T.S. | A modulatory role for protein phosphatase 2B (calcineurin) in the regulation of Ca | 2000 | University College London | Neuropharmacology and neuroscience | Burley, J. R. |
| Sihra T.S. | Synapsins as mediators of BDNF-enhanced neurotransmitter release. | 2000 | University College London | Neuropharmacology and neuroscience | Jovanovic, J. N. Czernik, A. J. Fienberg, A. A. |
| Shen S | Overexpression of the human VPAC2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice | 2000 | University of Edinburgh | Neuropharmacology | Shen S Spratt C Sheward WJ |
| Shen S | Refined mapping of the human serotonin transporter (SLC6A4) gene within 17q11 adjacent to the CPD and NF1 genes | 2000 | University of Edinburgh | Neuropharmacology | Shen S Battersby S Weaver M |
| Sharkey J | New use of a macrolide compound | 2000 | University of Edinburgh | Neuropharmacology | Jones P Sharkey J Kelly JS |
| Seward EP | Bidirectional modulation of exocytosis by angiotensin II involves multiple G-protein-regulated transduction pathways in chromaffin cells. | 2000 | University of Bristol | Teschemacher,AG | |
| Seward EP | P2Y purinoceptors inhibit exocytosis in adrenal chromaffin cells via modulation of voltage-operated calcium channels. | 2000 | University of Bristol | Powell,AD Teschemacher,AG |
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| Sellers L.A. | Receptor isoforms mediate opposing proliferative effects through Gbg-activated p38 or Akt pathways. | 2000 | University of Cambridge | Alderton, F. Carruthers, A.M. Schindler, M. |
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| Schoepfer R. | Single-channel analysis of a NMDA receptor possessing a mutation in the region of the glutamate binding site. | 2000 | University College London | Receptors, ion channels and transduction | Anson, L. C. Colquhoun, D. Wyllie, D. J. A |
| Sandin JSBE | Dose- and time-dependent bimodal effects of k-opioid agonists on locomotor activity in mice | 2000 | University of Edinburgh | Neural Plasticity | Kuzmin A Sandin J Terenius L |
| STANDEN N.B. | Mechanisms that regulate [Ca2+]i following depolarisation in rat systemic arterial smooth muscle cells | 2000 | University of Leicester | Kamishima, T. Davies, N.W. |
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| SOMOGYI P | Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus | 2000 | University of Oxford | Neuroscience | Bergles, D.E. Roberts, J.D.B. Jahr, C.E. |
| SOMOGYI P | Proximally targeted GABAergic synapses and gap junctions synchronize cortical interneurons | 2000 | University of Oxford | Neuroscience | Tamas, G. Buhl, E.H. Lorincz, A. |
| SIM E | Structure of arylamine N-acetyltransferase reveals a catalytic triad | 2000 | University of Oxford | Pharmacogenetics + Toxicology | Sinclair, J.C. Sandy, J. Delgoda, R. |
| SHARP T | Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate in the brain | 2000 | University of Oxford | Neuroscience | Patel, S. Churchill, G.C. Galione, A. |
| SEWARD E.P. | Bidirectional modulation of exocytosis by angiotensin II involves multiple G-protein-regulated transduction pathways in chromaffin cells | 2000 | University of Leicester | Treschemacher A.G. | |
| SEWARD E.P. | P2Y purinoceptors inhibit exocytosis in adrenal chromaffin cells via modulation of voltage-operated calcium channels | 2000 | University of Leicester | Powell A.D. Treschmacher A.G. |
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| Richardson P.J. | Adenosine receptor expression and function in rat striatal cholinergic interneurones. | 2000 | University of Cambridge | Preston, Z. Lee, K Freeman, T.C. |
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| Richardson P.J. | Correlating cell physiology with gene expression in single neurons | 2000 | University of Cambridge | Dixon, A. Lee, K. Bell, M.I. |
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| Ribchester RR | Competition at silent synapses in reinnervated skeletal muscle | 2000 | University of Edinburgh | Neural Plasticity | Costanzo EM Barry JA Ribchester RR |
| Rang H.P. | Bradyzide, a potent non-peptide B(2) bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesia. | 2000 | University College London | Neuropharmacology and neuroscience | Burgess, G. M. Perkins, M. N. Campbell, E. A. |
| Ramage A.G. | Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats. | 2000 | University College London | Neuropharmacology and neuroscience | Wang, Y. Jones, J. F. X. Jeggo, R. D. |
| Poole AW | Evidence of a role for SHP-1 in platelet activation by the collagen receptor glycoprotein VI. | 2000 | University of Bristol | Pasquet,J-M Quek,L Pasquet,S |
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| Pirmohamed M | Association analysis of drug metabolising enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole | 2000 | University of Liverpool | Drug Safety | Alfirevic A Vilar J Stalford A |
| Perretti M | Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules. | 2000 | Queen Mary, University of London | Biochemical Pharmacology | McLean PG Ahluwalia A |
| Perrett D | Optimised separation of endogenous urinary components using cyclodextrin-modified micellar electrokinetic capillary chromatography [In Process Citation] | 2000 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Alfazema LN Howells S |
| Perrett D | Novel three-dimensional capillary electrophoresis system for complex and trace analyis. | 2000 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Hanna M Simpson C |
| Perrett D | Determination of taurine in plasma by capillary zone electrophoresis following derivatisation with fluorescamine [In Process Citation] | 2000 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Kelly MT Fabre H |
| Park BK | Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of a-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts | 2000 | University of Liverpool | Drug Safety | Boocock DJ Maggs JL Brown K |
| Park BK | Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi | 2000 | University of Liverpool | Drug Safety | Henderson CJ Wolf CR Kitteringham N |
| Park BK | Hepatocellular response to chemical stress in CD-1 mice: Induction of early genes and g-glutamylcysteine synthetase | 2000 | University of Liverpool | Drug Safety | Kitteringham NR Powell H Clement YN |
| POMPEO F | Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1-phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activity and | 2000 | University of Oxford | Pharmacogenetics + Toxicology | Bourne, Y. van Heijenoort, J. Fassy, F. |
| POMPEO F | Autophosphorylation of phosphoglucosamine mutase from Escherichia coli | 2000 | University of Oxford | Pharmacogenetics + Toxicology | Jolly, L. van Heijenoort, J. Fassy, F. |
| PAULSEN OKH | Natural patterns of activity and long-tem synaptic plasticity | 2000 | University of Oxford | Neuroscience | Sejnowski, T.J. |
| PATEL S | Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhances the sensitivity of NAADP receptors for their ligand | 2000 | University of Oxford | Integrative Biology | Churchill, G.C. Galione, A. |
| O'Byrne S | Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion. | 2000 | Queen Mary, University of London | Clinical Pharmacology | Forte P Roberts LJ Morrow JD |
| O'Byrne S | Inhibition of platelet aggregation with glyceryl trinitrate and xanthine oxidoreductase. | 2000 | Queen Mary, University of London | Clinical Pharmacology | Shirodaria C Millar T Stevens C |
| Nissim A | Specific inhibition of the reaction between a tumor-inhibitory antibody and Erb-2 receptor by a mimotype derived from a phage display library. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Vaisman N Klapper LN Tirosh B |
| Nissim A | Human single-chain Fv fragments specific for natural killer cell receptors from phage display libraries. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Uchanska-Ziegler B Qiao X Volz A |
| Naisbitt DJ | Plasma cysteine deficiency and decreased reduction of nitrosulfamethoxazole with HIV infection | 2000 | University of Liverpool | Drug Safety | Vilar FJ Stalford AC Wilkins EGL |
| Naisbitt DJ | Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals. | 2000 | University of Liverpool | Drug Safety | Schnyder B Burkhart C Schnyder-Frutig K |
| NAHORSKI S.R. | Lysophosphatidic acid-induced Ca2+ mobilisation requires intracellular sphingosine 1-phosphate production: potential involvement of endogenous Edg-4 receptors | 2000 | University of Leicester | Young K.W. Bootman M.D. Channing D.R. |
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| NAGY Z | Coexisting pathologies in the brain: influence of vascular disease and Parkinson's disease on Alzheimer's pathology in the hippocampus | 2000 | University of Oxford | Neuroscience | Smith, M.Z. Barnetson, L. King, E.M.F. |
| Moss G.W.J. | Structure-activity relationships for the interaction of bovine pancreatic trypsin inhibitor with an intracellular site on a large conductance Ca | 2000 | University College London | Receptors, ion channels and transduction | Favre, I. Goldenberg, D.P. Otlewski, J. |
| Morton A.J. | Mice transgenic for the Huntington's Disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity | 2000 | University of Cambridge | Hickey, M.A. | |
| Morton A.J. | Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's Disease mutation | 2000 | University of Cambridge | Murphy, K.P.S.J. Carter, R.J. Lione. L.A. |
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| Morris RGM | A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimers disease | 2000 | University of Edinburgh | Neural Plasticity | Chen G Chen KS Knox J |
| Mills P G | Atrial fibrillation after coronary artery bypass surgery: a model for preoperative risk stratification. | 2000 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Zaman AG Archbold RA Helft G |
| Millar N.S. | Cloning and heterologous expression of Dalpha4, a Drosophila neuronal nicotinic acetylcholine receptor subunt: identification of an alternative exon influencing the efficiency of subunit assembly. | 2000 | University College London | Receptors, ion channels and transduction | Lansdell, S. J. |
| Michel A.D. | Apparent species differences in the kinetic properties of P2X7 receptors. | 2000 | University of Cambridge | Hibell, A.D. Kidd, E.J. Chessell, I.P. |
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| Mclean P G | Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment [In Process Citation] | 2000 | Queen Mary, University of London | Clinical Pharmacology | D'Amico M Di Filippo C La M |
| McNaughton P.A. | Modulation of the synaptic Ca2+ current in salamander photoreceptors by polyunsaturated fatty acids and retinoids. | 2000 | University of Cambridge | Vellani, V. Reynolds, M.R. |
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| Matthews E.K. | Photosensitizon of pancreatic tumour cells by d -aminolaevulinic acid esters. | 2000 | University of Cambridge | Whitaker, C.J. Battah, S.H. Forsyth, M.J. |
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| Matthews E.K. | A key role for the mitochondrial benzodiazepine receptor in cellular photosensitisation with d-aminolaevulinic acid. | 2000 | University of Cambridge | Mesenholler, M. | |
| Martin SJ | A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease | 2000 | University of Edinburgh | Neural Plasticity | Chen G Chen KS Knox J |
| Martin SJ | Synaptic plasticity and memory: an evaluation of the hypothesis | 2000 | University of Edinburgh | Neural Plasticity | Martin SJ Grimwood P D Morris RGM |
| Marston H | Overexpression of the human VPAC2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice | 2000 | University of Edinburgh | Neuropharmacology | Shen S Spratt C Sheward WJ |
| MacIntyre I | Modulation of the effects of Osteoprotegerin (OPG) Ligand in Human Leukemic Cell Line by OPG and Calcitonin. | 2000 | Queen Mary, University of London | Clinical Pharmacology | Mancini L Moradi-Bidhendi N Brandi ML |
| MacIntyre I | The biphasic effects of nitric oxide in primary rat osteoblasts are cGMP dependent. | 2000 | Queen Mary, University of London | Clinical Pharmacology | Mancini L Moradi-Bidhendi N Becherini L |
| MacCallum P K | Minimum effective intensity of oral anticoagulant therapy in primary prevention of coronary heart disease. | 2000 | Queen Mary, University of London | Experimental Therapeutics | Brennan PJ Meade TW |
| MITCHESON J. | A structural basis for drug-induced long QT syndrome | 2000 | University of Leicester | Chen J. Lin M. Culberson C. |
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| MITCHESON J. | Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel | 2000 | University of Leicester | Chen J. Lin M. Sanguinetti M.C. |
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| MITCHESON J. | Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate | 2000 | University of Leicester | Chen J. Sanguinetti M.C. |
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| MCILHINNEY RAJ | Molecular characterization of two structurally distinct groups of human Homers, generated by extensive alternative splicing | 2000 | University of Oxford | Neuroscience | Soloviev, M.M. Ciruela, F. Chan, W.Y. |
| Lobo M D | Nuclear localization and apoptotic regulation of an amino-terminal. | 2000 | Queen Mary, University of London | Clinical Pharmacology | Zachary I |
| Kozlowski RZ | A novel anionic conductance affects action potential duration in isolated rat ventricular myocytes. | 2000 | University of Bristol | Spencer,CI Uchida,W |
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| Kelly PAT | 7-Nitroindazole reduces cerebral blood flow following chronic nitric oxide synthase inhibition | 2000 | University of Edinburgh | Neuropharmacology | Kelly PAT Ritchie IM McBean DE |
| Kelly JS | Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis | 2000 | University of Edinburgh | Neuropharmacology | Allsopp TE McLuckie J Kerr LE |
| Kelly EP | Arrestin isoforms dictate differential kinetics of A2B adenosine receptor trafficking. | 2000 | University of Bristol | Mundell,SJ Matharu,A-L Benovic,JL |
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| Kabouridis P | The role of lipid rafts in T cell antigen receptor (TCR) signalling. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Janes PW Ley SC Magee AI |
| Kabouridis P | Cholesterol depletion disrupts membrane rafts and modulates the activity of multiple signalling pathways in T cells. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Janzen J Magee AL Ley SC |
| Johnston A | Measurement of sirolimus in whole blood using high-performance liquid chromatography with ultraviolet detection. | 2000 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Lee T Holt DW |
| Johnston A | New approaches to Cyclosporine monitoring raise further concerns about analytical techniques. | 2000 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Holt DW Kahan BD Morris RG |
| Jenkinson D.H. | Compounds that block both intermediate-conductance (IKCa) and small-conductance (SKCa) calcium-activated postassium channels. | 2000 | University College London | Receptors, ion channels and transduction | Malik-Hall, M. Ganellin, C. R. Galanakis, D. |
| Jenkinson D.H. | Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca | 2000 | University College London | Receptors, ion channels and transduction | Campos Rosa. J. Galanakis, D. Piergentili, A. |
| Jane DE | Native NMDA receptors containing NR2A and NR2B subunits have pharmacologically-distinct competitive antagonist binding sites. | 2000 | University of Bristol | Christie,JM Monaghan,DT |
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| Jacobs M. | The nitration of platelet cytosolic proteins during agonist-induced activation of platelets. | 2000 | University College London | Receptors, ion channels and transduction | Naseem, K.M. Low, S.Y. Sabetkar, M. |
| Irvine R.F. | Nuclear targeting of the B isoform of Type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its a-helix 7. | 2000 | University of Cambridge | Ciruela, A. Hinchcliffe, K. A. Divecha, N |
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| Hoffman R | Synthesis of sulphated acrylic polymers and their evaluation as inhibitors of basic fibroblast growth factor dependent cell growth | 2000 | University of Hertfordshire | Adnett JB Hay JN Niederst C |
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| Hladky S.B. | Adjustments for the display of quantized ion channel dwell times in histograms with logarithmic bins. | 2000 | University of Cambridge | Stark, J.A. | |
| Hladky S.B. | Use of membrane vesicles to investigate drug interactions with transporter proteins, P-glycoprotein and multidrug resistance-associated protein. | 2000 | University of Cambridge | Wheeler, R. Neo, S.-Y. Chew, J. |
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| Hinchliffe K.A. | Thrombin stimulation of platelets causes an increase in phosphatidylinositol 5-phosphate revealed by mass assay. | 2000 | University of Cambridge | Morris, J.B. Ciruela, A. Letcher, A. |
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| Hiley C.R. | Hyperpolarisation of rat mesenteric endothelial cells by ATP-sensitive K+ channel openers. | 2000 | University of Cambridge | White, R. | |
| Henderson R.M. | A cell-free system for regulated exocytosis on PC12 cells. | 2000 | University of Cambridge | Avery, J. Ellis, D.J. Lang, T. |
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| Hemming K | A clean and efficient synthesis of 5-(2'-fluoro-2',3'-dimethylbutanyl-3'-yl) substituted 1,2,4-oxadiazoles using silver tetrafluoroborate as a fluorodesulfurization reagent | 2000 | University of Hertfordshire | Morgan DT Smalley RK |
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| Hemming K | A one-pot Aza-Wittig based solution and polymer supported route to amines | 2000 | University of Hertfordshire | Bevan MJ Loukou C Patel SD |
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| Hemming K | A thiazine-S-oxide, Staudinger/Aza-Wittig based synthesis of benzodiazepines and benzothiadiazeoines | 2000 | University of Hertfordshire | Anwar B Grimsey P Krajniewski M |
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| Harmar AJ | Overexpression of the human VPAC2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice | 2000 | University of Edinburgh | Neuropharmacology | Shen S Spratt C Sheward WJ |
| Grant SGN | Proteomic analysis of NMDA receptor-adhesion protein signaling complexes | 2000 | University of Edinburgh | Neural Plasticity | Husi H Ward MA Choudhary JS |
| Goulding N J | Increased apoptosis in U937 cells over-expressing lipocortin 1 (annexin I) [In Process Citation] | 2000 | Queen Mary, University of London | Biochemical Pharmacology | Canaider S Solito E de Coupade C |
| Gould D J | A novel doxycycline inducible autoregulatory plasmid which displays 'on'/'off' regulation suited to gene therapy applications. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Berenstein M Dreja H Ledda F |
| Gould D J | Immuno- and genetic therapy in autoimmune diseases. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Chernajovsky Y Dreja H Daly C |
| Gilroy D W | Cell cycle dependent expression of cyclo-oxygenase 2 in human fibroblasts. | 2000 | Queen Mary, University of London | Biochemical Pharmacology | Saunders MA Sansores-Garcia Wu KK |
| Gibb A.J. | Single channel properties of P2X ATP receptors in outside-out patches from rat hippocampal granule cells. | 2000 | University College London | Neuropharmacology and neuroscience | Wong, A. Y. C. Burnstock, G. |
| Getting S J | Natural and synthetic agonists of the melanocortin receptor type 3 possess anti inflammatory properties. | 2000 | Queen Mary, University of London | Biochemical Pharmacology | Allcock GH Flower RJ Perretti M |
| Gergely F.V. | The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. | 2000 | University of Cambridge | Karlsson, C. Still, I. Cowell, J. |
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| Gergely F.V. | D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo. | 2000 | University of Cambridge | Kidd, D. Jeffers, K. Wakefield, J.A. |
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| Garthwaite J. | Rapid desensitization of the nitric oxide receptor, soluble guanylyl cyclase, underlies diversity of cellular cGMP responses. | 2000 | University College London | Neuropharmacology and neuroscience | Bellamy, T.C. Wood, J. Goodwin, D.A. |
| GRUBB B.D. | Cyclooxygenase-1 is a marker for a sub-population of putative nociceptive neurones in rat dorsal root ganglia | 2000 | University of Leicester | Chopra B. Giblett S. Little J.G. |
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| GALIONE A | Two neuropeptides recruit different messenger pathways to envoke Ca2+ signals in the same cell | 2000 | University of Oxford | Integrative Biology | Burdakov, D. |
| Foreman J.C. | Involvement of kinins in the hyperresponsiveness induced by platelet activating factor in the human nasal airway. | 2000 | University College London | Turner, P. J. Dear, J. W. |
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| Ford W.R. | Influence of b-adrenoceptor tone on the cardioprotective efficacy of adenosine A1 receptor acativation in isolated working rat hearts. | 2000 | University of Cambridge | Jugdutt, B.I. Lopaschuk, G.D. Schulz, R. |
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| Fitzgerald E.M. | Regulation of voltage-dependent calcium channels in rat sensory neurones involves a Ras/mitogen-activated protein kinase pathway. | 2000 | University College London | Neuropharmacology and neuroscience | |
| Ferguson D.R. | Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells. | 2000 | University of Cambridge | Michea, L. Peters, E.M. Andrews, P.M. |
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| Ferguson D.R. | Activation of epithelial Na+ channel activity in the rabbit urinary bladder by cAMP. | 2000 | University of Cambridge | Burton, T.J. Elneil, S. Nelson, C.P. |
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| Feniuk W. | Selective somatostatin sst2 receptor blockade with the novel cyclic octapeptide, CYN-154806. | 2000 | University of Cambridge | Jarvie, E. Luo, J. Humphrey, P.P.A. |
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| Fan T.P.D. | Expression of angiogenic factor thymidine phosphorylase and angiogenesis in human atherosclerosis. | 2000 | University of Cambridge | Boyle, J.J. Wilson, B. Bicknell, R. |
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| FORSYTHE I.D. | Characterisation of inhibitory and excitatory postsynaptic currents of the rat medial superior olive | 2000 | University of Leicester | Smith A.J. Owens S. |
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| Edwardson J.M. | Analysis of the association of syncollin with the membrane of the pancreatic zymogen granule. | 2000 | University of Cambridge | An, S.J. Hansen, N.J. Hodel, A. |
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| EVANS R.J. | The role of positively charged amino acids in ATP recognition by human P2X1 receptors | 2000 | University of Leicester | Ennion S. Hagan S. |
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| EVANS R.J. | P2 receptor mediated control of rat cerebral (pial) microvasculature; contribution of P2X and P2Y receptors | 2000 | University of Leicester | Lewis C.J. Ennion S. |
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| EVANS R.J. | Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors | 2000 | University of Leicester | Mulryan K. Gitterman D.P. Lewis C.J. |
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| EVANS AM | ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor: a primary role for cADPR in hypoxic pulmonary vasoconstriction | 2000 | University of Oxford | Integrative Biology | Wilson, H. L. Dipp, M. Thomas, J.M. |
| Dunn SMJ | Tyrosine 62 of the ?-aminobutyric acid type A receptor | 2000 | University of Bristol | Newell,JG Davies,M Bateson,AN |
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| Donaldson IML | Afferent signals from the extraocular muscles affect the gain of the horizontal vestibulo-ocular reflex in the alert pigeon | 2000 | University of Edinburgh | Neural Plasticity | Donaldson IML Knox PC |
| Donaldson IML | The functions of the proprioceptors of the eye muscles | 2000 | University of Edinburgh | Neural Plasticity | Donaldson IML |
| Dolphin A.C. | Calcium channel beta subunit promotes voltage-dependent inhibition of alpha1B by G betagamma. | 2000 | University College London | Neuropharmacology and neuroscience | Meir, A. Bell, D. C. Stephens, G. J. |
| Dickenson A.H. | Unaltered peripheral excitatory actions of nociceptin contrast with enhanced spinal inhibitory effects after carrageenan inflammation: an electrophysiological study in the rat. | 2000 | University College London | Neuropharmacology and neuroscience | Carpenter, K Vithlani, M. |
| Dickenson A.H. | Warm coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. | 2000 | University College London | Neuropharmacology and neuroscience | Souslova, V. Cesare, P. Ding, Y. |
| DAVIES N.W. | A residue in the intracellular vestibule of the pore is critical for gating and permeation in Ca2+-activated K+ (BKca) channels | 2000 | University of Leicester | Lippiat, J.D. Standen N.B. |
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| Cull-Candy S.G. | Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype. | 2000 | University College London | Neuropharmacology and neuroscience | Liu, S. Q. |
| Cull-Candy S.G. | Identification of subunits contributing to synaptic and extrasynaptic NMDA receptors in Golgi cells of the rat cerebellum. | 2000 | University College London | Neuropharmacology and neuroscience | Misra, C. Brickley, S.G. Farrant, M. |
| Croxtall J D | Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism [In Process Citation] | 2000 | Queen Mary, University of London | Biochemical Pharmacology | Choudhury Q Flower RJ |
| Corder R | Endothelin-2 synthesis is stimulated by the type-1 tumour necrosis factor receptor and cAMP: comparison with endothelin-converting enzyme-1 expression. | 2000 | Queen Mary, University of London | Experimental Therapeutics | Lambert GL Barker S Lees DM |
| Colville-Nash P R | Cyclopentenone prostaglandins-new allies in the war on inflammation [news] | 2000 | Queen Mary, University of London | Biochemical Pharmacology | Willoughby DA Moore AR |
| Coleman JW | Presentation of IFN-g to nitric oxide oxide-producing cells : a novel function for mast cells | 2000 | University of Liverpool | Drug Safety | Brooks B Briggs DM Eastmond NC |
| Coker SJ | Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes | 2000 | University of Liverpool | Tropical Pharmacology | Batey AJ Lightbown ID Diaz ME |
| Chernajovsky Y | Gene therapy for chronic relapsing experimental allergic encephalomyelitis using cells expressing a novel soluble p75 dimeric TNF receptor. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Croxford JL Triantaphyllopoulos KA Neve RM |
| Chatterjee P K | Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. | 2000 | Queen Mary, University of London | Experimental Medicine and Nephrology | Cuzzocrea S Brown PA Zacharowski K |
| Chatterjee P K | Lipoteichoic acid induces delayed protection in the rat heart: a comparison with endotoxin. | 2000 | Queen Mary, University of London | Experimental Medicine and Nephrology | Zacharowski K Frank S Otto M |
| Chatterjee P K | Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo. | 2000 | Queen Mary, University of London | Experimental Medicine and Nephrology | Zacharowski K Cuzzocrea S Otto M |
| Carrier M J | Endothelial dysfunction accompanies a pro-oxidant, pro-diabetic challenge in the insulin resistant, obese Zucker rat in vivo. | 2000 | Queen Mary, University of London | Experimental Therapeutics | Laight DW Desai KM Anggard EE |
| Callingham B.A. | Inhibitory effects of glibenclamide on the contraction of human arterial conduits used in coronary artery bypass surgery | 2000 | University of Cambridge | Crosbie, A.E. Vuylsteke, A. Ritchie, A.J. |
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| CHURCHILL GC | Spatial control of calcium signaling by NAADP diffusion and gradients | 2000 | University of Oxford | Integrative Biology | Galione, A. |
| CHALLISS R.A.J. | Complex involvement of pertussis toxin-sensitive G-proteins in the regulation of type 1alpha metabotropic glutamate receptor signalling in BHK cells | 2000 | University of Leicester | Hermans E. Saunders R. Selkirk J.V. |
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| Brown D.A. | Calcium channel gating and modulation by neurotransmitters depend on cellular compartmentalization. | 2000 | University College London | Neuropharmacology and neuroscience | Delmas, P. Abogadie, F.C. Buckley, N.J. |
| Born G V R | Effects of reserpine on expression of LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo. | 2000 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Shafi S Stepanova IP Fitzsimmons C |
| Bishop-Bailey D | Bisphenol A diglycidyl ether (BADGE) is a PPARgamma agonist in an ECV304 cell line. | 2000 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Hla T Warner TD |
| Berge T. | Translocation-independent dimerization of the EcoK1 endonuclease visualized by atomic force microscopy. | 2000 | University of Cambridge | Ellis, D.J. Dryden, D.T. Edwardson, J.M. |
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| Barnard E.A. | The P2Y1 receptor closes the N-type Ca2+ channel in neurones, with both adenosine trisphosphates and diphosphates as potent agonists. | 2000 | University of Cambridge | Filippov, A.K. Brown, D.A. |
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| Barakat K | Acute myocardial infarction in women: contribution of treatment variables to adverse outcome [In Process Citation] | 2000 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Wilkinson P Suliman A Ranjadayalan |
| BRADING AF | Structural and functional denervation of human detrusor after spinal cord injury | 2000 | University of Oxford | Integrative Biology | Drake, M.J. Hedlund, F. Mills, I.W. |
| BOLAM PB | Relationship of activity in the subthalamic nucleus-globus pallidus network to cortical electroencephalogram | 2000 | University of Oxford | Neuroscience | Magill, P.J. Bevan, M.D. |
| Antoni FA | Molecular diversity of cyclic AMP signalling | 2000 | University of Edinburgh | Neural Plasticity | Antoni FA |
| Antoni FA | Characterisation of human adenylyl cyclase IX reveals inhibition by Ca2+/calcineurin and differential mRNA polyadenylation | 2000 | University of Edinburgh | Neural Plasticity | Paterson JM Smith SM Simpson J |
| Annenkov A E | Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zeta [In Process Citation] | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Chernajovsky Y |
| Annenkov A E | Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritis. | 2000 | Queen Mary, University of London | Bone and Joint Research Unit | Dreja H Chernajovsky Y |
| Anggard E | Evaluation of the postprandial effects of a fast-food meal on human plasma F(2)-isoprostane levels. | 2000 | Queen Mary, University of London | Experimental Therapeutics | Gopaul NK Zacharowski K Halliwell B |
| de Hoz L | Reversible neural inactivation reveals hippocampal participation in several memory processes | 1999 | University of Edinburgh | Neural Plasticity | Riedel G Micheau J Lam AGM |
| Zacharowski K | Reduction of myocardial infarct size with sCR1sLe(x), an alternatively glycosylated form of human soluble complement receptor type 1 (sCR1), possessing sialyl Lewis x. | 1999 | Queen Mary, University of London | Experimental Medicine and Nephrology | Otto M Hafner G Marsh HC |
| Zacharowski K | Selective activation of the prostaglanoid EP(3) receptor reduces myocardial infarct size in rodents | 1999 | Queen Mary, University of London | Experimental Medicine and Nephrology | Olbrich A Piper J Hafner G |
| Zacharowski K | Endotoxin induces a second window of protection in the rat heart as determined by using p-nitro-blue tetrazolium staining, cardiac troponin T release, and histology. | 1999 | Queen Mary, University of London | Experimental Medicine and Nephrology | Otto M Hafner G Chatterjee PK |
| Zacharowski K | Effects of the prostanoid EP3-receptor agonists M+B 28767 and GR 63799X on infarct size caused by regional myocardial ischaemia in the anaesthetized rat. | 1999 | Queen Mary, University of London | Experimental Medicine and Nephrology | Olbrich A Otto M Hafner G |
| Yaqoob M T | Inhibition of CFU-E colony formation in uremic patients with inflammatory disease: role of IFN-gamma and TNF-alpha [see comments] | 1999 | Queen Mary, University of London | Experimental Medicine and Nephrology | Allen DA Breen C Macdougall |
| Wood ER | The global record of memory in hippocampal neuronal activity | 1999 | University of Edinburgh | Neural Plasticity | Wood ER Dudchenko PA Eichenbaum H |
| Wood ER | The hippocampus, memory, and place cells: Is it spatial memory or a memory space? | 1999 | University of Edinburgh | Neural Plasticity | Eichenbaum H Dudchenko PA Wood ER |
| Winyard P G | Simultaneous analysis of nitrite, nitrate and the nicotinamide nucleotides by capillary electrophoresis: application to biochemical studies and human extracellular fluids. | 1999 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Davies CA Perrett D Zhang Z |
| Winyard P G | Activation of NF-kappaB in human osteoblasts by stimulators of bone resorption. | 1999 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Ali NN Gilston V |
| Willis D. | Evidence that inducible cyclooxygenase may have anti-inflammatory properties. | 1999 | University College London | Receptors, ion channels and transduction | Gilroy, D. Colville-Nash, P. Paul-Clark, M. |
| Whittle B J | Potentiation of cytokine induced iNOS expression in the human intestinal epithelial cell line, DLD-1, by cyclic AMP. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Cavicchi M |
| Whittle B J | Endogenous nitric oxide in the maintenance of rat microvascular integrity against widespread plasma leakage following abdominal laparotomy. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Laszlo F |
| Whittle B J | Regulation of induction of nitric oxide synthase and the inhibitory actions of dexamethasone in the human intestinal epithelial cell line, Caco-2: influence of cell differentiation. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Cavicchi M |
| Whelan CJ | Reactive oxygen species generation and histamine release by activated mast cells: modulation by nitric oxide synthase inhibition | 1999 | University of Hertfordshire | Brooks A C Purcell W M |
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| Whelan CJ | A comparison of the inhibitory effects of budesonide, beclomethasone dipropionate, dexamethasone, hydrocortisone and tixocortol pivalate on cytokine release from leukocytes recovered from human bronchoalveolar lavage fluid | 1999 | University of Hertfordshire | Payne A Planquois J M |
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| Warner T D | Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: consequences for nonsteroidal antiinflammatory drug efficacy. | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Hamilton LC Mitchell JA Tomlinson AM |
| Warner T D | Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis [published erratum appears in Proc Natl Acad Sci U S A 1999 Aug 17;96(17):9666] | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Giuliano F Vojnovic I Bukasa A |
| Warner T D | Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme. | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Woods M Mitchell JA Wood EG |
| Waring M.J. | Reactivity of guanine at m5CpG steps in DNA: evidence for electronic effects transmitted through the base pairs. | 1999 | University of Cambridge | Das, A. Tang, K.S. Gopalakrishnan, S. |
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| Waring M.J. | Demethylation of thymine residues affects DNA cleavage by endonucleases but not sequence recognition by drugs. | 1999 | University of Cambridge | Bailly, C. Crow, S. Minnock, A. |
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| Ward SA | Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum | 1999 | University of Liverpool | Tropical Pharmacology | Bray PG Janneh O Raynes KJ |
| Walley TJ | The General Practice Research Database | 1999 | University of Liverpool | Prescribing Research Group | Mantgani A |
| WILLARS G.B. | Pivotal role for the cytoplasmic carboxyl-terminal tail of a nonmammalian gonadotropin-releasing hormone receptor in cell surface expression, ligand binding, and receptor phosphorylation and internalization | 1999 | University of Leicester | Blomenroehr, M. Heding A. Sellar, R. |
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| WILLARS G.B. | Receptor phosphorylation does not mediate cross-talk between muscarinic M3- and bradykinin B2 receptors. | 1999 | University of Leicester | Mueller-Esterl, W. Nahorski, S.R. |
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| WILLARS G.B. | Lack of a C-terminal tail in the mammalian gonadotropin -releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization | 1999 | University of Leicester | Heding A. Vrecl M. Sellar R. |
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| Venkateswarlu K | EGF-and NGF-stimulated translocation of cytohesin-1 to the plasma membrane of PC12 cells requires PI 3-kinase activation and a functional cytohesin-1 PH domain. | 1999 | University of Bristol | Gunn-Moore,FJ Tavar Cullen,PJ |
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| Vane J | Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs. | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Simmons DL Botting RM Robertson PM |
| Thorn P. | The role of Ca2+ feedback in shaping InsP3-evoked Ca2+ signals in mouse pancreatic acinar cells. | 1999 | University of Cambridge | Kidd, J.F. Fogarty, K.E. Tuft, R.A. |
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| Thiemermann C | Identification of copper/zinc superoxide dismutase as a novel nitric oxide-regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats. | 1999 | Queen Mary, University of London | Experimental Medicine and Nephrology | Frank S Zacharowski K Wray GM |
| Taylor C.W. | Lateral inhibition of inositol 1,4,5-trisphosphate receptors by cytosolic Ca2+. | 1999 | University of Cambridge | Adkins, C.E. | |
| TOBIN A.B. | Activation of the mitogen-activated protein kinase pathway by a Gq/11 coupled muscarinic receptor is independent of receptor internalisation | 1999 | University of Leicester | Budd D.C. Rae A. |
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| TOBIN A.B. | Cross-talk between m3-muscarinic and beta2-adrenergic receptors at the level of receptor phosphorylation and desensitisation | 1999 | University of Leicester | Budd D.C. Challiss R.A.J. Young K.W. |
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| TERRAR DA | An antagonist of cADP-ribose inhibits arrhythmogenic oscillations of intracellular Ca2+ in heart cells | 1999 | University of Oxford | Integrative Biology | Rakovic, S. Cui, Y. Iino, S. |
| Stocker M. | An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons. | 1999 | University College London | Receptors, ion channels and transduction | Krause, M. Pedarzani, P. |
| Stocker M. | Heteromeric assembly of Kv9.3 with Kv2.1: Effect on the state-dependence of inactivation | 1999 | University College London | Receptors, ion channels and transduction | Kerschensteiner, D. |
| Stocker M. | Subunit assembly and domain analysis of electrically silent K+ channel alpha-subunits of the rat Kv9 subfamily. | 1999 | University College London | Receptors, ion channels and transduction | Hellwig, M. Kerschensteiner, D. |
| Stanford S.C. | Modulation of sibutramine-induced increases in extracellular noradrenaline concentration in rat frontal cortex and hypothalamus by alpha2-adrenoceptors. | 1999 | University College London | Neuropharmacology and neuroscience | Wortley, K.E. Heal, D.J. |
| Smith P.A. | Direct effects of tolbutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic b-cells. | 1999 | University of Cambridge | Proks, P. Moorhouse, A. |
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| Smith P.A. | Quantal analysis of 5-hydroxytryptamine release from mouse pancreatic b-cells. | 1999 | University of Cambridge | Proks, P. Ashcroft, F.M. |
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| Sitsapesan RMA | DIDS, DBDS and suramin cause similar modifications to cardiac ryanodine receptor function. | 1999 | University of Bristol | ||
| Shen S | Vectors and YACs comprising an IRES | 1999 | University of Edinburgh | Neuropharmacology | Shen S Schedl A Harmar AJ |
| Shen S | Structure of the human VIPR2 gene for vasoactive intestinal peptide receptor type 2 | 1999 | University of Edinburgh | Neuropharmacology | Lutz EM Shen S Mackay M |
| Sharkey J | A rat model of Endothelin-3-induced middle cerebral artery occlusion with controlled reperfusion | 1999 | University of Edinburgh | Neuropharmacology | Henshall DC Butcher SP Sharkey J |
| Sharkey J | Recommendations for standards regarding preclinical neuroprotective and restorative drug development | 1999 | University of Edinburgh | Neuropharmacology | Finklestein SP Fisher M Furlan AJ |
| Sellers L.A. | Prolonged activation of extracellular signal-regulated kinase by a protein kinase C-dependent and N17Ras-insensitive mechanism mediates the proliferative response of Gi/o-coupled somatostatin sst4 receptors. | 1999 | University of Cambridge | ||
| Sellers L.A. | Activated G protein-coupled receptor induces tyrosine phosphorylation of STAT3 and agonist-selective serine phosphorylation via sustained stimulation of mitogen-activated protein kinase. | 1999 | University of Cambridge | Feniuk, W. Humphrey, P.P.A. Lauder, H. |
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| STANFIELD P.R. | The possible role of disulphiode bond in forming functional Kir2.1 potassium channels | 1999 | University of Leicester | Leyland, M.L. Dart C. Spencer P.J. |
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| SIM E | Cloning and characterisation of arylamine N-acetyltransferase genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: increased expression results in isoniazid resistance | 1999 | University of Oxford | Pharmacogenetics + Toxicology | Payton, M. Auty, R. Delgoda, R. |
| SANTORO B | The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels | 1999 | University of Oxford | Neuroscience | Tibbs, G.R. |
| Roberts PJ | Group I mGlu receptors potentiate synaptosomal [3H]glutamate release independently of exogenously applied arachidonic acid. | 1999 | University of Bristol | Reid,ME Toms,NJ Bedingfield,JS |
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| Ribchester RR | Co-regulation of synaptic efficacy at stable polyneuronally innervated neuromuscular junctions in reinnervated rat muscle | 1999 | University of Edinburgh | Neural Plasticity | Costanzo EM Barry JA Ribchester RR |
| Rang H.P. | Noxious heat activates all capsaicin-sensitive and also a sub-population of capsaicin-insensitive dorsal root ganglion neurons. | 1999 | University College London | Neuropharmacology and neuroscience | Nagy, I. |
| Rang H.P. | Similarities and differences between the responses of rat sensory neurons to noxious heat and capsaicin. | 1999 | University College London | Neuropharmacology and neuroscience | Nagy, I. |
| Ramage A.G. | Evidence for a role for central 5-HT2B as well as 5-HT2A receptors in cardiovascular regulation in anaesthetized rats. | 1999 | University College London | Neuropharmacology and neuroscience | Knowles, I. D. |
| ROEPER J | The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels | 1999 | University of Oxford | Neuroscience | Liss, B. Neu, A. |
| ROEPER J | Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic in midbrain neurons | 1999 | University of Oxford | Neuroscience | Liss, B. Bruns, A. |
| Poole AW | Glycoprotein GP Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor g-chain, Fyn and Lyn, to activate human platelets. | 1999 | University of Bristol | Falati,S Edmead,CE |
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| Poole AW | Thrombin-induced association of SHP-2 with multiple tyrosine-phosphorylated proteins in human platelets. | 1999 | University of Bristol | Edmead,CE Crosby,D Southcott,MJG |
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| Plane F | Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. | 1999 | University of Bristol | Doughty,JM Langton,PD |
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| Pitcher J.A. | Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. | 1999 | University College London | Receptors, ion channels and transduction | Tesmer, J. J. Freeman, J. L. Capel, W. D. |
| Pirmohamed M | Induction of metabolism-dependent and | 1999 | University of Liverpool | Drug Safety | Naisbitt DJ Williams DP Park BK |
| Pirmohamed M | The effect of the CYP2C9 genetic polymorphisms on sulphamethoxazole N-hydroxylation | 1999 | University of Liverpool | Drug Safety | Gill HJ Kitteringham NR Park BK |
| Park BK | Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether | 1999 | University of Liverpool | Drug Safety | O'Neill PM Searle NL Kan KW |
| POMPEO F | Crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily | 1999 | University of Oxford | Pharmacogenetics + Toxicology | Brown, K. Dixon, S. Mengin-Lecreulx, D. |
| PATEL S | Co-ordination of Ca2+ signals by endothelial-derived nitric oxide in the intact liver | 1999 | University of Oxford | Integrative Biology | Robb Gaspers, L.D. Stellato, K.A. Shon, M. |
| Olverman HJ | Pyrazolopyridine derivatives act as competitive antagonists of brain adenosine A1 receptors: [35S]GTPgS binding studies | 1999 | University of Edinburgh | Neuropharmacology | Ito H Maemoto T Akahane A |
| Olverman HJ | Effects of the specific serotonin reuptake inhibitor, citalopram upon local cerebral blood flow and glucose utilisation in the rat | 1999 | University of Edinburgh | Neuropharmacology | McBean DE Ritchie IM Olverman HJ |
| Nurrish S. | Serotonin inhibition of synaptic transmission: Galpha0 decreases the abundance of UNC-13 at release sites. | 1999 | University College London | Neuropharmacology and neuroscience | Segalat, L. Kaplan, J.M. |
| Nurrish S. | Facilitation of synaptic transmission by EGL-30 Gqalpha and EGL-8 PlC beta: DAG binding to UNC-13 is required to stimulate acetylcholine release. | 1999 | University College London | Neuropharmacology and neuroscience | Lackner, M.R. Kaplan, J.M. |
| NICOTERA PL | ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation | 1999 | University of Leicester | Volbracht, C. Leist M. |
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| NICOTERA PL | Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity | 1999 | University of Leicester | Hansson, O Petersen, A Leist, M |
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| NAHORSKI S.R. | Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors | 1999 | University of Leicester | Davis R.J. Challiss R.A.J. |
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| NAGY Z | Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease | 1999 | University of Oxford | Neuroscience | Esiri, M.M. Smith, M.Z. Barnetson, L. |
| Murrell-Lagnado R.D. | Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels | 1999 | University of Cambridge | Ho, I.H.M. | |
| Murrell-Lagnado R.D. | Molecular determinants for sodium-dependent activation of G protein-gated K+ channels. | 1999 | University of Cambridge | Ho, I.H.M. | |
| Murrell-Lagnado R.D. | Identification of amino acids within the P2X2 receptor C-terminus that regulate desensitization. | 1999 | University of Cambridge | Smith, F.M. Humphrey, P.P.A. |
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| Munroe P B | Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Olgunturk RO Fryns JP Maldergem LV |
| Moss S.J. | GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton. | 1999 | University College London | Receptors, ion channels and transduction | Wang, H. W. Bedford, F. K. Brandon, N. J. |
| Moss S.J. | The protein MAP-IB links GABAC receptors to the cytoskeleton at retinal synapses. | 1999 | University College London | Receptors, ion channels and transduction | Hanley, J. G. Koulen, P. Bedford, F. K. |
| Morton A.J. | Characterisation of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. | 1999 | University of Cambridge | Carter, R.J. Lione, L.A. Humby, T. |
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| Morris RGM | The functional neuroanatomy of comprehension and memory: the importance of prior knowledge | 1999 | University of Edinburgh | Neural Plasticity | Maguire EA Frith CD Morris RGM |
| Molleman A | CB1 cannabinoid receptor-mediated activation of K+ current in DDT1 MF-2 cells is entirely dependent on the presence of extracellular Ca2+ | 1999 | University of Hertfordshire | Begg M Nelemans SA |
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| Molleman A | Reactive oxygen species generation by non-immunological mast cell activation: modulation by the synthetic cannabinoid CP55,940 | 1999 | University of Hertfordshire | Brooks A C Gustafsson F Whelan C J |
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| Millar N.S. | Upregulation of cell-surface alpha4beta2 neuronal nicotinic receptors by lower temperature and expression of chimeric subunits. | 1999 | University College London | Receptors, ion channels and transduction | Cooper, S . T. Harkness, P. C. Baker, E. R. |
| Michel A.D. | Ionic effects on human recombinant P2X7 receptor function. | 1999 | University of Cambridge | Chessell, I.P. Humphrey, P.P.A. |
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| Mclean P G | Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des-Arg9bradykinin-induced coronary vasodilation. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Perretti M Ahluwalia A |
| McQueen DS | Impaired cholinergic dilator response of resistance arteries isolated from patients with Raynauds disease | 1999 | University of Edinburgh | Neuropharmacology | Smith PJW Ferro CJ McQueen DS |
| McNaughton P.A. | Specific involvement of PKC-e in sensitization of the neuronal response to painful heat. | 1999 | University of Cambridge | Cesare, P. Dekker, L.V. Sardini, A. |
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| Martin SJ | Reversible neural inactivation reveals hippocampal participation in several memory processes | 1999 | University of Edinburgh | Neural Plasticity | Riedel G Micheau J Lam AGM |
| Marston H | Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat | 1999 | University of Edinburgh | Neuropharmacology | Marston HM Reid ME Lawrence JA |
| MacIntyre I | Developmental regulation of nitric oxide synthase expression in rat skeletal bone. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Hukkanen MVJ Platts LA Fernandez De Marticorena I |
| MITCHESON J. | An investigation of the role played by the E-4031-sensitive (rapid delayed rectifier) potassium current in isolated rabbit atrioventricular nodal and ventricular myocytes | 1999 | University of Leicester | Hancox J.C. | |
| MCILHINNEY RAJ | Characterization of the dimerization of metabotropic glutamate receptors using an N-terminal truncation of mGluR1 alpha | 1999 | University of Oxford | Neuroscience | Robbins, M.J. Ciruela, F. Rhodes, A. |
| Lobo M D | Differential regulation of extracellular signal-regulated protein kinases (ERKs) 1 and 2 by cAMP and dissociation of ERK inhibition from anti-mitogenic effects in rabbit vascular smooth muscle cells. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Cospedal R Zachary I |
| La M | Effects of pyrogallol, hydroquinone and duroquinone on responses to nitrergic nerve stimulation and NO in the rat anococcygeus muscle. | 1999 | Queen Mary, University of London | Biochemical Pharmacology | Rand MJ |
| Kozlowski RZ | Relaxation of endothelin-1 induced pulmonary arterial constriction by niflumic acid and NPPB: mechanism(s) independent of chloride channel block. | 1999 | University of Bristol | Kato,K Evans,AM |
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| Kitteringham NR | Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity | 1999 | University of Liverpool | Drug Safety | Hough SJ Gill HJ Pirmohamed M |
| Khoo SH | Adenoviruses from human immunodeficiency virus-infected individuals, including two strains that represent new candidate serotypes Ad50 and Ad51 of subspecies B1 and D respectively | 1999 | University of Liverpool | Pharmacology of HIV Disease | De Jong JC Hierholzer JC van Doornum GJJ |
| Kelly JS | Alzheimer's disease: the tacrine legacy | 1999 | University of Edinburgh | Neuropharmacology | Kelly JS |
| Kelly EP | Selective reduction in A2 adenosine receptor desensitization following antisense-induced suppression of G protein-coupled receptor kinase 2 expression. | 1999 | University of Bristol | Willets,JM Parent,J-L Benovic,JL |
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| Johnston A | Effects of recombinent human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion. | 1999 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Comacho-Hubner C Woods KA Miraki-Moud F |
| Johnston A | Therapeutic drug monitoring of immunosuppressant drugs. | 1999 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Holt DW |
| Jenkinson D.H. | Differences in the actions of some blockers of the calcium-activated potassium permeability in mammalian red cells. | 1999 | University College London | Receptors, ion channels and transduction | Benton, D. C. H. Roxburgh, C. J. Ganellin, C. R. |
| Jane DE | Pharmacological agents acting at subtypes of metabotropic glutamate receptors. | 1999 | University of Bristol | Schoepp,DD Monn,JA |
|
| Jane DE | Antagonist activity of a-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells. | 1999 | University of Bristol | Doherty,AJ Collingridge,GL |
|
| Irvine R.F. | PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase. | 1999 | University of Cambridge | Schell, M.J. Letcher, A.J. Brearley, C.A. |
|
| Irvine R.F. | Nuclei contain two differentially regulated pools of diacylglycerol. | 1999 | University of Cambridge | D'Santos, C. Clarke, J.H. Divecha, N. |
|
| Humphrey P.P.A. | Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO-K1 cells and involvement of Gas proteins. | 1999 | University of Cambridge | Carruthers, A.M. Warner, A.J. Michel, A.D. |
|
| Hoffman R | The use of proteases as prognostic markers for the healing of venous leg ulcers | 1999 | University of Hertfordshire | Noble J Eagle M |
|
| Hinchliffe K.A. | Regulation of type IIa phosphatidylinositol phosphate kinase localisation by the protein kinase CK2. | 1999 | University of Cambridge | Ciruela, A. Letcher, A. Divecha, N. |
|
| Henderson R.M. | Direct observation of DNA translocation and cleavage by the EcoKI endonuclease using atomic force microscopy. | 1999 | University of Cambridge | Ellis, D.J. Dryden, D.T. Berge, T. |
|
| Haycox AR | Clinical guidelines | 1999 | University of Liverpool | Prescribing Research Group | Bagust A Walley T |
| Haycox AR | The North Staffordshire Community beds study | 1999 | University of Liverpool | Prescribing Research Group | Unsworth L Allen K Hodgson R |
| Harmar AJ | Presence of multiple functional polyadenylation signals and a single nucleotide polymorphism in the 3 untranslated region of the human serotonin transporter gene,Battersby S,Ogilvie AD,Blackwood DHR,5,Journal of Neurochemistry,72,1384-1388, | 1999 | University of Edinburgh | Neuropharmacology | Battersby S Ogilvie AD Blackwood DHR |
| Grootveld M | The role of N-acetylcysteine in protecting synovial fluid biomolecules against radiolytically-mediated oxidative damage: a high field proton NMR study. | 1999 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Silwood CJ Lynch EJ Patel IY |
| Grootveld M | Examination of the metabolic status of rat air pouch inflammatory exudate by high field proton NMR spectroscopy. | 1999 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Claxson A Chander C Earl J |
| Goyal M | Spoligotyping in Molecular epidemiology of Tuberculosis in Ghana | 1999 | University of Hertfordshire | Lawn SD Afful B Acheampong JW |
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| Goyal M | Genotypic analysis of Mycobacterium tuberculosis from medieval human remains | 1999 | University of Hertfordshire | Taylor GM Legge AJ Shaw RJ |
|
| Goulding N J | The inhibitory effect of dexamethasone on lymphocyte adhesion molecule expression and intercellular aggregation is not mediated by lipocortin 1. | 1999 | Queen Mary, University of London | Biochemical Pharmacology | Ogbourn S Pipitone N Biagini P |
| Gould D J | Immunotherapy of auto-immune diseases by gene transfer [In Process Citation] | 1999 | Queen Mary, University of London | Bone and Joint Research Unit | Chernajovsky Y Annenkov A Dreja H |
| Gilroy D W | Inducible cyclooxygenase may have anti-inflammatory properties [see comments] | 1999 | Queen Mary, University of London | Biochemical Pharmacology | Colville-Nash PR Willis D Chivers J |
| Getting S J | POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. | 1999 | Queen Mary, University of London | Biochemical Pharmacology | Gibbs L Clark AJ Flower RJ |
| Genazzani A.A. | Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons | 1999 | University of Cambridge | Carafoli, E. Guerini, D. |
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| GRUBB B.D. | Characterization of cultured dorsal root ganglion neuron P2X receptors | 1999 | University of Leicester | Evans R.J | |
| GRUBB B.D. | The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an upregulation of cyclooxygenase-2 in the spinal cord | 1999 | University of Leicester | Ebersberger A. Willingale H.L. Gardiner N.J. |
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| GALIONE A | Co-ordination of agonist-induced calcium signalling patterns by NAADP in pancreatic acinar cells | 1999 | University of Oxford | Integrative Biology | Cancela, J.M. Churchill, G.C. |
| Forte P | Measurement of nitric oxide synthesis in humans using L-[15N2]arginine. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Smith LM Milne E Benjamin N |
| Forte P | Nitric oxide synthesis in patients with infective gastroenteritis. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Dykhuizen RS Milne E McKenzie |
| Foreman J.C. | The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells. | 1999 | University College London | Receptors, ion channels and transduction | Tatla, S. Woodhead, V. Chain, B. M. |
| Flower R J | Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC. | 1999 | Queen Mary, University of London | Biochemical Pharmacology | Tailor A Tomlinson A Salas A |
| Fitzgerald E.M. | cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS. | 1999 | University College London | Neuropharmacology and neuroscience | Okuse, K. Wood, J. N. Dolphin, A. C. |
| Finlayson K | Pyrazolopyridine derivatives act as competitive antagonists of brain adenosine A1 receptors:[35S]GTPgS binding studies | 1999 | University of Edinburgh | Neuropharmacology | Ito H Maemoto T Akahane A |
| Ferguson D.R. | Urothelial function. | 1999 | University of Cambridge | ||
| Edwardson J.M. | Identification of SNAREs involved in regulated exocytosis in the pancreatic acinar cell. | 1999 | University of Cambridge | Hansen, N.J., Antonin, W. |
|
| Edwards IG | Enhanced in vitro neurotoxicity of artemisinin derivatives in the presence of haem | 1999 | University of Liverpool | Tropical Pharmacology | Smith SL Fishwick J McLean WG |
| EVANS AM | Relaxation of endothelin-1-induced pulmonary arterial constriction by niflumic acid and NPPB: Mechanism(s) independent of chloride channel block | 1999 | University of Oxford | Integrative Biology | Kato, K. Kozlowski, R.Z. |
| EMPTAGE NJ | Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines | 1999 | University of Oxford | Neuroscience | Bliss, T.V.P. Fine, A. |
| EMPTAGE NJ | Fluorescent imaging of synaptic transmission at single synapses in the central nervous system | 1999 | University of Oxford | Neuroscience | Bliss, T. Fine, A. |
| Dunn SMJ | Mutagenesis of the rat a1 subunit of the ?-aminobutyric acid receptor reveals the importance of residue 101 in determining the allosteric effects of benzodiazepine site ligands. | 1999 | University of Bristol | Davies,M Muntoni,AL Lambert,JJ |
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| Dolphin A.C. | Identification of residues in the N terminus of alpha1B critical for inhibition of the voltage-dependent calcium channel by G betagamma. | 1999 | University College London | Neuropharmacology and neuroscience | Canti, C. Page, K. M. Stephens G. J. |
| Dickenson A.H. | The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. | 1999 | University College London | Neuropharmacology and neuroscience | Akopian, A N. Souslova, V. England, S. |
| DART C. | Direct block of native and cloned (Kir2.1) inward rectifier K+ channels by chloroethylclonidine | 1999 | University of Leicester | Barrett-Jolley, R. Standen N.B. |
|
| D'Cruz D | Lymphocyte activation markers and von Willebrand factor antigen in Wegener's granulomatosis: potential markers for disease activity. | 1999 | Queen Mary, University of London | Bone and Joint Research Unit | Direskeneli H Khamashta M Hughes GVR |
| Corder R | The expression of endothelin-1 and endothelin-converting enzyme-1 are independently regulated in bovine aortic endothelial cells. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Barker S |
| Corder R | Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Barker DM |
| Coleman JW | Reciprocal effects of interleukin-4 and interferon-g on immuno-globulin E-mediated mast cell degranulation: a role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate | 1999 | University of Liverpool | Drug Safety | DeSchoolmeester ML Eastmond NC Dearman RJ |
| Coker SJ | Potential interactions between iloprost and SIN-1 on platelet aggregation and myocardial infarct size | 1999 | University of Liverpool | Tropical Pharmacology | Aitchison KA |
| Chernajovsky Y | Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis. | 1999 | Queen Mary, University of London | Bone and Joint Research Unit | Rabinovitch G Daly G Dreja H |
| Chernajovsky Y | Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy. | 1999 | Queen Mary, University of London | Bone and Joint Research Unit | Triantaphyllopoulos KA Williams RO Tailor H |
| Chatterjee P K | Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress. | 1999 | Queen Mary, University of London | Experimental Medicine and Nephrology | Cuzzocrea S Thiemermann C |
| Chan W L | A proinflammatory role for IL-18 in rheumatoid arthritis [see comments] | 1999 | Queen Mary, University of London | Bone and Joint Research Unit | Gracie JA Forsey RJ Gilmour A |
| Carrier M J | Pro-oxidant challenge in vivo provokes the onset of NIDDM in the insulin resistant obese Zucker rat. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Laight DW Desai KM Gopaul NK |
| Callingham B.A. | Changes in reactivity of the digital artery of the fallow deer, Dama dama, in summer and winter. | 1999 | University of Cambridge | Milton, A.S. Carr, G. Luby, C. |
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| COLEMAN MP | The major brain isoform of Kif1b lacks the putative mitochondria-binding domain | 1999 | University of Oxford | Neuroscience | Conforti, L. Buckmaster, E.A. Tarlton, A. |
| CHALLISS R.A.J. | Inhibition of N-linked glycosylation of the human type 1alpha metabotropic glutamate receptor by tunicamycin: effects on cell-surface expression and function | 1999 | University of Leicester | Mody N. Hermans E. Nahorski S.R. |
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| CAPOGNA M | Miniature synaptic events maintain dendritic spines via AMPA receptor activation | 1999 | University of Oxford | Neuroscience | McKinney, R A Durr, R. Gahwiler, B.H. |
| Brown D.A. | Two types of K+ channel subunit, Erg1 and KCNQ2/3, contribute to the M-like current in a mammalian neuronal cell. | 1999 | University College London | Neuropharmacology and neuroscience | Selyanko, A.A. Hadley, J.K. Wood, I.C. |
| Breckenridge AM | Quattro Steering Committee (A. Breckenridge, Chairman). A randomised trial comparing regimens of four reverse transcriptase inhibitors given together or cyclically in HIV-1 Infection | 1999 | University of Liverpool | Pharmacology of HIV Disease | Babiker A Back DJ Blatchford N |
| Bishop-Bailey D | Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Hla T |
| Berge T. | Patterned regrowth of n-GaAs by molecular beam epitaxy using arsenic passivation | 1999 | University of Cambridge | Heinlen, C. Fimland, B-O. Grepstad, J.K. |
|
| Berge T. | Investigation of protein partnerships using atomic force microscopy. | 1999 | University of Cambridge | Ellis, D.J. Edwardson, J.M. Henderson, R.M. |
|
| Benjamin N | Effect of nitric-oxide-generating system on microcirculatory blood flow in skin of patients with severe Raynaud's syndrome: a randomised trial. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Tucker AT Pearson RM Cooke ED |
| Barrand M.A. | Functional and molecular characterization of a volume-sensitive chloride current in rat brain endothelial cells. | 1999 | University of Cambridge | Weikersthal von, S.F. Hladky, S.B. |
|
| Barakat K | Getting to the heart of the matter. | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Pyne D Rothman MT |
| Barakat K | Platelet IIb/IIIa antagonists followed by delayed stent implantation. A new treatment for vein graft lesions containing massive thrombus. | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Robinson N Dymond D |
| Barakat K | How should age affect management of acute myocardial infarction? A prospective cohort study [see comments] | 1999 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Wilkinson P Deaner A Fluck D |
| Back DJ | Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. | 1999 | University of Liverpool | Pharmacology of HIV Disease | Profit L Eagling VA |
| Back DJ | The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1. | 1999 | University of Liverpool | Pharmacology of HIV Disease | Moore KHP Barrett JE Shaw S |
| Back DJ | Interaction of sildenafil and indinavir when co-administered to HIV-positive patients | 1999 | University of Liverpool | Pharmacology of HIV Disease | Merry C Barry MG Ryan M |
| BRUNSKILL N.J. | Lysophosphatidic acid-induced calcium mobilization and proliferation in kidney proximal tubular cells | 1999 | University of Leicester | Dixon R.J. Young K.W. |
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| BRUNSKILL N.J. | Lysophosphatidic acid-induced proliferation in opossum kidney proximal tubular cells: Role of PI 3-kinase and ERK | 1999 | University of Leicester | Dixon R.J. | |
| BRUNSKILL N.J. | Activation of mitogenic pathways by albumin in kidney proximal tubule epithelial cells: Implications for the pathophysiology of proteinuric states | 1999 | University of Leicester | Dixon R.J. | |
| BLANK J.L. | MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases | 1999 | University of Leicester | Deacon, K. | |
| BLANK J.L. | Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G protein-linked muscarine acetylcholine receptors | 1999 | University of Leicester | Wylie P.G. Challiss, R.A.J. |
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| Arbuthnott GW | Double anterograde tracing of outputs from adjacent barrel columns of rat somatosensory cortex. Neostriatal projection patterns and terminal ultrastructure | 1999 | University of Edinburgh | Neural Plasticity | Wright AK Hutton EAM Norrie L |
| Antoni FA | Molecular components of large conductance calcium-activated potassium (BK) channels in mouse pituitary corticostropes | 1999 | University of Edinburgh | Neural Plasticity | Shipston MJ Duncan RR Clark AG |
| Anggard E | F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Nourooz-Zadeh Liu EH Yhlen B |
| Anggard E | Photoplethysmographic assessment of pulse wave reflection: blunted response to endothelium-dependent beta2-adrenergic vasodilation in type II diabetes mellitus. | 1999 | Queen Mary, University of London | Experimental Therapeutics | Chowienczyk PJ Kelly RP MacCallum H |
| Ahluwalia A | B1 receptors as a new inflammatory target. Could this B the 1?. | 1999 | Queen Mary, University of London | Clinical Pharmacology | Perretti |
| Ahluwalia A | Cholinergic Contraction is Altered in nNOS Knockouts: Co-operative Modulation of Neural Bronchoconstriction by nNOS and COX | 1999 | Queen Mary, University of London | Clinical Pharmacology | Kakuyama M Rodrigo J Vallance P |
| van Veen H.W. | A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. | 1998 | University of Cambridge | Callaghan, R. Soceneantu, L. Sardini, A. |
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| de Hoz L | Contingent versus incidental context processing during conditioning: dissociation after excitotoxic hippocampal plus dentate gyrus lesions | 1998 | University of Edinburgh | Neural Plasticity | Good M de Hoz L Morris RGM |
| Young J.M. | Dual effects of histamine and substance P on intracellular calcium levels in human U373 MG astrocytoma cells: role of protein kinase C. | 1998 | University of Cambridge | Young, K.W. Pinnock, R.D. Gibson, W.J. |
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| Young J.M. | Ca2+/calmodulin-mediated regulation of agonist-induced sequestration of Gq protein-coupled histamine H1-receptors in human U373 MG astrocytoma cells. | 1998 | University of Cambridge | Hishinuma, S. Naiki, A. Tsuga, H. |
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| Wyllie DJA | Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors | 1998 | University of Edinburgh | Neuropharmacology | Wyllie DJA Behe P Colquhoun D |
| Wyllie DJA | Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors | 1998 | University of Edinburgh | Neuropharmacology | Anson LC Chen PE Wyllie DJA |
| Willis D. | Inhibition of indicible nitric oxide synthase by peroxisome proliferator-activated receptor agonist: Correlation with induction of heme oxygenase 1. | 1998 | University College London | Receptors, ion channels and transduction | Colville-Nash, P.R. Qureshi, S.S. Willoughby, D.A. |
| White R | The actions of the cannabinoid receptor antagonist, SR141716A, in the rat isolated mesenteric artery. | 1998 | University of Cambridge | Hiley, C.R. | |
| White R | Effects of K+ channel openers on relaxations to nitric oxide and endothelium-derived hyperpolarizing factor in rat mesenteric artery. | 1998 | University of Cambridge | Hiley, C.R. | |
| Warner T D | Regulation of Cyclo-oxygenase Gene Expression in Rat Smooth Muscle Cells by Catalase. | 1998 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Chen G Kamal M Hannon R |
| Waring M.J. | The exocyclic groups of DNA modulate the affinity and positioning of the histone octamer. | 1998 | University of Cambridge | Buttinelli, M. Minnock, A. Panetta, G. |
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| Ward SA | Access to heamatin: the basis of chloroquine resistance | 1998 | University of Liverpool | Tropical Pharmacology | Bray PG Mungthin M Ridley RG |
| Wall MJ | Development of the quantal properties of evoked and spontaneous synaptic currents at a brain synapse | 1998 | University of Bristol | Usowicz,MM | |
| WILLARS G.B. | Acute desensitization of phospholipase C-coupled muscarinic M3 receptors but not gonadotropin-releasing hormone receptors co-expressed in alphaT3-1 cells: implications for mechanisms of rapid desensitization | 1998 | University of Leicester | McArdle, C.A. Nahorski, S.R. |
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| WATSON SP | Collagen receptor signalling in platelets: extending the role of the ITAM | 1998 | University of Oxford | Integrative Biology | Gibbins, J. |
| Venkateswarlu K | Insulin dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase. | 1998 | University of Bristol | Oatey,PB Tavar Cullen,PJ |
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| Venkateswarlu K | The N-terminal membrane domain of yeast NADPH-cytochrome P450 Oxidoreductase is not required for catalytic activity in sterol biosynthesis or in reconstitution of CYP activity. | 1998 | University of Bristol | Lamb,DC Kelly,DE Kelly,SL |
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| Vane J | Cyclooxygenases 1 and 2. | 1998 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Bakhle YS Botting RM |
| Vane J | Anti-inflammatory drugs and their mechanism of action. | 1998 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Botting RM |
| Usowicz MM | Development of the quantal properties of evoked and spontaneous synaptic currents at a brain synapse | 1998 | University of Bristol | Wall,MJ | |
| Timmis A D | Frequency and prognostic implications of conduction defects in acute myocardial infarction since the introduction of thrombolytic therapy. | 1998 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Archbold RA Sayer JW Ray S |
| Timmis A D | Circadian activity of the endogenous fibrinolytic system in stable coronary artery disease: effects of beta-adrenoreceptor blockers and angiotensin-converting enzyme inhibitors. | 1998 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Sayer JW Gutteridge C Syndercombe-Court D |
| Thiemermann C | Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ failure. | 1998 | Queen Mary, University of London | Experimental Medicine and Nephrology | Kengatharan KM De Kimpe S Robson C |
| Smith P.A. | Inhibition of the ATP-sensitive potassium channel from mouse pancreatic b-cells by surfactants. | 1998 | University of Cambridge | Proks, P. | |
| Skehel PA | Dendritic localization of mRNAs | 1998 | University of Edinburgh | Neural Plasticity | Kuhl D Skehel P |
| Sihra T.S. | An essential role for a small synaptic vesicle-associated phosphatidylinositol 4-kinase in neurotransmitter release. | 1998 | University College London | Neuropharmacology and neuroscience | Wiedemann, C. Schafer, T. Burger, M. M. |
| Sihra T.S. | Presynaptic GABA B receptor modulation of glutamate exocytosis from rat cerebrocortical nerve terminals: receptor decoupling by protein kinase C. | 1998 | University College London | Neuropharmacology and neuroscience | Perkinton, M. S. |
| Schoepfer R. | Identification of amino acid residues of the NR2A subunit which control glutamate potency in recombinant NR1/NR2A NMDA receptors. | 1998 | University College London | Receptors, ion channels and transduction | Anson, L. C. Chen, P. E. Wyllie, D. J. A. |
| Sandin JSBE | Hippocampal dynorphin B injections impair spatial learning in rats: A k-opioid receptor-mediated effect | 1998 | University of Edinburgh | Neural Plasticity | Sandin J Nylander I Georgieva J |
| Sandin JSBE | Modulation of acetylcholine and serotonin transmission by galanin | 1998 | University of Edinburgh | Neural Plasticity | Ogren SO Schott PA Kehr J |
| STANDEN N.B. | ATP-sensitive K+ channel activation by calcitonin gene-related peptide and protein kinase A in pig coronary arterial smooth muscle | 1998 | University of Leicester | Wellman, G.C. Quayle, J.M. |
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| SOMOGYI P | Increased number of synaptic GABA (A) receptors underlies potentiation at hippocampal inhibitory synapses | 1998 | University of Oxford | Neuroscience | Nusser, Z. Hajos, N. Mody, I. |
| SMITH AD | Folate, vitamin B12 and serum total homocysteine levels in confirmed Alzheimer's disease | 1998 | University of Oxford | Neuroscience | Clarke, R. Jobst, K.A. Refsum, H. |
| SMITH AD | Abnormal function of potassium channels in platelets of patients with Alzheimer's disease | 1998 | University of Oxford | Neuroscience | de Silva, H.A. Aronson, J.K. Grahame-Smith, D.G. |
| SANTORO B | Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain | 1998 | University of Oxford | Neuroscience | Liu, D.T. Yao, H. Bartsch, D. |
| Richardson P.J. | Identification of an ATP sensitive potassium channel current in rat striatal cholinergic interneurones. | 1998 | University of Cambridge | Lee, K. Dixon, A Freeman, T.C. |
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| Richardson P.J. | Expression profiling of single cells using three prime end amplification (TPEA) PCR. | 1998 | University of Cambridge | Dixon, A. Lee, K. Carter, N.P. |
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| Ribchester RR | Enhancement of spontaneous transmitter release at neonatal mouse neuromuscular junctions by the glial cell line derived neurotrophic factor (GDNF) | 1998 | University of Edinburgh | Neural Plasticity | Ribchester RR Thomson D Haddow LJ |
| Ramage A.G. | The central action of the 5-HT2 receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cardiac inotropy and vascular resistance in the anaesthetized cat. | 1998 | University College London | Neuropharmacology and neuroscience | Daly, M. de B. |
| ROEPER J | NIP domain prevents N-type inactivation in voltage-gated potassium channels | 1998 | University of Oxford | Neuroscience | Sewing, S. Zhang, Y. Sommer, T. |
| Pitcher J.A. | G protein-coupled receptor kinases. | 1998 | University College London | Receptors, ion channels and transduction | Freedman, N. J. Lefkowitz, R. J. |
| Pitcher J.A. | The G protein-coupled receptor kinase is a microtubule-associated protein kinase that phosphorylates tubulin. | 1998 | University College London | Receptors, ion channels and transduction | Hall, R. A. Daaka, Y. Zhang, J. |
| Perretti M | Promoting detachment of neurophils adherent to murine post-capillary venules to control inflammation: Effect of lipocortin 1. | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Lim LHK Solito E Russo-Marie F |
| POMPEO F | Probing the role of cysteine residues in glucosamine-1-phosphate acetyltransferase activity of the bifunctional GlmU protein from Escherichia coli: site-directed mutagenesis and characterization of the mutant enzymes | 1998 | University of Oxford | Pharmacogenetics + Toxicology | van Heijenoort, J. Mengin-Lecreulx, D. |
| PAULSEN OKH | A model of hippocampal memory encoding and retrieval: GABAergic control of synaptic plasticity | 1998 | University of Oxford | Neuroscience | Moser, E.I. |
| PAULSEN OKH | Cholinergic induction of network oscillations at 40Hz in the hippocampus in vitro | 1998 | University of Oxford | Neuroscience | Fisahn, A. Pike, F.G. Buhl, E.H. |
| PAULSEN OKH | Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo | 1998 | University of Oxford | Neuroscience | Sprenge, R. Suchanek, B. Amico, C. |
| PATEL S | Decorin activates the epidermal growth factor receptor and elevates cytosolic Ca2+ in A431 carcinoma cells | 1998 | University of Oxford | Integrative Biology | Santra, M. McQuillan, D.J. Iozzo, R.V. |
| Olverman HJ | Pharmacological characterisation of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques | 1998 | University of Edinburgh | Neuropharmacology | Marston HM Finlayson K Maemoto T |
| O'Byrne S | Genetics of hypertension. Therapeutic implications. | 1998 | Queen Mary, University of London | Clinical Pharmacology | Caulfield M |
| Naisbitt DJ | Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs | 1998 | University of Liverpool | Drug Safety | Williams DP Maggs JL Pirmohamed M |
| NICOTERA PL | 1-methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation and neuronal apoptosis | 1998 | University of Leicester | Leist, M. Volbracht, C. Fava, E. |
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| Munroe P B | Mutations in the palmitoyl-protein thioesterase gene (PPT; CLN1) causing juvenile neuronal ceroid lipofuscinosis with granular osmiophilic deposits [published erratum appears in Hum Mol Genet 1998 Apr;7(4):765] | 1998 | Queen Mary, University of London | Clinical Pharmacology | Mitchison HM Hofmann SL Becerra CH |
| Moss S.J. | Intracellular retention of recombinant GABAB receptors. | 1998 | University College London | Receptors, ion channels and transduction | Couve, A. Filippov, A. K. Connolly, C.N. |
| Morton A.J. | Dopamine modulates the susceptibiity of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease. | 1998 | University of Cambridge | Reynolds, D.S. Carter, R.J. |
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| Morris RGM | Impaired spatial learning after saturation of long-term potentiation | 1998 | University of Edinburgh | Neural Plasticity | Moser EI Krobert KA Moser M-B |
| Molleman A | Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption | 1998 | University of Hertfordshire | Bailey C P Little H J |
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| Molleman A | Chronic ethanol administration alters neuronal activity in VTA neurones after cessation of withdrawal hyperexcitability | 1998 | University of Hertfordshire | Bailey C P Manley S J Watson |
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| Michel A.D. | Cibacron blue allosterically modulates the rat P2X4 receptor. | 1998 | University of Cambridge | Miller, K.J. Chessell, I.P. Humphrey, P.P.A. |
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| McQueen DS | Activation of P2X receptors for adenosine triphosphate evokes cardiorespiratory reflexes in anaesthetized rats | 1998 | University of Edinburgh | Neuropharmacology | McQueen DS Bond SM Moores C |
| McQueen DS | P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint | 1998 | University of Edinburgh | Neuropharmacology | Dowd E McQueen DS Chessell IP |
| Marston H | Pharmacological characterization of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques | 1998 | University of Edinburgh | Neuropharmacology | Marston HM Finlayson K Maemoto T |
| Marshall I. | Alpha1A-adrenoceptor mediated contraction of rat prostatic vas deferens and the involvement of ryanodine stores and Ca | 1998 | University College London | Receptors, ion channels and transduction | Burt, R. P. Chapple, C. R. |
| Marshall I. | Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. | 1998 | University College London | Receptors, ion channels and transduction | Wisskirchen, F. M. Burt, R. P. |
| Marrion NV | Selective activation of calcium-activated potassium channels by colocalized calcium channels in hippocampal neurons | 1998 | University of Bristol | Tavalin,SJ | |
| Marrion NV | A novel lipid-anchored A-kinase anchoring protein facilitates cAMP-responsive membrane events | 1998 | University of Bristol | Fraser,IDC Tavalin,SJ Lester,LB |
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| MacIntyre I | Nitric oxide superoxide and peroxynitrite modulate osteoclast activity. | 1998 | Queen Mary, University of London | Clinical Pharmacology | Mancini L Moradi-Bidhendi N Brandi ML |
| MacCallum P K | Clinical characteristics determining the mode of presentation in patients with acute coronary syndromes. | 1998 | Queen Mary, University of London | Experimental Therapeutics | Kennon S Suliman A Ranjadayalan K |
| MacCallum P K | Sex differences in the determinants of fibrinolytic activity. | 1998 | Queen Mary, University of London | Experimental Therapeutics | Cooper JA Howarth DJ Meade TW |
| MacCallum P K | Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. | 1998 | Queen Mary, University of London | Experimental Therapeutics | Poller L Shiach CR Johansen AM |
| Larkman PM | Characterization of 5-HT-sensitive potassium conductances in neonatal rat facial motoneurones in vitro | 1998 | University of Edinburgh | Neuropharmacology | Larkman PM Kelly JS |
| La M | Human soluble guanylate cyclase: functional expression and revised isoenzyme family. | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Weeger M Zabel U Schmidt HHW |
| La M | Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase. | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Bommel HM Reif A Frohlich LG |
| Kozlowski RZ | Functional evidence for a novel suramin-insensitive pyrimidine receptor in rat small pulmonary arteries. | 1998 | University of Bristol | Hartley,SA Kato,K |
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| Koenig J.A. | Fates of endocytosed somatostatin sst2 receptors and associated agonists. | 1998 | University of Cambridge | Kaur, R. Edwardson, J.M. Dodgeon, I. |
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| Koenig J.A. | Involvement of receptor cycling and receptor reserve in resensitization of muscarinic responses in SH-SY5Y human neuroblastoma cells. | 1998 | University of Cambridge | Szekeres, P.G. Edwardson, J.M. |
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| Kitteringham NR | Expression of cytochrome P4502E1 in human liver: assessment by mRNA, genotype and phenotype | 1998 | University of Liverpool | Drug Safety | Powell H Pirmohamed M Smith DA |
| Kidd B L | Increased capsaicin-induced secondary hyperalgesia as a marker of abnormal sensory activity in patients with fibromyalgia. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Morris V Cruwys S |
| Khoo SH | Influenza-like episodes in HIV-positive patients: the role of viral and atypical infections | 1998 | University of Liverpool | Pharmacology of HIV Disease | Hajia M Klapper PE Wilkins EGL |
| Kelly PAT | Intracerebral fetal raphe implants normalize hippocampal function but not cerebrovascular control in serotonin-depleted adult rat brain | 1998 | University of Edinburgh | Neuropharmacology | Kelly PAT McBean DE Ritchie IM |
| Kelly JS | New use of aminopiperazine derivatives | 1998 | University of Edinburgh | Neuropharmacology | Marston HM Kelly JS |
| Kelly EP | Somatostatin receptor desensitization in NG108-15 cells: a consequence of receptor sequestration? | 1998 | University of Bristol | Beaumont,VL Hepworth,MB Luty,JS |
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| Kabouridis P | Inhibition of TCR/CD3-mediated signaling by a mutant of the hematopoietically expressed G16 GTP-binding protein. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Zhou J Stanners J Han H |
| Jane DE | Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. | 1998 | University of Bristol | Thomas,NK Hawkins,LM Miller,JC |
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| Jacobs M. | 3-Nitrotyrosine in the proteins of human plasma determined by an ELISA method. | 1998 | University College London | Receptors, ion channels and transduction | Khan, J. Brennan, D.M. Bradley, N. |
| Ismail FMD | Mechanism of formation of benzene-2-thiol | 1998 | University of Hertfordshire | Isaccs NS Hilton MJ Coulson M |
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| Ismail FMD | Novel aryl-bis-quinolones with antimalarial activity in vivo | 1998 | University of Hertfordshire | Dascombe MJ Carr PJ Merette SAM |
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| Humphrey P.P.A. | Blockade of human P2X7 receptor function with a monoclonal antibody. | 1998 | University of Cambridge | Buell, G. Chessell, I.P. Michel, A.D. |
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| Hoffman R | Wound fluid from venous leg ulcers degrades plasminogen and reduces plasmin generation by keratinocytes | 1998 | University of Hertfordshire | Starkey S Coad J |
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| Hladky S.B. | Streaming potentials in gramicidin channels measured with ion selective microelectrodes. | 1998 | University of Cambridge | Tripathi, S. | |
| Hinchliffe K.A. | PIPkins, their substrates and their products; new functions for old enzymes. | 1998 | University of Cambridge | Ciruela, A. Irvine, R.F. |
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| Hinchliffe K.A. | Regulation of PtdIns 4-P 5-kinase C by thrombin-stimulated changes in its phosphorylation state in human platelets. | 1998 | University of Cambridge | Irvine, R.F. Divecha, N. |
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| Hiley C.R. | The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. | 1998 | University of Cambridge | White, R. | |
| Henderson G | ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain | 1998 | University of Bristol | Khakh,BS | |
| Henderson G | Somatostatin receptor desensitization in NG108-15 cells: a consequence of receptor sequestration? | 1998 | University of Bristol | Beaumont,VL Hepworth,MB Luty,JS |
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| Henderson G | Glycine and GABAA receptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by | 1998 | University of Bristol | Grudt,TJ | |
| Haycox AR | Cost-effectiveness of treatment for GORD in clinical practice | 1998 | University of Liverpool | Prescribing Research Group | Eggleston A Wigerinck A Huijghebgert S |
| Haycox AR | An integrated national pharmaceutical policy for the United Kingdom? | 1998 | University of Liverpool | Prescribing Research Group | Walley T Earl-Slater A Bagust A |
| Harmar AJ | Nomenclature of Receptors for Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide | 1998 | University of Edinburgh | Neuropharmacology | Harmar AJ Arimura A Gozes I |
| Grootveld M | In vivo absorption, metabolism, and urinary excretion of alpha,beta-unsaturated aldehydes in experimental animals. Relevance to the development of cardiovascular diseases by the dietary ingestion of thermally stressed polyunsaturate-rich culinary oils. | 1998 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Atherton MD Sheerin AN Hawkes J |
| Grant SGN | Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein | 1998 | University of Edinburgh | Neural Plasticity | Migaud M Charlesworth P Dempster M |
| Grant SGN | Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo | 1998 | University of Edinburgh | Neural Plasticity | Sprengel R Suchanek B Amico C |
| Goyal M | Pulmonary tuberculosis in Harare, Zimbabwe: analysis by spoligotyping | 1998 | University of Hertfordshire | Heyderman RS Roberts P Ushewokunze S |
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| Goulding N J | Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Euzger HS Butt SK Perretti M |
| Gould D J | Potentiation of TNF-alpha toxicity by conjugation with ricin A-chain. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Foxwell BM Feldmann M Chernajovsky Y |
| Gilroy D W | Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Tomlinson A Willoughby DA |
| Gilroy D W | Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation [see comments] | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Tomlinson A Willoughby DA |
| Forte P | Evidence for a difference in nitric oxide biosynthesis between healthy women and men. | 1998 | Queen Mary, University of London | Clinical Pharmacology | Kneale BJ Milne E Chowienczyk PJ |
| Foreman J.C. | Cutaneous responses to endothelin-1 and histamine in patients with vibration white finger. | 1998 | University College London | Receptors, ion channels and transduction | Dowd, P. M. Goldsmith, P. C. Chopra, S. |
| Ford W.R. | K(ATP)-channel activation: Effects on myocardial recovery from ischaemia and role in the cardioprotective response to adenosine A1-receptor stimulation. | 1998 | University of Cambridge | Lopaschuk, G.D. Schulz, R. Clanachan, A.S. |
|
| Ford W.R. | Intrinsic ANG II type 1 receptor stimulation contributes to recovery of postischemic mechanical function. | 1998 | University of Cambridge | Clanachan, A.S. Lopaschuk, G.D. Schulz, R. |
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| Finlayson K | Pharmacological characterization of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques | 1998 | University of Edinburgh | Neuropharmacology | Marston HM Finlayson K Maemoto T |
| Feniuk W. | Differential effects of somatostatin and angiopeptin on cell proliferation. | 1998 | University of Cambridge | Alderton, F. Lauder, H. Fan, T.P.D. |
|
| Feniuk W. | Differential agonist activity of somatostatin and L-362855 at human recombinant sst4 receptors. | 1998 | University of Cambridge | Smalley, K.S.M. Humphrey, P.P.A. |
|
| Fan T.P.D. | Quantification of the repair process involved in the repair of a cell monolayer using an in vitro model of mechanical injury. | 1998 | University of Cambridge | Lauder, H. Frost, E.E. Hiley, C.R. |
|
| FORSYTHE I.D. | Contrasting Ca2+ channel subtypes at cell bodies and synaptic terminals of rat anterioventral cochlear bushy neurones | 1998 | University of Leicester | Doughty, J.M. Barnes-Davies M., Rusznak Z., |
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| FORSYTHE I.D. | Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse | 1998 | University of Leicester | Tsujimoto T. Barnes-Davies M. Cuttle M.F. |
|
| Edwardson J.M. | The relationship between agonist intrinsic activity and the rate of endocytosis of muscarinic receptors in a human neuroblastoma cell line. | 1998 | University of Cambridge | Szekeres, P.G. Koenig, J.A. |
|
| Edwards IG | Synthesis and antimalarial activity of sixteen dispiro-1,2,4,5-tetroxane analogs of WR 148999 | 1998 | University of Liverpool | Tropical Pharmacology | Vennerstrom J Dong Y Andersen SL |
| Edwards IG | Assessment of the effect of malaria infection on hepatic clearance of dihydroartemisinin using rat liver perfusions and microsomes | 1998 | University of Liverpool | Tropical Pharmacology | Batty KT Ilett KF Powell SM |
| EVANS R.J. | 2',3'-0-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP) a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels | 1998 | University of Leicester | Lewis C.J. Surprenant A. |
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| Donaldson IML | Signals of eye position and velocity in the first-order afferents from pigeon extraocular muscles | 1998 | University of Edinburgh | Neural Plasticity | Fahy FL Donaldson IML |
| Dolphin A.C. | Identification of the amino terminus of neuronal Ca2+ channel alpha1 subunits, alpha 1B and alpha 1E, as an essential determinant of G-protein modulation. | 1998 | University College London | Neuropharmacology and neuroscience | Page, K.M. Canti, C. Stephens, G. J. |
| Dolphin A.C. | Known calcium channel alpha1 subunits can form low threshold small conductance channels with similarities to native T-type channels. | 1998 | University College London | Neuropharmacology and neuroscience | Meir, A. |
| Dickenson A.H. | Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors. | 1998 | University College London | Neuropharmacology and neuroscience | Bannon, A W Decker, M. W. Holladay, M. W. |
| DAVIES N.W. | Block of cloned BKCa channels (rSlo) expressed in HEK 293 cells by N-methyl D-glucamine | 1998 | University of Leicester | Lippiat, J.D. Standen N.B. |
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| DART C. | The dependence of Ag+-block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter | 1998 | University of Leicester | Leyland, M.L. Barrett-Jolley, R.A. Shelton P.A. |
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| DART C. | The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis | 1998 | University of Leicester | Leyland, M.L. Spencer P.J. Stanfield P.R. |
|
| D'Cruz D | Antibodies to beta2-glycoprotein I: a potential marker for clinical features of antiphospholipid antibody syndrome in patients with systemic lupus erythematosus. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Sanfilippo SS Khamashta MA Atsumi T |
| Croxtall J D | Inhibitory effect of peptides derived from the N-terminus of lipocortin 1 on arachidonic acid release and proliferation in the A549 cell line: identification of E-Q-E-Y-V as a crucial component. | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Choudhury Q Flower RJ |
| Colville-Nash P R | Inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: correlation with induction of heme oxygenase 1. | 1998 | Queen Mary, University of London | Biochemical Pharmacology | Qureshi SS Willis D Willoughby DA |
| Colquhoun D. | Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. | 1998 | University College London | Receptors, ion channels and transduction | Wyllie, D.J.A. Behe, P. |
| Colquhoun D. | Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. | 1998 | University College London | Receptors, ion channels and transduction | Anson, L. C. Chen, P. E. Wyllie, D. J. A. |
| Colquhoun D. | Binding, gating, affinity and efficacy. The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. | 1998 | University College London | Receptors, ion channels and transduction | |
| Chernajovsky Y | Mutation of proline 211 reduces shedding of the human p75 TNF receptor. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Herman C |
| Chan W L | Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Xu D McSorley SJ Tetley L |
| Chan W L | Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Xu D Leung BP Hunter D |
| Chan W L | Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Xu D Leung BP Huang F |
| Caulfield M J | Absence of linkage of the epithelial sodium channel to hypertension in black Caribbeans. | 1998 | Queen Mary, University of London | Clinical Pharmacology | Munroe PB Strautnieks SS Farrall M |
| Caulfield M J | Evaluation of the Angiotensinogen Locus in Human Essential Hypertension: A European Study. | 1998 | Queen Mary, University of London | Clinical Pharmacology | Brand E Chatelain N Keavney B |
| Carter T.D. | Membrane capacitance changes induced by thrombin and calcium in single endothelial cells cultured from human umbilical vein. | 1998 | University College London | Receptors, ion channels and transduction | Zupancic, G. Smith, S.M. Wheeler-Jones, C. |
| Carrier M J | Investigation of oxidant stress and vasodepression to glyceryl trinitrate in the obese Zucker rat in vivo. | 1998 | Queen Mary, University of London | Experimental Therapeutics | Laight DW Kengatharan KM Gopaul NK |
| Carrier M J | Reactive oxygen species regulate macrophage scavenger receptor type I, but not type II, in the human monocytic cell line THP-1. | 1998 | Queen Mary, University of London | Experimental Therapeutics | De Kimpe SJ Anggard EE |
| Callingham B.A. | Monoamine oxidase activities in human cystic and colonic arteries - influence of age. | 1998 | University of Cambridge | Figueiredo, I.V. Martinez Coscolla, A. Cotrim, M.D. |
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| CHALLISS R.A.J. | Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells | 1998 | University of Leicester | Willars, G.B Nahorski, S.R. |
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| CAVIERES J.D. | Photoinactivation of fluorescein isothiocyanate-modified Na,K-ATPase by 2'(3')-0-(2,4,6-trinitrophenyl)8-azidoadenosine 5'-diphosphate. Abolition of E1 and E2 partial reactions by sequential block of high and low-affinity nucleotide sites | 1998 | University of Leicester | Ward, D.G. | |
| CAVIERES J.D. | Affinity labeling of two nucleotide sites on Na,K-ATPase using 2 | 1998 | University of Leicester | Ward D.G. | |
| Brown D.A. | The alpha subunit of Gq contributes to muscarinic inhibition of the M-type potassium current in sympathetic neurons. | 1998 | University College London | Neuropharmacology and neuroscience | Haley, J.E. Abogadie, F.C. Delmas, P. |
| Breckenridge AM | Pharmacokinetics of combination therapy with nelfinavir plus nevirapine. | 1998 | University of Liverpool | Pharmacology of HIV Disease | Merry C Barry MG Mulcahy F |
| Bishop-Bailey D | Differential induction of cyclooxygenase-2 in human arterial and venous smooth muscle: role of endogenous prostanoids. | 1998 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Pepper JR Larkin SW Mitchell JA |
| Berge T. | Preconditioning of c-plane sapphire for GaN molecular beam epitaxy by electron cyclotron resonance plasma nitridation | 1998 | University of Cambridge | Heinlein, C. Grepstad, J.K. Einfeldt, S. |
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| Benjamin N | Helicobacter pylori is killed by nitrite under acidic conditions. | 1998 | Queen Mary, University of London | Clinical Pharmacology | Dykhuizen A Fraser A McKenzie |
| Barrand M.A. | Multidrug resistance related transport proteins in isolated human brain microvessels and in cells cultured from these isolates. | 1998 | University of Cambridge | Seetharaman, S. Maskell, L. Scheper, R.J. |
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| Barnard E.A. | Molecular cloning and characterisation of the rat P2Y4 receptor. | 1998 | University of Cambridge | Webb, T.E. Henderson, D.J. Roberts, J.A. |
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| Back DJ | Effect of ribavirin on zidovudine efficacy and toxicity in vitro: A concentration dependent interaction | 1998 | University of Liverpool | Pharmacology of HIV Disease | Sim SM Hoggard PG Sales SM |
| BRUNSKILL N.J. | Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase | 1998 | University of Leicester | Stuart J. Tobin A.B. Walls J. |
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| Arbuthnott GW | Effects of potassium channel blockers on synaptic plasticity in the corticostriatal pathway | 1998 | University of Edinburgh | Neural Plasticity | Wickens JR Mckenzie D Costanzo E |
| Antoni FA | Ca2+/calcineurin-inhibited adenylyl cyclase highly abundant in forebrain regions important for learning and memory | 1998 | University of Edinburgh | Neural Plasticity | Antoni FA Palkovits M Simpson J |
| Annenkov A E | Loss of original antigenic specificity in T cell hybridomas transduced with a chimeric receptor containing single-chain Fv of an anti-collagen antibody and Fc epsilonRI-signaling gamma subunit. | 1998 | Queen Mary, University of London | Bone and Joint Research Unit | Moyes SP Eshhar Z Mageed RA |
| Young J.M. | Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]-g-aminobutyric acid release from depolarisation-stimulated slices of rat substantia nigra pars reticulata. | 1997 | University of Cambridge | Garcia, M. Floran, B. Arias-Montano, J.A. |
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| Winstanley PA | Chlorproguanil-dapsone: an effective treatment for uncomplicated falciparum malaria. | 1997 | University of Liverpool | Tropical Pharmacology | Watkins W Hatcher J Lowe B |
| Willoughby D A | The inhibition of colon-26 adenocarcinoma development and angiogenesis by topical diclofenac in 2.5% hyaluronan. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Seed MP Brown JR Freemantle CN |
| Willoughby D A | The codependence of angiogenesis and chronic inflammation. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Jackson JR Seed MP Kircher CH |
| Wall MJ | Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum | 1997 | University of Bristol | Usowicz,MM | |
| Usowicz MM | Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum | 1997 | University of Bristol | Wall,MJ | |
| Thomas P. | Modulation of stimulus-secretion coupling in single rat gonadotrophs. | 1997 | University of Cambridge | Waring, D.W. | |
| Thiemermann C | Effect of calpain inhibitor I, an inhibitor of the proteolysis of I kappa B, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat. | 1997 | Queen Mary, University of London | Experimental Medicine and Nephrology | Ruetten H |
| Thiemermann C | Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle. | 1997 | Queen Mary, University of London | Experimental Medicine and Nephrology | Bowes J Myint FP Vane JR |
| Taylor C.W. | Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity. | 1997 | University of Cambridge | Marchant, J.S. | |
| Taylor C.W. | Ca2+-independent inhibition of inositol trisphosphate receptors by calmodulin: Redistribution of calmodulin as a possible means of regulating Ca2+ mobilization. | 1997 | University of Cambridge | Patel, S. Morris, S.A. Adkins, C.E. |
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| TOBIN A.B. | Stimulus-Dependent Phosphorylation of G-Protein Coupled Receptors By Casein Kinase 1alpha | 1997 | University of Leicester | Totty N.F. Sterlin A.E. Nahorski S.R. |
|
| Smith P.A. | Electrogenic arginine transport mediates stimulus-secretion coupling in mouse pancreatic b-cells | 1997 | University of Cambridge | Sakura, H. Coles, B. Gummerson, N. |
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| Sharkey J | Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism | 1997 | University of Edinburgh | Neuropharmacology | Butcher SP Henshall DC Teramura Y |
| Sellers L.A. | Somatostatin sst5 inhibition of receptor mediated regeneration of rat aortic vascular smooth muscle cells. | 1997 | University of Cambridge | Lauder, H. Fan, T.-P.D. Feniuk, W. |
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| Schoepfer R. | Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel. behaviour. | 1997 | University College London | Receptors, ion channels and transduction | Sivilotti, L. G. McNeil, D. K. Lewis, T. M |
| Sandin JSBE | Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats | 1997 | University of Edinburgh | Neural Plasticity | Sandin J Georgieva J Schott PA |
| STANFIELD P.R. | Membrane currents influencing action potential latency in granule neurons of the rat cochlear nucleus | 1997 | University of Leicester | Rusznak Z. Forsythe I.D. Brew H.M. |
|
| STANDEN N.B. | ATP-sensitive and inwardly rectifying potassium channels in smooth muscle | 1997 | University of Leicester | Quayle, J.M. Nelson, M.T. |
|
| STANDEN N.B. | Angiotensin II inhibition of ATP-sensitive K+ currents in rat arterial smooth muscle cells through protein kinase C | 1997 | University of Leicester | Kubo, M. Quayle, J.M. |
|
| SMITH AD | Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease | 1997 | University of Oxford | Neuroscience | Lehmann, D.J. Johnston, C. |
| SIM E | Mapping AAC1, AAC2 and AACP, the genes for arylamine N-acetyltranferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours | 1997 | University of Oxford | Pharmacogenetics + Toxicology | Matas, N. Thygesen, P. Stacey, M. |
| SANTORO B | Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels | 1997 | University of Oxford | Neuroscience | Grant, S.G.N. Bartsch, D. Kandel, E.R. |
| Roberts PJ | Inhibition of AMPA receptor-stimulated 57Co2+ influx by D- and L-2-amino-4-phosphonobutanoic acid (L-AP4) and L-serine-O-phosphate (L-SOP) in cultured cerebellar granule cells | 1997 | University of Bristol | Toms,NJ Hawkins,LM |
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| Ribchester RR | Elimination of motor nerve terminals in neonatal mice expressing a gene for slow Wallerian degeneration (C57Bl/Wlds) | 1997 | University of Edinburgh | Neural Plasticity | Parson SH Mackintosh CL Ribchester RR |
| Rang H.P. | Capsaicin and carbon dioxide act by distinct mechanisms on sensory nerve terminals in the cat cornea. | 1997 | University College London | Neuropharmacology and neuroscience | Chen, X. Belmonte, C. |
| Poole AW | The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen | 1997 | University of Bristol | Gibbins,JM Turner,M Van Vugt,MJ |
|
| Plane F | Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery | 1997 | University of Bristol | Cohen,RA Najibi,S Garland,CJ |
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| Perrett D | Analysis of coricosteroids in biofluids by capillary electrochromatography with gradient elution. | 1997 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Taylor MR Teale P Westwood SA |
| PATEL S | Ca2+ -independent inhibition of inositol trisphosphate receptors by calmodulin: redistribtuion as a possible means of regulating Ca2+ mobilization | 1997 | University of Oxford | Integrative Biology | Morris, S.A. Adkins, C.E. O'Beirne, G. |
| Olverman HJ | Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists | 1997 | University of Edinburgh | Neuropharmacology | Maemoto T Finlayson K Olverman HJ |
| O'Byrne S | ACE inhibition: postsynaptic adrenergic sympatholytic action in men [see comments] | 1997 | Queen Mary, University of London | Clinical Pharmacology | Lyons D Roy S Swift CG |
| Nissim A | Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform. | 1997 | Queen Mary, University of London | Bone and Joint Research Unit | Neri D Carnemolla B Leprini A |
| Naisbitt DJ | Disposition of amodiaquine and related antimalarials in human neutrophils: Implications for drug design. | 1997 | University of Liverpool | Drug Safety | Ruscoe JE Williams DP O'Neill PM |
| NICOTERA PL | The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown | 1997 | University of Leicester | Gohring, F. Schwab, B.L. Leist, M. |
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| NAHORSKI S.R. | Enhanced type 1alpha metabotropic glutamate receptor-stimulated phosphoinositide signalling after pertussis toxin treatment | 1997 | University of Leicester | Carruthers A.M. Challiss R.A.J. Mistry R. |
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| NAGY Z | Cell cycle markers in the hippocampus in Alzhemier's disease | 1997 | University of Oxford | Neuroscience | Esiri, M.M. Cato, A.M. Smith, A.D. |
| NAGY Z | The effects of additional pathology on the cognitive deficit in Alzheimer's disease | 1997 | University of Oxford | Neuroscience | Esiri, M.M. Jobst, K.A. Morris, J.H. |
| Murrell-Lagnado R.D. | Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channels. | 1997 | University of Cambridge | Woodward, R. Stevens, E.B. |
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| Munroe P B | Spectrum of mutations in the Batten disease gene, CLN3. | 1997 | Queen Mary, University of London | Clinical Pharmacology | Mitchison HM O'Rawe AM Anderson JW |
| Morris RGM | Synaptic tagging and long term potentiation | 1997 | University of Edinburgh | Neural Plasticity | Frey U Morris RGM |
| Mills P G | The role of signal averaged P wave duration and serum magnesium as a combined predictor of atrial fibrillation after elective coronary artery bypass surgery. | 1997 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Zaman AG Alamgir F Richens T |
| Millar N.S. | The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. | 1997 | University College London | Receptors, ion channels and transduction | Lewis, T. M. Harkness, P. C. Sivilotti, L. G. |
| Millar N.S. | Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor alpha 7 subunit. | 1997 | University College London | Receptors, ion channels and transduction | Cooper, S. T. |
| Michel A.D. | Radiolabeling of the rat P2X4 purinoceptor: evidence for allosteric interactions of purinoceptor antagonists and monovalent cations with P2X purinoceptors. | 1997 | University of Cambridge | Miller, K.J. Lundstrom, K. Buell, G.N. |
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| McNaughton P.A. | Actions of serum and plasma albumin on [Ca2+]i in human endothelial cells. | 1997 | University of Cambridge | Fuentes, E. Nadal, A. Jacob, R. |
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| Martin SJ | (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo | 1997 | University of Edinburgh | Neural Plasticity | Martin SJ Morris RGM |
| Marrion NV | Control of M-current. | 1997 | University of Bristol | ||
| Larkman PM | Modulation of IH by 5-HT in neonatal rat motoneurones In Vitro: Mediation through a phosphorylation independent action of cAMP | 1997 | University of Edinburgh | Neuropharmacology | Larkman PM Kelly JS |
| Kozlowski RZ | Electrophysiological consequences of purinergicreceptor stimulation in isolated rat pulmonary arterial myocytes. | 1997 | University of Bristol | Hartley,SA | |
| Koenig J.A. | Somatostatin receptors in Neuro2A neuroblastoma cells: operational characteristics. | 1997 | University of Cambridge | Edwardson, J.M. Humphrey, P.P.A. |
|
| Koenig J.A. | Somatostatin receptors in Neuro2A neuroblastoma cells: ligand internalization. | 1997 | University of Cambridge | Edwardson, J.M. Humphrey, P.P.A. |
|
| Kitteringham NR | The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat | 1997 | University of Liverpool | Drug Safety | Gill HJ Hough SJ Naisbitt DJ |
| Kidd B L | Characterisation of capsaicin-induced mechanical hyperalgesia as a marker for altered nociceptive processing in patients with rheumatoid arthritis. | 1997 | Queen Mary, University of London | Bone and Joint Research Unit | Cruwys SC Morris VH |
| Khoo SH | The integrin-triggered rescue of T lymphocyte apoptosis is blocked in HIV-1 infected individuals | 1997 | University of Liverpool | Pharmacology of HIV Disease | Ng TTC Kanner SB Humphries MJ |
| Khoo SH | Tumour Necrosis Factor c2 microsatellite allele is associated with the rate of HIV disease progression | 1997 | University of Liverpool | Pharmacology of HIV Disease | Ollier WER Hajeer A Snowden N |
| Kelly PAT | Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats | 1997 | University of Edinburgh | Neuropharmacology | Fouyas IP Kelly PAT Ritchie IM |
| Kelly EP | A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization | 1997 | University of Bristol | Mundell,SJ Benovic,JL |
|
| Kabouridis P | S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. | 1997 | Queen Mary, University of London | Bone and Joint Research Unit | Magee AI Ley SC |
| Jacobs M. | Modulation of vascular tone by low density lipoproteins: effects on L-arginine transport and nitric oxide synthesis. | 1997 | University College London | Receptors, ion channels and transduction | Jay, M.T. Chirico, S. Siow, R.C.M. |
| Humphrey P.P.A. | Somatostatin5 receptor-mediated [35S]Guanosine-5'-0-(3-thio)triphosphate binding: agonist potencies and the influence of sodium chloride on intrinsic activity. | 1997 | University of Cambridge | Williams, A .J. Michel, A.D. Feniuk, W. |
|
| Humphrey P.P.A. | Acute nociception mediated by hindpaw P2X receptor activation in the rat. | 1997 | University of Cambridge | Bland-Ward, P.A. | |
| Hiley C.R. | A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. | 1997 | University of Cambridge | White, R. | |
| Hiley C.R. | Endothelium and cannabinoid receptor involvement in levcromakalim vasorelaxation. | 1997 | University of Cambridge | White, R. | |
| Henderson R.M. | Structural activity of a cloned potassium channel (ROMK1) monitored with the atomic force microscope: the molecular-sandwich technique. | 1997 | University of Cambridge | Oberleithner, H. Schneider, S.W. |
|
| Henderson G | ATP-gated cation channels (P2x purinoceptors) in trigeminal mesencephalic nucleus neurones of the rat | 1997 | University of Bristol | Khakh,BS Humphrey,PPA |
|
| Grootveld M | Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: the roles of endogenous pyruvate and lactate. Relevance to inflammatory joint diseases. | 1997 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Herz H Blake DR |
| Grant SGN | A role for the Ras signalling pathway in synaptic transmission and long-term memory | 1997 | University of Edinburgh | Neural Plasticity | Brambilla R Gnesutta N Minichiello L |
| Goyal M | Differentiation of Mycobacterium tuberculosis Isolates by Spoligotyping and IS6110 Restriction Fragment Length Polymorphism | 1997 | University of Hertfordshire | Saunders NA van Embden JDA Young DB |
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| Gibb A.J. | Properties of ATP receptor-mediated synaptic transmission in the rat medial habenula. | 1997 | University College London | Neuropharmacology and neuroscience | Edwards, F. A. Robertson, S. J. |
| Getting S J | Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Flower RJ Parente L De Medicis R |
| Getting S J | Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Flower RJ Perretti M |
| Gergely F.V. | The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila. | 1997 | University of Cambridge | Micklem, D.R. Dasgupta, R. Elliott, H. |
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| Genazzani A.A. | Kinetic properties of Nicotinic Acid Adenine Dinucleotide Phosphate--induced Ca2+release. | 1997 | University of Cambridge | Mezna, M. Summerhill, R.J. Galione, A. |
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| Garthwaite J. | Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway. | 1997 | University College London | Neuropharmacology and neuroscience | Batchelor, A. M. |
| GRUBB B.D. | Prostanoids synthesised by cyclooxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability | 1997 | University of Leicester | Willingale, H.L. Gardiner, N.J. McLymont, N. |
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| GREENFIELD SA | Heterogeneity of electrically evoked dopamine release and reuptake in substantia nigra, ventral tegmental area and striatum | 1997 | University of Oxford | Neuroscience | Cragg, S.J. Rice, M.E. |
| GREENFIELD SA | Differential autoreceptor control of somatodendritic and axon terminal dopamine release in substantia nigra, ventral tegmental area, and striatum | 1997 | University of Oxford | Neuroscience | Cragg, S.J. |
| GREENFIELD SA | Characteristics of electrically evoked somatodendritic dopamine release in substantia nigra and ventral tegmental area in vitro | 1997 | University of Oxford | Neuroscience | Rice, M.E. Cragg, S.J. |
| GALIONE A | 7-deaza-8-bromo cyclic adenosine 5'-diphosphate ribose, the first membrane-permeant, hydrolysis-resistant cyclic ADP-ribose antagonist | 1997 | University of Oxford | Integrative Biology | Sethi, J.K. Empson, R. Bailey, V.C. |
| Forte P | Basal nitric oxide synthesis in essential hypertension [see comments] | 1997 | Queen Mary, University of London | Clinical Pharmacology | Copland M Smith LM Milne E |
| Flower R J | Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Szabo C Lim LH Cuzzocrea S |
| Flower R J | Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Cuzzocrea S Tailor A Zingarelli B |
| Fitzgerald E.M. | Regulation of rat neuronal voltage-dependent calcium channels by endogenous p21-ras. | 1997 | University College London | Neuropharmacology and neuroscience | Dolphin, A. C. |
| Finlayson K | Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists | 1997 | University of Edinburgh | Neuropharmacology | Maemoto T Finlayson K Olverman HJ |
| Finlayson K | Detection of adenosine receptor antagonists in rat brain using a modified radioreceptor assay | 1997 | University of Edinburgh | Neuropharmacology | Finlayson K Butcher SP Sharkey J |
| Ferguson D.R. | ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - a possible sensory mechanism? | 1997 | University of Cambridge | Kennedy, I. Burton, T.J. |
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| Feniuk W. | Characterization of human recombinant somatostatin sst5 receptors mediating activation of phosphoinositide metabolism. | 1997 | University of Cambridge | Wilkinson, G.F. Humphrey, P.P.A. |
|
| Fan T.P.D. | Sequential development of angiotensin receptors and angiotensin converting enzyme during angiogenesis in the rat subcutaneous sponge granuloma. | 1997 | University of Cambridge | Walsh, D.A. Hu, D.-E. Wharton, J. |
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| Edwardson J.M. | The secretory granule protein syncollin binds to syntaxin in a Ca2+-sensitive manner. | 1997 | University of Cambridge | An, S. Jahn, R. |
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| Edwards IG | The biliary metabolites of b-artemether, an endoperoxide antimalarial | 1997 | University of Liverpool | Tropical Pharmacology | Maggs JL Bishop LPD O'Neill PM |
| Dunn SMJ | Agonist binding to the Torpedo acetylcholine receptor (II) Complexities revealed by association kinetics. | 1997 | University of Bristol | Raftery,MA | |
| Dunn SMJ | Agonist binding to the Torpedo acetylcholine receptor (I) Complexities revealed by dissociation kinetics. | 1997 | University of Bristol | Raftery,MA | |
| Donaldson IML | Changes in dorsal neck muscle activity related to imposed eye movement in the decerebrate pigeon | 1997 | University of Edinburgh | Neural Plasticity | Hayman MR Donaldson IML |
| DAVIES N.W. | Kinetic analysis of the inhibitory effect of glibenclamide on KATP channels of mammalian skeletal muscle | 1997 | University of Leicester | Barrett-Jolley, R. | |
| Cull-Candy S.G. | Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition. | 1997 | University College London | Neuropharmacology and neuroscience | Swanson, G. T. Kamboj, S. K. |
| Cull-Candy S.G. | Differences in synaptic GABAA receptor number underlie variation in GABA mini amplitude. | 1997 | University College London | Neuropharmacology and neuroscience | Nusser, Z. Farrant, M. |
| Croxtall J D | Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A549 cells. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Choudhury Q White JO Flower RJ |
| Colville-Nash P R | The depletion of substance P by diclofenac in the mouse. | 1997 | Queen Mary, University of London | Biochemical Pharmacology | Papworth J Alam C Seed M |
| Colquhoun D. | Properties of single ion channel currents elicited by a pulse of agonist concentration or voltage. | 1997 | University College London | Receptors, ion channels and transduction | Hawkes, A.G. Merlushkin, A. Edmonds, B. |
| Coleman JW | Tumour necrosis factor-a expression and cell recruitment in Sephadex particle-induced lung inflammation: effects of dexamethasone and cyclosporin A | 1997 | University of Liverpool | Drug Safety | Williams CMM Smith L Flanagan BF |
| Coleman JW | Nitric oxide inhibits IgE-mediated degranulation of mast cellsand is the principal intermediate in IFN-g-induced suppression of exocytosis | 1997 | University of Liverpool | Drug Safety | Eastmond NC Banks EMS |
| Coker SJ | Comparison of the acute cardiotoxicity of the antimalarial drug halofantrine in vitro and in vivo in anaesthetized guinea pigs | 1997 | University of Liverpool | Tropical Pharmacology | Batey AJ Lightbown ID Lambert JP |
| Caulfield M J | Essential hypertension in African Caribbeans associates with a variant of the beta2-adrenoceptor. | 1997 | Queen Mary, University of London | Clinical Pharmacology | Kotanko P Binder A Tasker J |
| Carter T.D. | Kinetics of Ca2+ release by InsP3 in pig single aortic endothelial cells: evidence for an inhibitory role of cytosolic Ca2+ in regulating hormonally evoked Ca2+ spikes. | 1997 | University College London | Receptors, ion channels and transduction | Ogden, D. |
| Carter T.D. | Potency and kinetics of nitric oxide-mediated vascular smooth muscle relaxation determined with flash photolysis of ruthenium nitrosyl chlorides. | 1997 | University College London | Receptors, ion channels and transduction | Bettache, N. Ogden, D.C. |
| Callingham B.A. | Amine oxidases in inflammation: fact or fiction? | 1997 | University of Cambridge | Skamarauskas, J.T. Brown, S. Rainsford, K.D. |
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| CAVIERES J.D. | K+ induces an acid-labile phosphoenzyme (or an occluded Pi form) in Na,K-ATPase | 1997 | University of Leicester | Buxbaum, E. Ward, D.G. Walton, T. J. H. |
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| CAPOGNA M | Ca2+ or Sr2+ partially rescues synaptic transmission in hippocampal cultures treated with botulinium toxin A and C, but not tetanus toxin | 1997 | University of Oxford | Neuroscience | McKinney, R.A. O'Connor, V. Gahwiler, B.H. |
| Breckenridge AM | Saquinavir kinetics alone and in combination with ritonavir in HIV infected patients | 1997 | University of Liverpool | Pharmacology of HIV Disease | Merry C Barry MG Mulcahy F |
| Born G V R | Effect of deoxycorticosterone acetate on blood pressure in relation to accumulation of low-density lipoprotein and fibrinogen by aorta and other tissues of normotensive Wistar rats. | 1997 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Medina RA Cardona-Sanclemente LE Brown MJ |
| Born G V R | Effect of captopril and losartan on blood pressure and accumulation of LDL and fibrinogen by aortic wall and other tissues in normotensive and hypertensive rats. | 1997 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Medina R Cardona-Sanclemente LE Brown MJ |
| Bishop-Bailey D | Induction of cyclooxygenase-2 in human saphenous vein and internal mammary artery. | 1997 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Pepper JR Haddad EB Newton R |
| Barrand M.A. | Changes in anion permeability following hypotonic challenge in rat brain endothelial cells: a comparison of responses in primary cultures and in immortalised RBE-4 cells. | 1997 | University of Cambridge | von Weikersthal, S.F. Seetharaman, S. Wright, K.A. |
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| Barnard E.A. | Xenopus oocytes express a unitary glutamate receptor endogenously. | 1997 | University of Cambridge | Soloviev, M.M. | |
| BRADING AF | Smooth muscle of the bladder in the normal and the diseased state: pathophysiology, diagnosis and treatment | 1997 | University of Oxford | Integrative Biology | Turner, W.H. |
| BLANK J.L. | Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase1 and MKK3/p38 pathways regulated by MEK Kinase 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo | 1997 | University of Leicester | Deacon, K. | |
| Arbuthnott GW | Plasticity of striatopallidal terminals following unilateral lesion of the dopaminergic nigrostriatal pathway: A morphological study | 1997 | University of Edinburgh | Neural Plasticity | Ingham CA Hood SH Mijnster MJ |
| van Veen H.W. | Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane. | 1996 | University of Cambridge | Bolhuis, H. Molenaar, D. Poolman, B. |
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| van Veen H.W. | Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1. | 1996 | University of Cambridge | Venema, K. Bolhuis, B. Oussenko, I. |
|
| Yaqoob M T | Modulation of hypoxia-induced calpain activity in rat proximal tubules. | 1996 | Queen Mary, University of London | Experimental Medicine and Nephrology | Edelstein CL Alkhunaizi AM Gengaro PE |
| Yaqoob M T | Arachidonic acid protects against hypoxic injury in rat proximal tubules. | 1996 | Queen Mary, University of London | Experimental Medicine and Nephrology | Alkhunaizi AM Edelstein CL Gengaro PE |
| Winyard P G | Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite. | 1996 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Frears ER Zhang Z Blake DR |
| Winyard P G | Activation of the transcription factor nuclear factor-kappaB in human inflamed synovial tissue. | 1996 | Queen Mary, University of London | Pharmaceutical Bioanalysis | Marok R Coumbe A Kus ML |
| Willoughby D A | Heme oxygenase: a novel target for the modulation of the inflammatory response. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Willis D Moore AR Frederick R |
| Willis D. | Heme oxygenase: a novel target for the modulation of the inflammatory response. | 1996 | University College London | Receptors, ion channels and transduction | Moore, A.R. Frederick, R. Willoughby, D.A. |
| Ward SA | 4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake | 1996 | University of Liverpool | Tropical Pharmacology | Bray PG Hawley SR |
| Ward SA | Physicochemical properties correlated with drug resistance and its reversal in Plasmodium falciparum | 1996 | University of Liverpool | Tropical Pharmacology | Bray PG Hawley SR |
| Walley TJ | Influences of practice characteristics on prescribing in fundholding and non-fundholding general practices | 1996 | University of Liverpool | Prescribing Research Group | Wilson R Hatcher J Barton S |
| Vane J | Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat. | 1996 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Thiemermann C Ruetten H |
| Usowicz MM | Ca2+ entry following store depletion in SH-SY5Y neuroblastoma cells | 1996 | University of Bristol | Grudt,TJ Henderson,G |
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| Usowicz MM | Differential inhibition of Ca2+ channels in mature rat cerebellar Purkinje cells by sFTX-3.3 and FTX-3.3 | 1996 | University of Bristol | Dupere,JRB Moya,E Blagbrough,IS |
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| Timmis A D | Comparison of case fatality in south Asian and white patients after acute myocardial infarction: observational study [see comments] | 1996 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Wilkinson P Sayer J Laji K |
| Thorn P. | Multiple, coordinated Ca2+-release events underlie the inositol trisphosphate-induced local Ca2+ spikes in mouse pancreatic acinar cells. | 1996 | University of Cambridge | Moreton, R. Berridge, M. |
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| Thomas P. | The LbT2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion. | 1996 | University of Cambridge | Mellon, P.L. Turgeon, J.L. Waring, D.W. |
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| TERRAR DA | A specific cyclic ADP-ribose antagonist inhibits cardiac excitation-contraction coupling | 1996 | University of Oxford | Integrative Biology | Rakovic, S. Galione, A. Ashamu, G.A. |
| Stanford S.C. | Prozac: panacea or puzzle? | 1996 | University College London | Neuropharmacology and neuroscience | |
| Skehel PA | A tri-hybrid system for the analysis and detection of RNA-protein interactions | 1996 | University of Edinburgh | Neural Plasticity | Putz U Skehel P Kuhl D |
| Schoepfer R. | Mutiple structural elements determine subunit-specificity of Mg2+ block in NMDA receptor channels. | 1996 | University College London | Receptors, ion channels and transduction | Kuner, T. |
| SOMOGYI P | Target-cell specific concentration of a metabotropic glutamate receptor in the presynaptic active zone | 1996 | University of Oxford | Neuroscience | Shigemoto, R. Kulik, A. Roberts, J.D. |
| SMITH AD | Use of structural imaging to study the progression of Alzheimer's disease | 1996 | University of Oxford | Neuroscience | Jobst, K.A. |
| Roberts PJ | Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures | 1996 | University of Bristol | Bruno,V Copani,A Bonanno,L |
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| Roberts PJ | The effects of (RS)-a-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist | 1996 | University of Bristol | Toms,NJ Jane,DE Kemp,MC |
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| Ramage A.G. | Involvement of central 5-HT1A receptors in the reflex activation of pulmonary vagal motoneurones by inhaled capsaicin in anaesthetized cats. | 1996 | University College London | Neuropharmacology and neuroscience | Bootle, D. J. Adcock, J. J. |
| ROEPER J | Kv beta 1 subunit binding specific for Shaker-related potassium channel alpha subunits | 1996 | University of Oxford | Neuroscience | Sewing, S. Pongs, O. |
| Pitcher J.A. | Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies. | 1996 | University College London | Receptors, ion channels and transduction | Fredericks, Z. L. Stone, W. C. Premont, R. T. |
| Pirmohamed M | Intracellular glutathione in the peripheral blood cells of HIV-infected patients: failure to show a deficiency | 1996 | University of Liverpool | Drug Safety | Williams DP Wilkins EGL Park BK |
| Perretti M | Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Croxtall JD Wheller SK Goulding NJ |
| Perretti M | Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Ahluwalia A |
| Nissim A | Screening of phage antibody libraries. | 1996 | Queen Mary, University of London | Bone and Joint Research Unit | Harrison JL Williams SC Winter G |
| NAHORSKI S.R. | Identification of a novel receptor kinase that phosphorylates a phospholipase C-linked muscarinic receptor | 1996 | University of Leicester | Tobin A.B. Keys B. |
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| Munroe P B | Prenatal diagnosis of Batten's disease. | 1996 | Queen Mary, University of London | Clinical Pharmacology | Rapola J Mitchison HM Mustonen A |
| Moss S.J. | Subcellular localisation of gamma-aminobutyric acid type A receptors is determined by receptor beta subunits. | 1996 | University College London | Receptors, ion channels and transduction | Connolly, C. N. Wooltorton, J. A. Smart, T. G. |
| Moss G.W.J. | Hypothesis for a serine proteinase-like domain at the COOH terminus of slowpoke calcium-activated potassium channels. | 1996 | University College London | Receptors, ion channels and transduction | Marshall, J. Moczydlowski |
| Moss G.W.J. | An evolutionarily conserved binding site for serine proteinase inhibitors in large conductance calcium-activated potassium channels. | 1996 | University College London | Receptors, ion channels and transduction | Marshall, J. Morabito, M. Howe, J.R. |
| Moss G.W.J. | Rectifying conductance substates in a large conductance Ca(2+)-activated K+ channel: evidence for a fluctuating barrier mechanism. | 1996 | University College London | Receptors, ion channels and transduction | Moczydlowski, E. |
| Mills P G | Extent of oxidative modification of low density lipoprotein determines the degree of cytotoxicity to human coronary artery cells. | 1996 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Thorne SA Abbot SE Winyard PG |
| Mills P G | Modified low density lipoprotein and cytokines mediate monocyte adhesion to smooth muscle cells. | 1996 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Thorne SA Abbot SE Stevens CR |
| McQueen DS | Secretoneurin: a novel carotid body peptide | 1996 | University of Edinburgh | Neuropharmacology | McQueen DS Winkler H Eder U |
| McNaughton P.A. | A novel heat-activated current in nociceptive neurones and its sensitization by bradykinin. | 1996 | University of Cambridge | Cesare, P. | |
| Matthews E.K. | Cytotoxic, nuclear, and growth inhibitory effects of photodynamic drugs on pancreatic carcinoma cells. | 1996 | University of Cambridge | Ward, A.J. | |
| Matthews E.K. | Dynamics of actin measured by fluorescence correlation microscopy (FCM). | 1996 | University of Cambridge | Terry, B.R. | |
| Marston H | Tacrolimus (FK506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats | 1996 | University of Edinburgh | Neuropharmacology | Sharkey J Crawford JH Butcher SP |
| Marshall I. | The role of diacylglycerol and activation of protein kinase C in the alpha 1A-adrenoceptor-mediated contraction to noradrenaline of the rat isolated epididymal vas deferens. | 1996 | University College London | Receptors, ion channels and transduction | Burt, R. P. Chapple, C. R. |
| Marshall I. | Different subtypes of alpha1A-adrenoceptor mediating contraction of rat epididymal vas deferens, rat hepatic portal vein and human prostate distinguished by the antagonist RS 17053 | 1996 | University College London | Receptors, ion channels and transduction | Burt, R. P. Green, G. M. Hussain, M. B. |
| Marrion NV | Calcineurin regulates M-channel modal gating in sympathetic neurons. | 1996 | University of Bristol | ||
| MCILHINNEY RAJ | Myristoylation does not modulate the properties of MARCKS-related protein (MRP) in solution | 1996 | University of Oxford | Neuroscience | Schleiff, E. Schmitz, A. Manenti, S. |
| MCILHINNEY RAJ | Cell surface expression of the human N-methyl-D-aspartate receptor subunit 1a requires the co-expression of the NR2A subunit in transfected cells | 1996 | University of Oxford | Neuroscience | Molnar, E. Atack,J.R. Whiting, P.J. |
| La M | Comparison of the effects of hydroxocobalamin and oxyhaemoglobin on responses to NO, EDRF and the nitrergic transmitter. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Li CG Rand MJ |
| Kitteringham NR | Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene | 1996 | University of Liverpool | Drug Safety | Davis C Howard N Pirmohamed M |
| Kidd B L | Effect of streptozotocin-diabetes on knee joint inflammation-induced changes in substance P and nerve growth factor in the rat. | 1996 | Queen Mary, University of London | Bone and Joint Research Unit | Garrett NE Cruwys SC Tomlinson DR |
| Kidd B L | A multicenter, randomized, double blind study comparing lornoxicam with diclofenac in osteoarthritis. | 1996 | Queen Mary, University of London | Bone and Joint Research Unit | Frenzel W |
| Kelly PAT | Cerebrovascular responsiveness to NG-nitro-L-arginine methyl ester in spontaneously diabetic rats | 1996 | University of Edinburgh | Neuropharmacology | Fouyas IP Kelly PAT Ritchie IM |
| Kelly JS | Glucocorticoids block protein kinase A inhibition of calcium-activated potassium channels | 1996 | University of Edinburgh | Neuropharmacology | Shipston MJ Kelly JS Antoni FA |
| Jenkinson D.H. | Discrimination between subtypes of apamin-sensitive Ca | 1996 | University College London | Receptors, ion channels and transduction | Dunn, P. M. Benton, D. C. H. Campos Rosa, J. |
| Jacobs M. | Oxidized low-density lipoproteins inhibit endothelium-dependent relaxations in isolated large and small rabbit coronary arteries. | 1996 | University College London | Receptors, ion channels and transduction | Buckley, C. Bund, S.J. McTaggart, F. |
| Ismail FMD | An exploration of the structure-activity relationships of 4-aminoquinolones: Novel antimalarials with activity in vivo | 1996 | University of Hertfordshire | Dascombe MJ Carr P North SE |
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| Ismail FMD | An inhibitor of the sodium pump obtained from human placenta | 1996 | University of Hertfordshire | Hilton PJ White RW Lord GA |
|
| Irvine R.F. | Aggregation-dependent, integrin-mediated increases in cytoskeletally associated PtdInsP2(4,5) levels in human platelets are controlled by translocation of PtdIns 4-P 5-kinase C to the cytoskeleton. | 1996 | University of Cambridge | Hinchliffe, K.A., Divecha, N. |
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| Hoffman R | Inhibition of Angiogenesis and murine tumour growth by laminarin sulphate | 1996 | University of Hertfordshire | Paper DH Donaldson J Vogl H |
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| Hladky S.B. | Hypotonicity-induced anion fluxes in cells expressing the multidrug resistance associated protein, MRP. | 1996 | University of Cambridge | Hainsworth, A.H. Henderson, R.M. Hickman, M.E. |
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| Henderson R.M. | Imaging ROMK1 inwardly rectifying ATP-sensitive K+ channel protein using atomic force microscopy. | 1996 | University of Cambridge | Schneider, S. Li, Q. Hornby, D. |
|
| Hemming K | The preparation of 4-substituted pyrilium salts and their use in dienal synthesis | 1996 | University of Hertfordshire | Charoenying P McKerrecher D Taylor RJK |
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| Harmar AJ | Polymorphism in serotonin transporter gene associated with susceptibility to major depression | 1996 | University of Edinburgh | Neuropharmacology | Ogilvie AD Battersby S Bubb VJ |
| Goulding N J | Evidence for specific annexin I-binding proteins on human monocytes. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Pan L Wardwell K Guyre VG |
| Gibb A.J. | Receptors linked to ion channels: activation and block. | 1996 | University College London | Neuropharmacology and neuroscience | |
| Gibb A.J. | Fast purinergic synaptic transmission in the central nervous system. | 1996 | University College London | Neuropharmacology and neuroscience | Halliday, F. C. |
| Genazzani A.A. | Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive pool | 1996 | University of Cambridge | Galione, A | |
| Genazzani A.A. | Unique inactivation properties of NAADP-sensitive Ca2+ release | 1996 | University of Cambridge | Empson, R.M. Galione, A. |
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| Garthwaite J. | Tyrosine kinase is required for long term depression in the cerebellum. | 1996 | University College London | Neuropharmacology and neuroscience | Boxall, A. Lancaster, B. |
| Garthwaite J. | Vicious cycle involving Na+ channels, glutamate release and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation. | 1996 | University College London | Neuropharmacology and neuroscience | Strijbos, P. J. L. M. Leach, M. J. |
| GALIONE A | Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway | 1996 | University of Oxford | Integrative Biology | Willmott, N.J. Sethi, J.K. Walseth, T.F. |
| GABBOTT PLA | Calretinin neurons in human medial prefrontal cortex (areas 24a,b,c, 32' and 25) | 1996 | University of Oxford | Neuroscience | Jays, P.R. Bacon, S.J. |
| Foreman J.C. | Inhibitors of nitric oxide synthase in human skin. | 1996 | University College London | Receptors, ion channels and transduction | Goldsmith, P. C. Leslie, T. A. Hayes, N. A. |
| Ford W.R. | Opposite effects of angiotensin AT1 and AT2 receptor antagonists on recovery of mechanical function after ischemia-reperfusion in isolated working rat hearts. | 1996 | University of Cambridge | Clanachan, A.S. Jugdutt, B.I. |
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| Flower R J | Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Perretti M Ahluwalia A Harris JG |
| Fitzgerald E.M. | Maintenance of the K+ activity gradient in insect muscle compared in Diptera and Lepidoptera: Contributions of metabolic and exchanger mechanisms. | 1996 | University College London | Neuropharmacology and neuroscience | Djamgoz, M. B. A. Dunbar, S. J. |
| Fan T.P.D. | Differential effects of angiostatic steroids and dexamethasone on angiogenesis and cytokine levels in rat sponge implants. | 1996 | University of Cambridge | Hori, Y. Hu, D.-E. Yasui, K. |
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| FORSYTHE I.D. | Presynaptic calcium current modulation by a metabotropic glutamate receptor | 1996 | University of Leicester | Takahashi, T. Tsujimoto T. Barnes-Davies M |
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| EMPTAGE NJ | Pharmacological and kinetic characterization of two functional classes of serotonergic modulation in Aplysia sensory neurons | 1996 | University of Oxford | Neuroscience | Stark, L.L. Mercer, A.R. Carew, T.J. |
| EMPTAGE NJ | Threshold serotonin concentration required to produce synaptic facilitation differs for depressed and nondepressed synapses in Aplysia sensory neurons | 1996 | University of Oxford | Neuroscience | Mauelshagen, J. Carew, T.J. |
| DAVIES N.W. | A rate theory model for Mg2+ block of ATP-dependent potassium channels of rat skeletal muscle | 1996 | University of Leicester | McKillen, H.-C. Stanfield, P.R. Standen, N.B. |
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| DART C. | The properties and distribution of inward rectifier potassium currents in pig coronary arterial smooth muscle | 1996 | University of Leicester | Quayle, J.M. Standen N.B. |
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| Croxtall J D | The concerted regulation of cPLA2, COX2, and lipocortin 1 expression by IL-1beta in A549 cells. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Newman SP Choudhury Q Flower RJ |
| Corder R | The conformation of human big endothelin-1 favours endopeptidase hydrolysis of the TRP21-VAL22 bond. | 1996 | Queen Mary, University of London | Experimental Therapeutics | |
| Colville-Nash P R | The role of vascular endothelial growth factor in a murine chronic granulomatous tissue air pouch model of angiogenesis. | 1996 | Queen Mary, University of London | Biochemical Pharmacology | Appleton I Brown NJ Willis D |
| Caulfield M J | Angiotensinogen in human essential hypertension. | 1996 | Queen Mary, University of London | Clinical Pharmacology | Lavender P Newell-Price J Kamdar S |
| Carter T.D. | Porcine aortic endothelial gap junctions: identification and permeation by caged InsP3. | 1996 | University College London | Receptors, ion channels and transduction | Chen, X.Y Carlile, G. Kalapothakis, E. |
| CHALLISS R.A.J. | Stable overexpression of the type-1 inositol 1,4,5-trisphosphate receptor in L fibroblasts: subcellular distribution and functional consequences | 1996 | University of Leicester | Mackrill J.J. Wilcox R.A. Miyawaki A., |
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| CAVIERES J.D. | Binding of 2'(3')-O-(2,4,6- trinitrophenyl)ADP to soluble alphabeta protomers of Na,K-ATPase modified with fluorescein isothiocyanate - Evidence for two distinct nucleotide sites | 1996 | University of Leicester | Ward D.G. | |
| CAPOGNA M | Organotypic slice cultures: a technique has come of age | 1996 | University of Oxford | Neuroscience | Gahwiler, B.H. Debanne, D. McKinney, R.A. |
| CAPOGNA M | Calcium-independent actions of alpha-latrotoxin on spontaneous and evoked synaptic transmission in the hippocampus | 1996 | University of Oxford | Neuroscience | Gahwiler, B.H. Thompson, S.M. |
| Brown D.A. | Detection and modulation of acetylcholine release from neurites of rat cultured basal forebrain cells | 1996 | University College London | Neuropharmacology and neuroscience | Allen, T.G.J. |
| Breckenridge AM | Delta Steering Committee (A. Breckenridge, Chairman). Delta | 1996 | University of Liverpool | Pharmacology of HIV Disease | Aber V Aboulker J-P Babiker AG |
| Born G V R | Increase by adrenaline or angiotensin II of the accumulation of low density lipoprotein and fibrinogen by aortic walls in unrestrained conscious rats. | 1996 | Queen Mary, University of London | Cardiac, Vascular and Inflammation Research | Cardona-Sanclemente LE |
| Benjamin N | Plasma nitrate concentration in infective gastroenteritis and inflammatory bowel disease. | 1996 | Queen Mary, University of London | Clinical Pharmacology | Dykhuizen RS Masson J McKnight G |
| Benjamin N | Antimicrobial effect of acidified nitrite on gut pathogens: importance of dietary nitrate in host defense. | 1996 | Queen Mary, University of London | Clinical Pharmacology | Dykhuizen PS Frazer R Duncan C |
| Barrand M.A. | Hypotonicity-induced changes in anion permeability of cultured rat brain endothelial cells. | 1996 | University of Cambridge | von Weikersthal, S.F. Hickman, M.E. Hladky, S.B. |
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| Barnard E.A. | The P2Y purinoceptor in rat brain microvascular endothelial cells couples to inhibition of adenylate cyclase. | 1996 | University of Cambridge | Webb, T.E. Feolde, F. Vigne, P. |
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| BLANK J.L. | Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase | 1996 | University of Leicester | Gerwins, P. Elliott, E.M. Sather, S. |
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| Arbuthnott GW | Dopamine reverses the depression of rat cortico-striatal synapses which normally follows high frequency stimulation of cortex in vitro | 1996 | University of Edinburgh | Neural Plasticity | Wickens JR Begg AJ Arbuthnott GW |
| Annenkov A E | The beta 2 integrin Mac-1 but not p150,95 associates with Fc gamma RIIA. | 1996 | Queen Mary, University of London | Bone and Joint Research Unit | Ortlepp S Hogg N |
| Anggard E | Investigation of endogenous nitric oxide vascular function in the carotid artery of cholesterol-fed rabbits. | 1996 | Queen Mary, University of London | Experimental Therapeutics | Laight D Matz J Caesar B |
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