Pharmacology - Publications
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Author Title Date Place of Publication Research Group Co-Authors
Martin SJ (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo 1997 University of Edinburgh Neural Plasticity Martin SJ
Morris RGM
NICOTERA PL 1-methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation and neuronal apoptosis 1998 University of Leicester   Leist, M.
Volbracht, C.
Fava, E.
EVANS R.J. 2',3'-0-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP) a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels 1998 University of Leicester   Lewis C.J.
Surprenant A.
Jacobs M. 3-Nitrotyrosine in the proteins of human plasma determined by an ELISA method. 1998 University College London Receptors, ion channels and transduction Khan, J.
Brennan, D.M.
Bradley, N.
Ward SA 4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake 1996 University of Liverpool Tropical Pharmacology Bray PG
Hawley SR
Kelly PAT 7-Nitroindazole reduces cerebral blood flow following chronic nitric oxide synthase inhibition 2000 University of Edinburgh Neuropharmacology Kelly PAT
Ritchie IM
McBean DE
GALIONE A 7-deaza-8-bromo cyclic adenosine 5'-diphosphate ribose, the first membrane-permeant, hydrolysis-resistant cyclic ADP-ribose antagonist 1997 University of Oxford Integrative Biology Sethi, J.K.
Empson, R.
Bailey, V.C.
van Veen H.W. A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. 1998 University of Cambridge   Callaghan, R.
Soceneantu, L.
Sardini, A.
Thorn P. A bimodal pattern of InsP3-evoked elementary Ca2+ signals in pancreatic acinar cells. 2000 University of Cambridge   Fogarty, K.E.
Kidd, J.F.
Tuft, R.A.
Henderson R.M. A cell-free system for regulated exocytosis on PC12 cells. 2000 University of Cambridge   Avery, J.
Ellis, D.J.
Lang, T.
Hemming K A clean and efficient synthesis of 5-(2'-fluoro-2',3'-dimethylbutanyl-3'-yl) substituted 1,2,4-oxadiazoles using silver tetrafluoroborate as a fluorodesulfurization reagent 2000 University of Hertfordshire   Morgan DT
Smalley RK
Hiley C.R. A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. 1997 University of Cambridge   White, R.
Whelan CJ A comparison of the inhibitory effects of budesonide, beclomethasone dipropionate, dexamethasone, hydrocortisone and tixocortol pivalate on cytokine release from leukocytes recovered from human bronchoalveolar lavage fluid 1999 University of Hertfordshire   Payne A
Planquois J M
Kelly EP A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization 1997 University of Bristol   Mundell,SJ
Benovic,JL
Matthews E.K. A key role for the mitochondrial benzodiazepine receptor in cellular photosensitisation with d-aminolaevulinic acid. 2000 University of Cambridge   Mesenholler, M.
Martin SJ A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease 2000 University of Edinburgh Neural Plasticity Chen G
Chen KS
Knox J
Morris RGM A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimers disease 2000 University of Edinburgh Neural Plasticity Chen G
Chen KS
Knox J
Stanford S.C. A microdialysis study of the noradrenergic response in rat frontal cortex and hypothalamus to a conditioned cue for aversive, naturalistic environmental stimuli. 2000 University College London Neuropharmacology and neuroscience McQuade, R.
PAULSEN OKH A model of hippocampal memory encoding and retrieval: GABAergic control of synaptic plasticity 1998 University of Oxford Neuroscience Moser, E.I.
Sihra T.S. A modulatory role for protein phosphatase 2B (calcineurin) in the regulation of Ca 2000 University College London Neuropharmacology and neuroscience Burley, J. R.
Kidd B L A multicenter, randomized, double blind study comparing lornoxicam with diclofenac in osteoarthritis. 1996 Queen Mary, University of London Bone and Joint Research Unit Frenzel W
Kozlowski RZ A novel anionic conductance affects action potential duration in isolated rat ventricular myocytes. 2000 University of Bristol   Spencer,CI
Uchida,W
Gould D J A novel doxycycline inducible autoregulatory plasmid which displays 'on'/'off' regulation suited to gene therapy applications. 2000 Queen Mary, University of London Bone and Joint Research Unit Berenstein M
Dreja H
Ledda F
McNaughton P.A. A novel heat-activated current in nociceptive neurones and its sensitization by bradykinin. 1996 University of Cambridge   Cesare, P.
Marrion NV A novel lipid-anchored A-kinase anchoring protein facilitates cAMP-responsive membrane events 1998 University of Bristol   Fraser,IDC
Tavalin,SJ
Lester,LB
Hemming K A one-pot Aza-Wittig based solution and polymer supported route to amines 2000 University of Hertfordshire   Bevan MJ
Loukou C
Patel SD
Chan W L A proinflammatory role for IL-18 in rheumatoid arthritis [see comments] 1999 Queen Mary, University of London Bone and Joint Research Unit Gracie JA
Forsey RJ
Gilmour A
Sharkey J A rat model of Endothelin-3-induced middle cerebral artery occlusion with controlled reperfusion 1999 University of Edinburgh Neuropharmacology Henshall DC
Butcher SP
Sharkey J
DAVIES N.W. A rate theory model for Mg2+ block of ATP-dependent potassium channels of rat skeletal muscle 1996 University of Leicester   McKillen, H.-C.
Stanfield, P.R.
Standen, N.B.
DAVIES N.W. A residue in the intracellular vestibule of the pore is critical for gating and permeation in Ca2+-activated K+ (BKca) channels 2000 University of Leicester   Lippiat, J.D.
Standen N.B.
Grant SGN A role for the Ras signalling pathway in synaptic transmission and long-term memory 1997 University of Edinburgh Neural Plasticity Brambilla R
Gnesutta N
Minichiello L
TERRAR DA A specific cyclic ADP-ribose antagonist inhibits cardiac excitation-contraction coupling 1996 University of Oxford Integrative Biology Rakovic, S.
Galione, A.
Ashamu, G.A.
MITCHESON J. A structural basis for drug-induced long QT syndrome 2000 University of Leicester   Chen J.
Lin M.
Culberson C.
Hemming K A thiazine-S-oxide, Staudinger/Aza-Wittig based synthesis of benzodiazepines and benzothiadiazeoines 2000 University of Hertfordshire   Anwar B
Grimsey P
Krajniewski M
Skehel PA A tri-hybrid system for the analysis and detection of RNA-protein interactions 1996 University of Edinburgh Neural Plasticity Putz U
Skehel P
Kuhl D
O'Byrne S ACE inhibition: postsynaptic adrenergic sympatholytic action in men [see comments] 1997 Queen Mary, University of London Clinical Pharmacology Lyons D
Roy S
Swift CG
EVANS AM ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor: a primary role for cADPR in hypoxic pulmonary vasoconstriction 2000 University of Oxford Integrative Biology Wilson, H. L.
Dipp, M.
Thomas, J.M.
NICOTERA PL ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation 1999 University of Leicester   Volbracht, C.
Leist M.
Ferguson D.R. ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - a possible sensory mechanism? 1997 University of Cambridge   Kennedy, I.
Burton, T.J.
Henderson G ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain 1998 University of Bristol   Khakh,BS
Henderson G ATP-gated cation channels (P2x purinoceptors) in trigeminal mesencephalic nucleus neurones of the rat 1997 University of Bristol   Khakh,BS
Humphrey,PPA
STANDEN N.B. ATP-sensitive K+ channel activation by calcitonin gene-related peptide and protein kinase A in pig coronary arterial smooth muscle 1998 University of Leicester   Wellman, G.C.
Quayle, J.M.
STANDEN N.B. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle 1997 University of Leicester   Quayle, J.M.
Nelson, M.T.
SMITH AD Abnormal function of potassium channels in platelets of patients with Alzheimer's disease 1998 University of Oxford Neuroscience de Silva, H.A.
Aronson, J.K.
Grahame-Smith, D.G.
Morton A.J. Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's Disease mutation 2000 University of Cambridge   Murphy, K.P.S.J.
Carter, R.J.
Lione. L.A.
Caulfield M J Absence of linkage of the epithelial sodium channel to hypertension in black Caribbeans. 1998 Queen Mary, University of London Clinical Pharmacology Munroe PB
Strautnieks SS
Farrall M
Ward SA Access to heamatin: the basis of chloroquine resistance 1998 University of Liverpool Tropical Pharmacology Bray PG
Mungthin M
Ridley RG
McNaughton P.A. Actions of serum and plasma albumin on [Ca2+]i in human endothelial cells. 1997 University of Cambridge   Fuentes, E.
Nadal, A.
Jacob, R.
Sellers L.A. Activated G protein-coupled receptor induces tyrosine phosphorylation of STAT3 and agonist-selective serine phosphorylation via sustained stimulation of mitogen-activated protein kinase. 1999 University of Cambridge   Feniuk, W.
Humphrey, P.P.A.
Lauder, H.
Winyard P G Activation of NF-kappaB in human osteoblasts by stimulators of bone resorption. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Ali NN
Gilston V
McQueen DS Activation of P2X receptors for adenosine triphosphate evokes cardiorespiratory reflexes in anaesthetized rats 1998 University of Edinburgh Neuropharmacology McQueen DS
Bond SM
Moores C
Humphrey P.P.A. Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO-K1 cells and involvement of Gas proteins. 1999 University of Cambridge   Carruthers, A.M.
Warner, A.J.
Michel, A.D.
Ferguson D.R. Activation of epithelial Na+ channel activity in the rabbit urinary bladder by cAMP. 2000 University of Cambridge   Burton, T.J.
Elneil, S.
Nelson, C.P.
Roberts PJ Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures 1996 University of Bristol   Bruno,V
Copani,A
Bonanno,L
BRUNSKILL N.J. Activation of mitogenic pathways by albumin in kidney proximal tubule epithelial cells: Implications for the pathophysiology of proteinuric states 1999 University of Leicester   Dixon R.J.
TOBIN A.B. Activation of the mitogen-activated protein kinase pathway by a Gq/11 coupled muscarinic receptor is independent of receptor internalisation 1999 University of Leicester   Budd D.C.
Rae A.
Winyard P G Activation of the transcription factor nuclear factor-kappaB in human inflamed synovial tissue. 1996 Queen Mary, University of London Pharmaceutical Bioanalysis Marok R
Coumbe A
Kus ML
WILLARS G.B. Acute desensitization of phospholipase C-coupled muscarinic M3 receptors but not gonadotropin-releasing hormone receptors co-expressed in alphaT3-1 cells: implications for mechanisms of rapid desensitization 1998 University of Leicester   McArdle, C.A.
Nahorski, S.R.
Flower R J Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1. 1996 Queen Mary, University of London Biochemical Pharmacology Perretti M
Ahluwalia A
Harris JG
Barakat K Acute myocardial infarction in women: contribution of treatment variables to adverse outcome [In Process Citation] 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Wilkinson P
Suliman A
Ranjadayalan
Humphrey P.P.A. Acute nociception mediated by hindpaw P2X receptor activation in the rat. 1997 University of Cambridge   Bland-Ward, P.A.
Richardson P.J. Adenosine receptor expression and function in rat striatal cholinergic interneurones. 2000 University of Cambridge   Preston, Z.
Lee, K
Freeman, T.C.
Khoo SH Adenoviruses from human immunodeficiency virus-infected individuals, including two strains that represent new candidate serotypes Ad50 and Ad51 of subspecies B1 and D respectively 1999 University of Liverpool Pharmacology of HIV Disease De Jong JC
Hierholzer JC
van Doornum GJJ
Hladky S.B. Adjustments for the display of quantized ion channel dwell times in histograms with logarithmic bins. 2000 University of Cambridge   Stark, J.A.
Donaldson IML Afferent signals from the extraocular muscles affect the gain of the horizontal vestibulo-ocular reflex in the alert pigeon 2000 University of Edinburgh Neural Plasticity Donaldson IML
Knox PC
CAVIERES J.D. Affinity labeling of two nucleotide sites on Na,K-ATPase using 2 1998 University of Leicester   Ward D.G.
Irvine R.F. Aggregation-dependent, integrin-mediated increases in cytoskeletally associated PtdInsP2(4,5) levels in human platelets are controlled by translocation of PtdIns 4-P 5-kinase C to the cytoskeleton. 1996 University of Cambridge   Hinchliffe, K.A.,
Divecha, N.
Dunn SMJ Agonist binding to the Torpedo acetylcholine receptor (I) Complexities revealed by dissociation kinetics. 1997 University of Bristol   Raftery,MA
Dunn SMJ Agonist binding to the Torpedo acetylcholine receptor (II) Complexities revealed by association kinetics. 1997 University of Bristol   Raftery,MA
Marshall I. Alpha1A-adrenoceptor mediated contraction of rat prostatic vas deferens and the involvement of ryanodine stores and Ca 1998 University College London Receptors, ion channels and transduction Burt, R. P.
Chapple, C. R.
ROEPER J Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic in midbrain neurons 1999 University of Oxford Neuroscience Liss, B.
Bruns, A.
Kelly JS Alzheimer's disease: the tacrine legacy 1999 University of Edinburgh Neuropharmacology Kelly JS
Chernajovsky Y Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy. 1999 Queen Mary, University of London Bone and Joint Research Unit Triantaphyllopoulos KA
Williams RO
Tailor H
Callingham B.A. Amine oxidases in inflammation: fact or fiction? 1997 University of Cambridge   Skamarauskas, J.T.
Brown, S.
Rainsford, K.D.
TERRAR DA An antagonist of cADP-ribose inhibits arrhythmogenic oscillations of intracellular Ca2+ in heart cells 1999 University of Oxford Integrative Biology Rakovic, S.
Cui, Y.
Iino, S.
Stocker M. An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons. 1999 University College London Receptors, ion channels and transduction Krause, M.
Pedarzani, P.
Sihra T.S. An essential role for a small synaptic vesicle-associated phosphatidylinositol 4-kinase in neurotransmitter release. 1998 University College London Neuropharmacology and neuroscience Wiedemann, C.
Schafer, T.
Burger, M. M.
Moss G.W.J. An evolutionarily conserved binding site for serine proteinase inhibitors in large conductance calcium-activated potassium channels. 1996 University College London Receptors, ion channels and transduction Marshall, J.
Morabito, M.
Howe, J.R.
Ismail FMD An exploration of the structure-activity relationships of 4-aminoquinolones: Novel antimalarials with activity in vivo 1996 University of Hertfordshire   Dascombe MJ
Carr P
North SE
Ismail FMD An inhibitor of the sodium pump obtained from human placenta 1996 University of Hertfordshire   Hilton PJ
White RW
Lord GA
Haycox AR An integrated national pharmaceutical policy for the United Kingdom? 1998 University of Liverpool Prescribing Research Group Walley T
Earl-Slater A
Bagust A
MITCHESON J. An investigation of the role played by the E-4031-sensitive (rapid delayed rectifier) potassium current in isolated rabbit atrioventricular nodal and ventricular myocytes 1999 University of Leicester   Hancox J.C.
Perrett D Analysis of coricosteroids in biofluids by capillary electrochromatography with gradient elution. 1997 Queen Mary, University of London Pharmaceutical Bioanalysis Taylor MR
Teale P
Westwood SA
Edwardson J.M. Analysis of the association of syncollin with the membrane of the pancreatic zymogen granule. 2000 University of Cambridge   An, S.J.
Hansen, N.J.
Hodel, A.
STANDEN N.B. Angiotensin II inhibition of ATP-sensitive K+ currents in rat arterial smooth muscle cells through protein kinase C 1997 University of Leicester   Kubo, M.
Quayle, J.M.
Caulfield M J Angiotensinogen in human essential hypertension. 1996 Queen Mary, University of London Clinical Pharmacology Lavender P
Newell-Price J
Kamdar S
Jane DE Antagonist activity of a-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells. 1999 University of Bristol   Doherty,AJ
Collingridge,GL
Vane J Anti-inflammatory drugs and their mechanism of action. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Botting RM
La M Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase. 1998 Queen Mary, University of London Biochemical Pharmacology Bommel HM
Reif A
Frohlich LG
D'Cruz D Antibodies to beta2-glycoprotein I: a potential marker for clinical features of antiphospholipid antibody syndrome in patients with systemic lupus erythematosus. 1998 Queen Mary, University of London Bone and Joint Research Unit Sanfilippo SS
Khamashta MA
Atsumi T
Benjamin N Antimicrobial effect of acidified nitrite on gut pathogens: importance of dietary nitrate in host defense. 1996 Queen Mary, University of London Clinical Pharmacology Dykhuizen PS
Frazer R
Duncan C
Michel A.D. Apparent species differences in the kinetic properties of P2X7 receptors. 2000 University of Cambridge   Hibell, A.D.
Kidd, E.J.
Chessell, I.P.
Yaqoob M T Arachidonic acid protects against hypoxic injury in rat proximal tubules. 1996 Queen Mary, University of London Experimental Medicine and Nephrology Alkhunaizi AM
Edelstein CL
Gengaro PE
Kelly EP Arrestin isoforms dictate differential kinetics of A2B adenosine receptor trafficking. 2000 University of Bristol   Mundell,SJ
Matharu,A-L
Benovic,JL
Edwards IG Assessment of the effect of malaria infection on hepatic clearance of dihydroartemisinin using rat liver perfusions and microsomes 1998 University of Liverpool Tropical Pharmacology Batty KT
Ilett KF
Powell SM
Pirmohamed M Association analysis of drug metabolising enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole 2000 University of Liverpool Drug Safety Alfirevic A
Vilar J
Stalford A
Perretti M Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules. 2000 Queen Mary, University of London Biochemical Pharmacology McLean PG
Ahluwalia A
Mills P G Atrial fibrillation after coronary artery bypass surgery: a model for preoperative risk stratification. 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Zaman AG
Archbold RA
Helft G
POMPEO F Autophosphorylation of phosphoglucosamine mutase from Escherichia coli 2000 University of Oxford Pharmacogenetics + Toxicology Jolly, L.
van Heijenoort, J.
Fassy, F.
Skehel PA Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons 2000 University of Edinburgh Neural Plasticity Kaether C
Skehel P
Dotti CG
Ahluwalia A B1 receptors as a new inflammatory target. Could this B the 1?. 1999 Queen Mary, University of London Clinical Pharmacology Perretti
Forte P Basal nitric oxide synthesis in essential hypertension [see comments] 1997 Queen Mary, University of London Clinical Pharmacology Copland M
Smith LM
Milne E
Marston H Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat 1999 University of Edinburgh Neuropharmacology Marston HM
Reid ME
Lawrence JA
SEWARD E.P. Bidirectional modulation of exocytosis by angiotensin II involves multiple G-protein-regulated transduction pathways in chromaffin cells 2000 University of Leicester   Treschemacher A.G.
Seward EP Bidirectional modulation of exocytosis by angiotensin II involves multiple G-protein-regulated transduction pathways in chromaffin cells. 2000 University of Bristol   Teschemacher,AG
CAVIERES J.D. Binding of 2'(3')-O-(2,4,6- trinitrophenyl)ADP to soluble alphabeta protomers of Na,K-ATPase modified with fluorescein isothiocyanate - Evidence for two distinct nucleotide sites 1996 University of Leicester   Ward D.G.
Colquhoun D. Binding, gating, affinity and efficacy. The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. 1998 University College London Receptors, ion channels and transduction  
Bishop-Bailey D Bisphenol A diglycidyl ether (BADGE) is a PPARgamma agonist in an ECV304 cell line. 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Hla T
Warner TD
DAVIES N.W. Block of cloned BKCa channels (rSlo) expressed in HEK 293 cells by N-methyl D-glucamine 1998 University of Leicester   Lippiat, J.D.
Standen N.B.
Humphrey P.P.A. Blockade of human P2X7 receptor function with a monoclonal antibody. 1998 University of Cambridge   Buell, G.
Chessell, I.P.
Michel, A.D.
Rang H.P. Bradyzide, a potent non-peptide B(2) bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesia. 2000 University College London Neuropharmacology and neuroscience Burgess, G. M.
Perkins, M. N.
Campbell, E. A.
Dickenson A.H. Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors. 1998 University College London Neuropharmacology and neuroscience Bannon, A W
Decker, M. W.
Holladay, M. W.
Molleman A CB1 cannabinoid receptor-mediated activation of K+ current in DDT1 MF-2 cells is entirely dependent on the presence of extracellular Ca2+ 1999 University of Hertfordshire   Begg M
Nelemans SA
Willoughby D A COX-1, COX-2, and COX-3 and the future treatment of chronic inflammatory disease. 2000 Queen Mary, University of London Biochemical Pharmacology Moore AR
Colville-Nash PR
PATEL S Ca2+ -independent inhibition of inositol trisphosphate receptors by calmodulin: redistribtuion as a possible means of regulating Ca2+ mobilization 1997 University of Oxford Integrative Biology Morris, S.A.
Adkins, C.E.
O'Beirne, G.
Usowicz MM Ca2+ entry following store depletion in SH-SY5Y neuroblastoma cells 1996 University of Bristol   Grudt,TJ
Henderson,G
CAPOGNA M Ca2+ or Sr2+ partially rescues synaptic transmission in hippocampal cultures treated with botulinium toxin A and C, but not tetanus toxin 1997 University of Oxford Neuroscience McKinney, R.A.
O'Connor, V.
Gahwiler, B.H.
Taylor C.W. Ca2+-independent inhibition of inositol trisphosphate receptors by calmodulin: Redistribution of calmodulin as a possible means of regulating Ca2+ mobilization. 1997 University of Cambridge   Patel, S.
Morris, S.A.
Adkins, C.E.
Antoni FA Ca2+/calcineurin-inhibited adenylyl cyclase highly abundant in forebrain regions important for learning and memory 1998 University of Edinburgh Neural Plasticity Antoni FA
Palkovits M
Simpson J
Young J.M. Ca2+/calmodulin-mediated regulation of agonist-induced sequestration of Gq protein-coupled histamine H1-receptors in human U373 MG astrocytoma cells. 1998 University of Cambridge   Hishinuma, S.
Naiki, A.
Tsuga, H.
Genazzani A.A. Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons 1999 University of Cambridge   Carafoli, E.
Guerini, D.
Marrion NV Calcineurin regulates M-channel modal gating in sympathetic neurons. 1996 University of Bristol    
Dolphin A.C. Calcium channel beta subunit promotes voltage-dependent inhibition of alpha1B by G betagamma. 2000 University College London Neuropharmacology and neuroscience Meir, A.
Bell, D. C.
Stephens, G. J.
Brown D.A. Calcium channel gating and modulation by neurotransmitters depend on cellular compartmentalization. 2000 University College London Neuropharmacology and neuroscience Delmas, P.
Abogadie, F.C.
Buckley, N.J.
CAPOGNA M Calcium-independent actions of alpha-latrotoxin on spontaneous and evoked synaptic transmission in the hippocampus 1996 University of Oxford Neuroscience Gahwiler, B.H.
Thompson, S.M.
GABBOTT PLA Calretinin neurons in human medial prefrontal cortex (areas 24a,b,c, 32' and 25) 1996 University of Oxford Neuroscience Jays, P.R.
Bacon, S.J.
Rang H.P. Capsaicin and carbon dioxide act by distinct mechanisms on sensory nerve terminals in the cat cornea. 1997 University College London Neuropharmacology and neuroscience Chen, X.
Belmonte, C.
Kelly JS Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis 2000 University of Edinburgh Neuropharmacology Allsopp TE
McLuckie J
Kerr LE
Ferguson D.R. Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells. 2000 University of Cambridge   Michea, L.
Peters, E.M.
Andrews, P.M.
Gilroy D W Cell cycle dependent expression of cyclo-oxygenase 2 in human fibroblasts. 2000 Queen Mary, University of London Biochemical Pharmacology Saunders MA
Sansores-Garcia
Wu KK
NAGY Z Cell cycle markers in the hippocampus in Alzhemier's disease 1997 University of Oxford Neuroscience Esiri, M.M.
Cato, A.M.
Smith, A.D.
MCILHINNEY RAJ Cell surface expression of the human N-methyl-D-aspartate receptor subunit 1a requires the co-expression of the NR2A subunit in transfected cells 1996 University of Oxford Neuroscience Molnar, E.
Atack,J.R.
Whiting, P.J.
Kitteringham NR Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity 1999 University of Liverpool Drug Safety Hough SJ
Gill HJ
Pirmohamed M
Ward SA Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum 1999 University of Liverpool Tropical Pharmacology Bray PG
Janneh O
Raynes KJ
NAGY Z Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease 1999 University of Oxford Neuroscience Esiri, M.M.
Smith, M.Z.
Barnetson, L.
Kelly PAT Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats 1997 University of Edinburgh Neuropharmacology Fouyas IP
Kelly PAT
Ritchie IM
Kelly PAT Cerebrovascular responsiveness to NG-nitro-L-arginine methyl ester in spontaneously diabetic rats 1996 University of Edinburgh Neuropharmacology Fouyas IP
Kelly PAT
Ritchie IM
Barrand M.A. Changes in anion permeability following hypotonic challenge in rat brain endothelial cells: a comparison of responses in primary cultures and in immortalised RBE-4 cells. 1997 University of Cambridge   von Weikersthal, S.F.
Seetharaman, S.
Wright, K.A.
Donaldson IML Changes in dorsal neck muscle activity related to imposed eye movement in the decerebrate pigeon 1997 University of Edinburgh Neural Plasticity Hayman MR
Donaldson IML
Callingham B.A. Changes in reactivity of the digital artery of the fallow deer, Dama dama, in summer and winter. 1999 University of Cambridge   Milton, A.S.
Carr, G.
Luby, C.
Young J.M. Characateristics of the Ca2+-dependent inhibition of cyclic AMP accumulation by histamine and thapsigargin inhuman U373 MG astrocytoma cells. 2000 University of Cambridge   Wong, M.-P.W.
Cooper, D.M.F.
Young, K.W.
Kidd B L Characterisation of capsaicin-induced mechanical hyperalgesia as a marker for altered nociceptive processing in patients with rheumatoid arthritis. 1997 Queen Mary, University of London Bone and Joint Research Unit Cruwys SC
Morris VH
Antoni FA Characterisation of human adenylyl cyclase IX reveals inhibition by Ca2+/calcineurin and differential mRNA polyadenylation 2000 University of Edinburgh Neural Plasticity Paterson JM
Smith SM
Simpson J
FORSYTHE I.D. Characterisation of inhibitory and excitatory postsynaptic currents of the rat medial superior olive 2000 University of Leicester   Smith A.J.
Owens S.
Morton A.J. Characterisation of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. 1999 University of Cambridge   Carter, R.J.
Lione, L.A.
Humby, T.
GREENFIELD SA Characteristics of electrically evoked somatodendritic dopamine release in substantia nigra and ventral tegmental area in vitro 1997 University of Oxford Neuroscience Rice, M.E.
Cragg, S.J.
Larkman PM Characterization of 5-HT-sensitive potassium conductances in neonatal rat facial motoneurones in vitro 1998 University of Edinburgh Neuropharmacology Larkman PM
Kelly JS
GRUBB B.D. Characterization of cultured dorsal root ganglion neuron P2X receptors 1999 University of Leicester   Evans R.J
Feniuk W. Characterization of human recombinant somatostatin sst5 receptors mediating activation of phosphoinositide metabolism. 1997 University of Cambridge   Wilkinson, G.F.
Humphrey, P.P.A.
MCILHINNEY RAJ Characterization of the dimerization of metabotropic glutamate receptors using an N-terminal truncation of mGluR1 alpha 1999 University of Oxford Neuroscience Robbins, M.J.
Ciruela, F.
Rhodes, A.
BLANK J.L. Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase1 and MKK3/p38 pathways regulated by MEK Kinase 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo 1997 University of Leicester   Deacon, K.
Plane F Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. 1999 University of Bristol   Doughty,JM
Langton,PD
Winstanley PA Chlorproguanil-dapsone: an effective treatment for uncomplicated falciparum malaria. 1997 University of Liverpool Tropical Pharmacology Watkins W
Hatcher J
Lowe B
Kabouridis P Cholesterol depletion disrupts membrane rafts and modulates the activity of multiple signalling pathways in T cells. 2000 Queen Mary, University of London Bone and Joint Research Unit Janzen J
Magee AL
Ley SC
Ahluwalia A Cholinergic Contraction is Altered in nNOS Knockouts: Co-operative Modulation of Neural Bronchoconstriction by nNOS and COX 1999 Queen Mary, University of London Clinical Pharmacology Kakuyama M
Rodrigo J
Vallance P
PAULSEN OKH Cholinergic induction of network oscillations at 40Hz in the hippocampus in vitro 1998 University of Oxford Neuroscience Fisahn, A.
Pike, F.G.
Buhl, E.H.
Molleman A Chronic ethanol administration alters neuronal activity in VTA neurones after cessation of withdrawal hyperexcitability 1998 University of Hertfordshire   Bailey C P
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Timmis A D Circadian activity of the endogenous fibrinolytic system in stable coronary artery disease: effects of beta-adrenoreceptor blockers and angiotensin-converting enzyme inhibitors. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Sayer JW
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MacCallum P K Clinical characteristics determining the mode of presentation in patients with acute coronary syndromes. 1998 Queen Mary, University of London Experimental Therapeutics Kennon S
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Haycox AR Clinical guidelines 1999 University of Liverpool Prescribing Research Group Bagust A
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SIM E Cloning and characterisation of arylamine N-acetyltransferase genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: increased expression results in isoniazid resistance 1999 University of Oxford Pharmacogenetics + Toxicology Payton, M.
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PATEL S Co-ordination of Ca2+ signals by endothelial-derived nitric oxide in the intact liver 1999 University of Oxford Integrative Biology Robb Gaspers, L.D.
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GALIONE A Co-ordination of agonist-induced calcium signalling patterns by NAADP in pancreatic acinar cells 1999 University of Oxford Integrative Biology Cancela, J.M.
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Ribchester RR Co-regulation of synaptic efficacy at stable polyneuronally innervated neuromuscular junctions in reinnervated rat muscle 1999 University of Edinburgh Neural Plasticity Costanzo EM
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NAGY Z Coexisting pathologies in the brain: influence of vascular disease and Parkinson's disease on Alzheimer's pathology in the hippocampus 2000 University of Oxford Neuroscience Smith, M.Z.
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WATSON SP Collagen receptor signalling in platelets: extending the role of the ITAM 1998 University of Oxford Integrative Biology Gibbins, J.
Timmis A D Comparison of case fatality in south Asian and white patients after acute myocardial infarction: observational study [see comments] 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Wilkinson P
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Coker SJ Comparison of the acute cardiotoxicity of the antimalarial drug halofantrine in vitro and in vivo in anaesthetized guinea pigs 1997 University of Liverpool Tropical Pharmacology Batey AJ
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Molleman A Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption 1998 University of Hertfordshire   Bailey C P
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La M Comparison of the effects of hydroxocobalamin and oxyhaemoglobin on responses to NO, EDRF and the nitrergic transmitter. 1996 Queen Mary, University of London Biochemical Pharmacology Li CG
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Ribchester RR Competition at silent synapses in reinnervated skeletal muscle 2000 University of Edinburgh Neural Plasticity Costanzo EM
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CHALLISS R.A.J. Complex involvement of pertussis toxin-sensitive G-proteins in the regulation of type 1alpha metabotropic glutamate receptor signalling in BHK cells 2000 University of Leicester   Hermans E.
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Jenkinson D.H. Compounds that block both intermediate-conductance (IKCa) and small-conductance (SKCa) calcium-activated postassium channels. 2000 University College London Receptors, ion channels and transduction Malik-Hall, M.
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de Hoz L Contingent versus incidental context processing during conditioning: dissociation after excitotoxic hippocampal plus dentate gyrus lesions 1998 University of Edinburgh Neural Plasticity Good M
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FORSYTHE I.D. Contrasting Ca2+ channel subtypes at cell bodies and synaptic terminals of rat anterioventral cochlear bushy neurones 1998 University of Leicester   Doughty, J.M.
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Marrion NV Control of M-current. 1997 University of Bristol    
Taylor C.W. Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity. 1997 University of Cambridge   Marchant, J.S.
Richardson P.J. Correlating cell physiology with gene expression in single neurons 2000 University of Cambridge   Dixon, A.
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Haycox AR Cost-effectiveness of treatment for GORD in clinical practice 1998 University of Liverpool Prescribing Research Group Eggleston A
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TOBIN A.B. Cross-talk between m3-muscarinic and beta2-adrenergic receptors at the level of receptor phosphorylation and desensitisation 1999 University of Leicester   Budd D.C.
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POMPEO F Crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily 1999 University of Oxford Pharmacogenetics + Toxicology Brown, K.
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Foreman J.C. Cutaneous responses to endothelin-1 and histamine in patients with vibration white finger. 1998 University College London Receptors, ion channels and transduction Dowd, P. M.
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Vane J Cyclooxygenases 1 and 2. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Bakhle YS
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Colville-Nash P R Cyclopentenone prostaglandins-new allies in the war on inflammation [news] 2000 Queen Mary, University of London Biochemical Pharmacology Willoughby DA
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Matthews E.K. Cytotoxic, nuclear, and growth inhibitory effects of photodynamic drugs on pancreatic carcinoma cells. 1996 University of Cambridge   Ward, A.J.
Whittle B J Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobactor pylori: inhibition by superoxide dismutase. 2000 Queen Mary, University of London Experimental Therapeutics Moran AP
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Gergely F.V. D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo. 2000 University of Cambridge   Kidd, D.
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Sitsapesan RMA DIDS, DBDS and suramin cause similar modifications to cardiac ryanodine receptor function. 1999 University of Bristol    
PATEL S Decorin activates the epidermal growth factor receptor and elevates cytosolic Ca2+ in A431 carcinoma cells 1998 University of Oxford Integrative Biology Santra, M.
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Breckenridge AM Delta Steering Committee (A. Breckenridge, Chairman). Delta 1996 University of Liverpool Pharmacology of HIV Disease Aber V
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Waring M.J. Demethylation of thymine residues affects DNA cleavage by endonucleases but not sequence recognition by drugs. 1999 University of Cambridge   Bailly, C.
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Skehel PA Dendritic localization of mRNAs 1998 University of Edinburgh Neural Plasticity Kuhl D
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Brown D.A. Detection and modulation of acetylcholine release from neurites of rat cultured basal forebrain cells 1996 University College London Neuropharmacology and neuroscience Allen, T.G.J.
Finlayson K Detection of adenosine receptor antagonists in rat brain using a modified radioreceptor assay 1997 University of Edinburgh Neuropharmacology Finlayson K
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Perrett D Determination of taurine in plasma by capillary zone electrophoresis following derivatisation with fluorescamine [In Process Citation] 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Kelly MT
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Wall MJ Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum 1997 University of Bristol   Usowicz,MM
Usowicz MM Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum 1997 University of Bristol   Wall,MJ
Wall MJ Development of the quantal properties of evoked and spontaneous synaptic currents at a brain synapse 1998 University of Bristol   Usowicz,MM
Usowicz MM Development of the quantal properties of evoked and spontaneous synaptic currents at a brain synapse 1998 University of Bristol   Wall,MJ
MacIntyre I Developmental regulation of nitric oxide synthase expression in rat skeletal bone. 1999 Queen Mary, University of London Clinical Pharmacology Hukkanen MVJ
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Flower R J Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC. 1999 Queen Mary, University of London Biochemical Pharmacology Tailor A
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Stanford S.C. Differences in cenral noradrenergic and behavioural responses of Maudsley non-reactive and Maudsley reactive inbred rats on exposure to an aversive novel environment. 2000 University College London Neuropharmacology and neuroscience McQuade, R.
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Jenkinson D.H. Differences in the actions of some blockers of the calcium-activated potassium permeability in mammalian red cells. 1999 University College London Receptors, ion channels and transduction Benton, D. C. H.
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Marshall I. Different subtypes of alpha1A-adrenoceptor mediating contraction of rat epididymal vas deferens, rat hepatic portal vein and human prostate distinguished by the antagonist RS 17053 1996 University College London Receptors, ion channels and transduction Burt, R. P.
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Feniuk W. Differential agonist activity of somatostatin and L-362855 at human recombinant sst4 receptors. 1998 University of Cambridge   Smalley, K.S.M.
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GREENFIELD SA Differential autoreceptor control of somatodendritic and axon terminal dopamine release in substantia nigra, ventral tegmental area, and striatum 1997 University of Oxford Neuroscience Cragg, S.J.
Stocker M. Differential distribution of three Ca2+-activated K+ channel subunits SK1, SK2, and SK3 in the adult rat central nervous system. 2000 University College London Receptors, ion channels and transduction Pedarzani, P.
Fan T.P.D. Differential effects of angiostatic steroids and dexamethasone on angiogenesis and cytokine levels in rat sponge implants. 1996 University of Cambridge   Hori, Y.
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Gilroy D W Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation [see comments] 1998 Queen Mary, University of London Biochemical Pharmacology Tomlinson A
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Gilroy D W Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. 1998 Queen Mary, University of London Biochemical Pharmacology Tomlinson A
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Feniuk W. Differential effects of somatostatin and angiopeptin on cell proliferation. 1998 University of Cambridge   Alderton, F.
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Bishop-Bailey D Differential induction of cyclooxygenase-2 in human arterial and venous smooth muscle: role of endogenous prostanoids. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Pepper JR
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Usowicz MM Differential inhibition of Ca2+ channels in mature rat cerebellar Purkinje cells by sFTX-3.3 and FTX-3.3 1996 University of Bristol   Dupere,JRB
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Lobo M D Differential regulation of extracellular signal-regulated protein kinases (ERKs) 1 and 2 by cAMP and dissociation of ERK inhibition from anti-mitogenic effects in rabbit vascular smooth muscle cells. 1999 Queen Mary, University of London Clinical Pharmacology Cospedal R
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CHALLISS R.A.J. Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells 1998 University of Leicester   Willars, G.B
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Goyal M Differentiation of Mycobacterium tuberculosis Isolates by Spoligotyping and IS6110 Restriction Fragment Length Polymorphism 1997 University of Hertfordshire   Saunders NA
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DART C. Direct block of native and cloned (Kir2.1) inward rectifier K+ channels by chloroethylclonidine 1999 University of Leicester   Barrett-Jolley, R.
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Smith P.A. Direct effects of tolbutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic b-cells. 1999 University of Cambridge   Proks, P.
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Henderson R.M. Direct observation of DNA translocation and cleavage by the EcoKI endonuclease using atomic force microscopy. 1999 University of Cambridge   Ellis, D.J.
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Jenkinson D.H. Discrimination between subtypes of apamin-sensitive Ca 1996 University College London Receptors, ion channels and transduction Dunn, P. M.
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Naisbitt DJ Disposition of amodiaquine and related antimalarials in human neutrophils: Implications for drug design. 1997 University of Liverpool Drug Safety Ruscoe JE
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POMPEO F Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1-phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activity and 2000 University of Oxford Pharmacogenetics + Toxicology Bourne, Y.
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Morton A.J. Dopamine modulates the susceptibiity of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease. 1998 University of Cambridge   Reynolds, D.S.
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Arbuthnott GW Dopamine reverses the depression of rat cortico-striatal synapses which normally follows high frequency stimulation of cortex in vitro 1996 University of Edinburgh Neural Plasticity Wickens JR
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Sandin JSBE Dose- and time-dependent bimodal effects of k-opioid agonists on locomotor activity in mice 2000 University of Edinburgh Neural Plasticity Kuzmin A
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Arbuthnott GW Double anterograde tracing of outputs from adjacent barrel columns of rat somatosensory cortex. Neostriatal projection patterns and terminal ultrastructure 1999 University of Edinburgh Neural Plasticity Wright AK
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Young J.M. Dual effects of histamine and substance P on intracellular calcium levels in human U373 MG astrocytoma cells: role of protein kinase C. 1998 University of Cambridge   Young, K.W.
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Matthews E.K. Dynamics of actin measured by fluorescence correlation microscopy (FCM). 1996 University of Cambridge   Terry, B.R.
Venkateswarlu K EGF-and NGF-stimulated translocation of cytohesin-1 to the plasma membrane of PC12 cells requires PI 3-kinase activation and a functional cytohesin-1 PH domain. 1999 University of Bristol   Gunn-Moore,FJ
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Thiemermann C Effect of calpain inhibitor I, an inhibitor of the proteolysis of I kappa B, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat. 1997 Queen Mary, University of London Experimental Medicine and Nephrology Ruetten H
Born G V R Effect of captopril and losartan on blood pressure and accumulation of LDL and fibrinogen by aortic wall and other tissues in normotensive and hypertensive rats. 1997 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Medina R
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Born G V R Effect of deoxycorticosterone acetate on blood pressure in relation to accumulation of low-density lipoprotein and fibrinogen by aorta and other tissues of normotensive Wistar rats. 1997 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Medina RA
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Benjamin N Effect of nitric-oxide-generating system on microcirculatory blood flow in skin of patients with severe Raynaud's syndrome: a randomised trial. 1999 Queen Mary, University of London Clinical Pharmacology Tucker AT
Pearson RM
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Winstanley PA Effect of phenobarbital on seizure frequency and mortality in childhhood cerebral malaria 2000 University of Liverpool Tropical Pharmacology Crawley J
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Ramage A.G. Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats. 2000 University College London Neuropharmacology and neuroscience Wang, Y.
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Back DJ Effect of ribavirin on zidovudine efficacy and toxicity in vitro: A concentration dependent interaction 1998 University of Liverpool Pharmacology of HIV Disease Sim SM
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Kidd B L Effect of streptozotocin-diabetes on knee joint inflammation-induced changes in substance P and nerve growth factor in the rat. 1996 Queen Mary, University of London Bone and Joint Research Unit Garrett NE
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White R Effects of K+ channel openers on relaxations to nitric oxide and endothelium-derived hyperpolarizing factor in rat mesenteric artery. 1998 University of Cambridge   Hiley, C.R.
Coker SJ Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes 2000 University of Liverpool Tropical Pharmacology Batey AJ
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Arbuthnott GW Effects of potassium channel blockers on synaptic plasticity in the corticostriatal pathway 1998 University of Edinburgh Neural Plasticity Wickens JR
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La M Effects of pyrogallol, hydroquinone and duroquinone on responses to nitrergic nerve stimulation and NO in the rat anococcygeus muscle. 1999 Queen Mary, University of London Biochemical Pharmacology Rand MJ
Johnston A Effects of recombinent human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Comacho-Hubner C
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Born G V R Effects of reserpine on expression of LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo. 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Shafi S
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Zacharowski K Effects of the prostanoid EP3-receptor agonists M+B 28767 and GR 63799X on infarct size caused by regional myocardial ischaemia in the anaesthetized rat. 1999 Queen Mary, University of London Experimental Medicine and Nephrology Olbrich A
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Olverman HJ Effects of the specific serotonin reuptake inhibitor, citalopram upon local cerebral blood flow and glucose utilisation in the rat 1999 University of Edinburgh Neuropharmacology McBean DE
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Smith P.A. Electrogenic arginine transport mediates stimulus-secretion coupling in mouse pancreatic b-cells 1997 University of Cambridge   Sakura, H.
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Kozlowski RZ Electrophysiological consequences of purinergicreceptor stimulation in isolated rat pulmonary arterial myocytes. 1997 University of Bristol   Hartley,SA
Ribchester RR Elimination of motor nerve terminals in neonatal mice expressing a gene for slow Wallerian degeneration (C57Bl/Wlds) 1997 University of Edinburgh Neural Plasticity Parson SH
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Bishop-Bailey D Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Hla T
Carrier M J Endothelial dysfunction accompanies a pro-oxidant, pro-diabetic challenge in the insulin resistant, obese Zucker rat in vivo. 2000 Queen Mary, University of London Experimental Therapeutics Laight DW
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Corder R Endothelin-2 synthesis is stimulated by the type-1 tumour necrosis factor receptor and cAMP: comparison with endothelin-converting enzyme-1 expression. 2000 Queen Mary, University of London Experimental Therapeutics Lambert GL
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Hiley C.R. Endothelium and cannabinoid receptor involvement in levcromakalim vasorelaxation. 1997 University of Cambridge   White, R.
Zacharowski K Endotoxin induces a second window of protection in the rat heart as determined by using p-nitro-blue tetrazolium staining, cardiac troponin T release, and histology. 1999 Queen Mary, University of London Experimental Medicine and Nephrology Otto M
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Annenkov A E Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zeta [In Process Citation] 2000 Queen Mary, University of London Bone and Joint Research Unit Chernajovsky Y
Edwards IG Enhanced in vitro neurotoxicity of artemisinin derivatives in the presence of haem 1999 University of Liverpool Tropical Pharmacology Smith SL
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NAHORSKI S.R. Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors 1999 University of Leicester   Davis R.J.
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NAHORSKI S.R. Enhanced type 1alpha metabotropic glutamate receptor-stimulated phosphoinositide signalling after pertussis toxin treatment 1997 University of Leicester   Carruthers A.M.
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Ribchester RR Enhancement of spontaneous transmitter release at neonatal mouse neuromuscular junctions by the glial cell line derived neurotrophic factor (GDNF) 1998 University of Edinburgh Neural Plasticity Ribchester RR
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Caulfield M J Essential hypertension in African Caribbeans associates with a variant of the beta2-adrenoceptor. 1997 Queen Mary, University of London Clinical Pharmacology Kotanko P
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Caulfield M J Evaluation of the Angiotensinogen Locus in Human Essential Hypertension: A European Study. 1998 Queen Mary, University of London Clinical Pharmacology Brand E
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Anggard E Evaluation of the postprandial effects of a fast-food meal on human plasma F(2)-isoprostane levels. 2000 Queen Mary, University of London Experimental Therapeutics Gopaul NK
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Forte P Evidence for a difference in nitric oxide biosynthesis between healthy women and men. 1998 Queen Mary, University of London Clinical Pharmacology Kneale BJ
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Ramage A.G. Evidence for a role for central 5-HT2B as well as 5-HT2A receptors in cardiovascular regulation in anaesthetized rats. 1999 University College London Neuropharmacology and neuroscience Knowles, I. D.
Goulding N J Evidence for specific annexin I-binding proteins on human monocytes. 1996 Queen Mary, University of London Biochemical Pharmacology Pan L
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Poole AW Evidence of a role for SHP-1 in platelet activation by the collagen receptor glycoprotein VI. 2000 University of Bristol   Pasquet,J-M
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Willis D. Evidence that inducible cyclooxygenase may have anti-inflammatory properties. 1999 University College London Receptors, ion channels and transduction Gilroy, D.
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Grootveld M Examination of the metabolic status of rat air pouch inflammatory exudate by high field proton NMR spectroscopy. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Claxson A
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Fan T.P.D. Expression of angiogenic factor thymidine phosphorylase and angiogenesis in human atherosclerosis. 2000 University of Cambridge   Boyle, J.J.
Wilson, B.
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Kitteringham NR Expression of cytochrome P4502E1 in human liver: assessment by mRNA, genotype and phenotype 1998 University of Liverpool Drug Safety Powell H
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WATSON SP Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation 2000 University of Oxford Integrative Biology Berlanga, O.
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Richardson P.J. Expression profiling of single cells using three prime end amplification (TPEA) PCR. 1998 University of Cambridge   Dixon, A.
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Mills P G Extent of oxidative modification of low density lipoprotein determines the degree of cytotoxicity to human coronary artery cells. 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Thorne SA
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Anggard E F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease. 1999 Queen Mary, University of London Experimental Therapeutics Nourooz-Zadeh
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Nurrish S. Facilitation of synaptic transmission by EGL-30 Gqalpha and EGL-8 PlC beta: DAG binding to UNC-13 is required to stimulate acetylcholine release. 1999 University College London Neuropharmacology and neuroscience Lackner, M.R.
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Gibb A.J. Fast purinergic synaptic transmission in the central nervous system. 1996 University College London Neuropharmacology and neuroscience Halliday, F. C.
Koenig J.A. Fates of endocytosed somatostatin sst2 receptors and associated agonists. 1998 University of Cambridge   Kaur, R.
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Pitcher J.A. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. 1999 University College London Receptors, ion channels and transduction Tesmer, J. J.
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EMPTAGE NJ Fluorescent imaging of synaptic transmission at single synapses in the central nervous system 1999 University of Oxford Neuroscience Bliss, T.
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SMITH AD Folate, vitamin B12 and serum total homocysteine levels in confirmed Alzheimer's disease 1998 University of Oxford Neuroscience Clarke, R.
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Timmis A D Frequency and prognostic implications of conduction defects in acute myocardial infarction since the introduction of thrombolytic therapy. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Archbold RA
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Garthwaite J. Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway. 1997 University College London Neuropharmacology and neuroscience Batchelor, A. M.
Barrand M.A. Functional and molecular characterization of a volume-sensitive chloride current in rat brain endothelial cells. 1999 University of Cambridge   Weikersthal von, S.F.
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Kozlowski RZ Functional evidence for a novel suramin-insensitive pyrimidine receptor in rat small pulmonary arteries. 1998 University of Bristol   Hartley,SA
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MITCHESON J. Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel 2000 University of Leicester   Chen J.
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Pitcher J.A. G protein-coupled receptor kinases. 1998 University College London Receptors, ion channels and transduction Freedman, N. J.
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Moss S.J. GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton. 1999 University College London Receptors, ion channels and transduction Wang, H. W.
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Chernajovsky Y Gene therapy for chronic relapsing experimental allergic encephalomyelitis using cells expressing a novel soluble p75 dimeric TNF receptor. 2000 Queen Mary, University of London Bone and Joint Research Unit Croxford JL
Triantaphyllopoulos KA
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O'Byrne S Genetics of hypertension. Therapeutic implications. 1998 Queen Mary, University of London Clinical Pharmacology Caulfield M
Goyal M Genotypic analysis of Mycobacterium tuberculosis from medieval human remains 1999 University of Hertfordshire   Taylor GM
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Barakat K Getting to the heart of the matter. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Pyne D
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Croxtall J D Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism [In Process Citation] 2000 Queen Mary, University of London Biochemical Pharmacology Choudhury Q
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Kelly JS Glucocorticoids block protein kinase A inhibition of calcium-activated potassium channels 1996 University of Edinburgh Neuropharmacology Shipston MJ
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SOMOGYI P Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus 2000 University of Oxford Neuroscience Bergles, D.E.
Roberts, J.D.B.
Jahr, C.E.
Henderson G Glycine and GABAA receptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by 1998 University of Bristol   Grudt,TJ
Poole AW Glycoprotein GP Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor g-chain, Fyn and Lyn, to activate human platelets. 1999 University of Bristol   Falati,S
Edmead,CE
Roberts PJ Group I mGlu receptors potentiate synaptosomal [3H]glutamate release independently of exogenously applied arachidonic acid. 1999 University of Bristol   Reid,ME
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Benjamin N Helicobacter pylori is killed by nitrite under acidic conditions. 1998 Queen Mary, University of London Clinical Pharmacology Dykhuizen A
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Willoughby D A Heme oxygenase: a novel target for the modulation of the inflammatory response. 1996 Queen Mary, University of London Biochemical Pharmacology Willis D
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Willis D. Heme oxygenase: a novel target for the modulation of the inflammatory response. 1996 University College London Receptors, ion channels and transduction Moore, A.R.
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Park BK Hepatocellular response to chemical stress in CD-1 mice: Induction of early genes and g-glutamylcysteine synthetase 2000 University of Liverpool Drug Safety Kitteringham NR
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GREENFIELD SA Heterogeneity of electrically evoked dopamine release and reuptake in substantia nigra, ventral tegmental area and striatum 1997 University of Oxford Neuroscience Cragg, S.J.
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Stocker M. Heteromeric assembly of Kv9.3 with Kv2.1: Effect on the state-dependence of inactivation 1999 University College London Receptors, ion channels and transduction Kerschensteiner, D.
Sandin JSBE Hippocampal dynorphin B injections impair spatial learning in rats: A k-opioid receptor-mediated effect 1998 University of Edinburgh Neural Plasticity Sandin J
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Wood ER Hippocampal neurons encode information about different types of memory episodes occurring in the same location 2000 University of Edinburgh Neural Plasticity Wood ER
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Young J.M. Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]-g-aminobutyric acid release from depolarisation-stimulated slices of rat substantia nigra pars reticulata. 1997 University of Cambridge   Garcia, M.
Floran, B.
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Millar N.S. Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor alpha 7 subunit. 1997 University College London Receptors, ion channels and transduction Cooper, S. T.
Barakat K How should age affect management of acute myocardial infarction? A prospective cohort study [see comments] 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Wilkinson P
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Nissim A Human single-chain Fv fragments specific for natural killer cell receptors from phage display libraries. 2000 Queen Mary, University of London Bone and Joint Research Unit Uchanska-Ziegler B
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White R Human urotensin-II is an endothelium-dependent vasodilator in rat small arteries. 2000 University of Cambridge   Bottrill, F.E.
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Hiley C.R. Hyperpolarisation of rat mesenteric endothelial cells by ATP-sensitive K+ channel openers. 2000 University of Cambridge   White, R.
Moss G.W.J. Hypothesis for a serine proteinase-like domain at the COOH terminus of slowpoke calcium-activated potassium channels. 1996 University College London Receptors, ion channels and transduction Marshall, J.
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Hladky S.B. Hypotonicity-induced anion fluxes in cells expressing the multidrug resistance associated protein, MRP. 1996 University of Cambridge   Hainsworth, A.H.
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Barrand M.A. Hypotonicity-induced changes in anion permeability of cultured rat brain endothelial cells. 1996 University of Cambridge   von Weikersthal, S.F.
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Edwardson J.M. Identification of SNAREs involved in regulated exocytosis in the pancreatic acinar cell. 1999 University of Cambridge   Hansen, N.J.,
Antonin, W.
SANTORO B Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain 1998 University of Oxford Neuroscience Liu, D.T.
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NAHORSKI S.R. Identification of a novel receptor kinase that phosphorylates a phospholipase C-linked muscarinic receptor 1996 University of Leicester   Tobin A.B.
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Wyllie DJA Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors 1998 University of Edinburgh Neuropharmacology Anson LC
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Richardson P.J. Identification of an ATP sensitive potassium channel current in rat striatal cholinergic interneurones. 1998 University of Cambridge   Lee, K.
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Thiemermann C Identification of copper/zinc superoxide dismutase as a novel nitric oxide-regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats. 1999 Queen Mary, University of London Experimental Medicine and Nephrology Frank S
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Henderson R.M. Imaging ROMK1 inwardly rectifying ATP-sensitive K+ channel protein using atomic force microscopy. 1996 University of Cambridge   Schneider, S.
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Gould D J Immuno- and genetic therapy in autoimmune diseases. 2000 Queen Mary, University of London Bone and Joint Research Unit Chernajovsky Y
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McQueen DS Impaired cholinergic dilator response of resistance arteries isolated from patients with Raynauds disease 1999 University of Edinburgh Neuropharmacology Smith PJW
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Morris RGM Impaired spatial learning after saturation of long-term potentiation 1998 University of Edinburgh Neural Plasticity Moser EI
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PAULSEN OKH Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo 1998 University of Oxford Neuroscience Sprenge, R.
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Grant SGN Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo 1998 University of Edinburgh Neural Plasticity Sprengel R
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Grootveld M In vivo absorption, metabolism, and urinary excretion of alpha,beta-unsaturated aldehydes in experimental animals. Relevance to the development of cardiovascular diseases by the dietary ingestion of thermally stressed polyunsaturate-rich culinary oils. 1998 Queen Mary, University of London Pharmaceutical Bioanalysis Atherton MD
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FORSYTHE I.D. Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse 1998 University of Leicester   Tsujimoto T.
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Winyard P G Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite. 1996 Queen Mary, University of London Pharmaceutical Bioanalysis Frears ER
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Born G V R Increase by adrenaline or angiotensin II of the accumulation of low density lipoprotein and fibrinogen by aortic walls in unrestrained conscious rats. 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Cardona-Sanclemente LE
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Yaqoob M T Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy. 2000 Queen Mary, University of London Experimental Medicine and Nephrology Thuraisingham RC
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SOMOGYI P Increased number of synaptic GABA (A) receptors underlies potentiation at hippocampal inhibitory synapses 1998 University of Oxford Neuroscience Nusser, Z.
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Park BK Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi 2000 University of Liverpool Drug Safety Henderson CJ
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Gilroy D W Inducible cyclooxygenase may have anti-inflammatory properties [see comments] 1999 Queen Mary, University of London Biochemical Pharmacology Colville-Nash PR
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Mclean P G Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des-Arg9bradykinin-induced coronary vasodilation. 1999 Queen Mary, University of London Clinical Pharmacology Perretti M
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Vane J Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Simmons DL
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Bishop-Bailey D Induction of cyclooxygenase-2 in human saphenous vein and internal mammary artery. 1997 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Pepper JR
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Pirmohamed M Induction of metabolism-dependent and 1999 University of Liverpool Drug Safety Naisbitt DJ
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Ford W.R. Influence of b-adrenoceptor tone on the cardioprotective efficacy of adenosine A1 receptor acativation in isolated working rat hearts. 2000 University of Cambridge   Jugdutt, B.I.
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Walley TJ Influences of practice characteristics on prescribing in fundholding and non-fundholding general practices 1996 University of Liverpool Prescribing Research Group Wilson R
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Khoo SH Influenza-like episodes in HIV-positive patients: the role of viral and atypical infections 1998 University of Liverpool Pharmacology of HIV Disease Hajia M
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Roberts PJ Inhibition of AMPA receptor-stimulated 57Co2+ influx by D- and L-2-amino-4-phosphonobutanoic acid (L-AP4) and L-serine-O-phosphate (L-SOP) in cultured cerebellar granule cells 1997 University of Bristol   Toms,NJ
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Hoffman R Inhibition of Angiogenesis and murine tumour growth by laminarin sulphate 1996 University of Hertfordshire   Paper DH
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Yaqoob M T Inhibition of CFU-E colony formation in uremic patients with inflammatory disease: role of IFN-gamma and TNF-alpha [see comments] 1999 Queen Mary, University of London Experimental Medicine and Nephrology Allen DA
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CHALLISS R.A.J. Inhibition of N-linked glycosylation of the human type 1alpha metabotropic glutamate receptor by tunicamycin: effects on cell-surface expression and function 1999 University of Leicester   Mody N.
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Kabouridis P Inhibition of TCR/CD3-mediated signaling by a mutant of the hematopoietically expressed G16 GTP-binding protein. 1998 Queen Mary, University of London Bone and Joint Research Unit Zhou J
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Colville-Nash P R Inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: correlation with induction of heme oxygenase 1. 1998 Queen Mary, University of London Biochemical Pharmacology Qureshi SS
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Getting S J Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. 1997 Queen Mary, University of London Biochemical Pharmacology Flower RJ
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O'Byrne S Inhibition of platelet aggregation with glyceryl trinitrate and xanthine oxidoreductase. 2000 Queen Mary, University of London Clinical Pharmacology Shirodaria C
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Flower R J Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. 1997 Queen Mary, University of London Biochemical Pharmacology Szabo C
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Smith P.A. Inhibition of the ATP-sensitive potassium channel from mouse pancreatic b-cells by surfactants. 1998 University of Cambridge   Proks, P.
Thiemermann C Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle. 1997 Queen Mary, University of London Experimental Medicine and Nephrology Bowes J
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Foreman J.C. Inhibitors of nitric oxide synthase in human skin. 1996 University College London Receptors, ion channels and transduction Goldsmith, P. C.
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Chatterjee P K Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress. 1999 Queen Mary, University of London Experimental Medicine and Nephrology Cuzzocrea S
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Croxtall J D Inhibitory effect of peptides derived from the N-terminus of lipocortin 1 on arachidonic acid release and proliferation in the A549 cell line: identification of E-Q-E-Y-V as a crucial component. 1998 Queen Mary, University of London Biochemical Pharmacology Choudhury Q
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Callingham B.A. Inhibitory effects of glibenclamide on the contraction of human arterial conduits used in coronary artery bypass surgery 2000 University of Cambridge   Crosbie, A.E.
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Venkateswarlu K Insulin dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase. 1998 University of Bristol   Oatey,PB
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White R Interaction of cyclic AMP modulating agents with levcromakalim in the relaxation of rat isolated mesenteric artery. 2000 University of Cambridge   Omar, R.
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Back DJ Interaction of sildenafil and indinavir when co-administered to HIV-positive patients 1999 University of Liverpool Pharmacology of HIV Disease Merry C
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SANTORO B Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels 1997 University of Oxford Neuroscience Grant, S.G.N.
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Kitteringham NR Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene 1996 University of Liverpool Drug Safety Davis C
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Walley TJ Interpretation of data protection legislation - barriers to research 2000 University of Liverpool Prescribing Research Group Strobl J
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Pirmohamed M Intracellular glutathione in the peripheral blood cells of HIV-infected patients: failure to show a deficiency 1996 University of Liverpool Drug Safety Williams DP
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Moss S.J. Intracellular retention of recombinant GABAB receptors. 1998 University College London Receptors, ion channels and transduction Couve, A.
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Kelly PAT Intracerebral fetal raphe implants normalize hippocampal function but not cerebrovascular control in serotonin-depleted adult rat brain 1998 University of Edinburgh Neuropharmacology Kelly PAT
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Ford W.R. Intrinsic ANG II type 1 receptor stimulation contributes to recovery of postischemic mechanical function. 1998 University of Cambridge   Clanachan, A.S.
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Anggard E Investigation of endogenous nitric oxide vascular function in the carotid artery of cholesterol-fed rabbits. 1996 Queen Mary, University of London Experimental Therapeutics Laight D
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Carrier M J Investigation of oxidant stress and vasodepression to glyceryl trinitrate in the obese Zucker rat in vivo. 1998 Queen Mary, University of London Experimental Therapeutics Laight DW
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Berge T. Investigation of protein partnerships using atomic force microscopy. 1999 University of Cambridge   Ellis, D.J.
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Perretti M Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse. 1996 Queen Mary, University of London Biochemical Pharmacology Ahluwalia A
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Foreman J.C. Involvement of kinins in the hyperresponsiveness induced by platelet activating factor in the human nasal airway. 2000 University College London   Turner, P. J.
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Koenig J.A. Involvement of receptor cycling and receptor reserve in resensitization of muscarinic responses in SH-SY5Y human neuroblastoma cells. 1998 University of Cambridge   Szekeres, P.G.
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Michel A.D. Ionic effects on human recombinant P2X7 receptor function. 1999 University of Cambridge   Chessell, I.P.
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Ford W.R. K(ATP)-channel activation: Effects on myocardial recovery from ischaemia and role in the cardioprotective response to adenosine A1-receptor stimulation. 1998 University of Cambridge   Lopaschuk, G.D.
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CAVIERES J.D. K+ induces an acid-labile phosphoenzyme (or an occluded Pi form) in Na,K-ATPase 1997 University of Leicester   Buxbaum, E.
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DAVIES N.W. Kinetic analysis of the inhibitory effect of glibenclamide on KATP channels of mammalian skeletal muscle 1997 University of Leicester   Barrett-Jolley, R.
Genazzani A.A. Kinetic properties of Nicotinic Acid Adenine Dinucleotide Phosphate--induced Ca2+release. 1997 University of Cambridge   Mezna, M.
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Carter T.D. Kinetics of Ca2+ release by InsP3 in pig single aortic endothelial cells: evidence for an inhibitory role of cytosolic Ca2+ in regulating hormonally evoked Ca2+ spikes. 1997 University College London Receptors, ion channels and transduction Ogden, D.
Dolphin A.C. Known calcium channel alpha1 subunits can form low threshold small conductance channels with similarities to native T-type channels. 1998 University College London Neuropharmacology and neuroscience Meir, A.
ROEPER J Kv beta 1 subunit binding specific for Shaker-related potassium channel alpha subunits 1996 University of Oxford Neuroscience Sewing, S.
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WILLARS G.B. Lack of a C-terminal tail in the mammalian gonadotropin -releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization 1999 University of Leicester   Heding A.
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Taylor C.W. Lateral inhibition of inositol 1,4,5-trisphosphate receptors by cytosolic Ca2+. 1999 University of Cambridge   Adkins, C.E.
Walley TJ Lifestyle Medicines 2000 University of Liverpool Prescribing Research Group Gilbert D
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Flower R J Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. 1997 Queen Mary, University of London Biochemical Pharmacology Cuzzocrea S
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Annenkov A E Loss of original antigenic specificity in T cell hybridomas transduced with a chimeric receptor containing single-chain Fv of an anti-collagen antibody and Fc epsilonRI-signaling gamma subunit. 1998 Queen Mary, University of London Bone and Joint Research Unit Moyes SP
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D'Cruz D Lymphocyte activation markers and von Willebrand factor antigen in Wegener's granulomatosis: potential markers for disease activity. 1999 Queen Mary, University of London Bone and Joint Research Unit Direskeneli H
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NAHORSKI S.R. Lysophosphatidic acid-induced Ca2+ mobilisation requires intracellular sphingosine 1-phosphate production: potential involvement of endogenous Edg-4 receptors 2000 University of Leicester   Young K.W.
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BRUNSKILL N.J. Lysophosphatidic acid-induced calcium mobilization and proliferation in kidney proximal tubular cells 1999 University of Leicester   Dixon R.J.
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BRUNSKILL N.J. Lysophosphatidic acid-induced proliferation in opossum kidney proximal tubular cells: Role of PI 3-kinase and ERK 1999 University of Leicester   Dixon R.J.
BLANK J.L. MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases 1999 University of Leicester   Deacon, K.
Timmis A D Magnitude and consequences of error in coronary angiography interpretation (the ACRE study) [In Process Citation] 2000 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Banerjee S
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Fitzgerald E.M. Maintenance of the K+ activity gradient in insect muscle compared in Diptera and Lepidoptera: Contributions of metabolic and exchanger mechanisms. 1996 University College London Neuropharmacology and neuroscience Djamgoz, M. B. A.
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Park BK Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of a-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts 2000 University of Liverpool Drug Safety Boocock DJ
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SIM E Mapping AAC1, AAC2 and AACP, the genes for arylamine N-acetyltranferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours 1997 University of Oxford Pharmacogenetics + Toxicology Matas, N.
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Forte P Measurement of nitric oxide synthesis in humans using L-[15N2]arginine. 1999 Queen Mary, University of London Clinical Pharmacology Smith LM
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Johnston A Measurement of sirolimus in whole blood using high-performance liquid chromatography with ultraviolet detection. 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Lee T
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Ismail FMD Mechanism of formation of benzene-2-thiol 1998 University of Hertfordshire   Isaccs NS
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Thiemermann C Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ failure. 1998 Queen Mary, University of London Experimental Medicine and Nephrology Kengatharan KM
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STANDEN N.B. Mechanisms that regulate [Ca2+]i following depolarisation in rat systemic arterial smooth muscle cells 2000 University of Leicester   Kamishima, T.
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Carter T.D. Membrane capacitance changes induced by thrombin and calcium in single endothelial cells cultured from human umbilical vein. 1998 University College London Receptors, ion channels and transduction Zupancic, G.
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STANFIELD P.R. Membrane currents influencing action potential latency in granule neurons of the rat cochlear nucleus 1997 University of Leicester   Rusznak Z.
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Naisbitt DJ Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs 1998 University of Liverpool Drug Safety Williams DP
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Morton A.J. Mice transgenic for the Huntington's Disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity 2000 University of Cambridge   Hickey, M.A.
Thorn P. Microtubules regulate local Ca2+ spiking in secretory epithelial cells. 2000 University of Cambridge   Fogarty, K. E.
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CAPOGNA M Miniature synaptic events maintain dendritic spines via AMPA receptor activation 1999 University of Oxford Neuroscience McKinney, R A
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MacCallum P K Minimum effective intensity of oral anticoagulant therapy in primary prevention of coronary heart disease. 2000 Queen Mary, University of London Experimental Therapeutics Brennan PJ
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Perretti M Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. 1996 Queen Mary, University of London Biochemical Pharmacology Croxtall JD
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Mills P G Modified low density lipoprotein and cytokines mediate monocyte adhesion to smooth muscle cells. 1996 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Thorne SA
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Larkman PM Modulation of IH by 5-HT in neonatal rat motoneurones In Vitro: Mediation through a phosphorylation independent action of cAMP 1997 University of Edinburgh Neuropharmacology Larkman PM
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Back DJ Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. 1999 University of Liverpool Pharmacology of HIV Disease Profit L
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Sandin JSBE Modulation of acetylcholine and serotonin transmission by galanin 1998 University of Edinburgh Neural Plasticity Ogren SO
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Yaqoob M T Modulation of hypoxia-induced calpain activity in rat proximal tubules. 1996 Queen Mary, University of London Experimental Medicine and Nephrology Edelstein CL
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Stanford S.C. Modulation of sibutramine-induced increases in extracellular noradrenaline concentration in rat frontal cortex and hypothalamus by alpha2-adrenoceptors. 1999 University College London Neuropharmacology and neuroscience Wortley, K.E.
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Thomas P. Modulation of stimulus-secretion coupling in single rat gonadotrophs. 1997 University of Cambridge   Waring, D.W.
MacIntyre I Modulation of the effects of Osteoprotegerin (OPG) Ligand in Human Leukemic Cell Line by OPG and Calcitonin. 2000 Queen Mary, University of London Clinical Pharmacology Mancini L
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Jacobs M. Modulation of vascular tone by low density lipoproteins: effects on L-arginine transport and nitric oxide synthesis. 1997 University College London Receptors, ion channels and transduction Jay, M.T.
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MCILHINNEY RAJ Molecular characterization of two structurally distinct groups of human Homers, generated by extensive alternative splicing 2000 University of Oxford Neuroscience Soloviev, M.M.
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Barnard E.A. Molecular cloning and characterisation of the rat P2Y4 receptor. 1998 University of Cambridge   Webb, T.E.
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BLANK J.L. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase 1996 University of Leicester   Gerwins, P.
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Antoni FA Molecular components of large conductance calcium-activated potassium (BK) channels in mouse pituitary corticostropes 1999 University of Edinburgh Neural Plasticity Shipston MJ
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Murrell-Lagnado R.D. Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channels. 1997 University of Cambridge   Woodward, R.
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Murrell-Lagnado R.D. Molecular determinants for sodium-dependent activation of G protein-gated K+ channels. 1999 University of Cambridge   Ho, I.H.M.
Getting S J Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. 1997 Queen Mary, University of London Biochemical Pharmacology Flower RJ
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Antoni FA Molecular diversity of cyclic AMP signalling 2000 University of Edinburgh Neural Plasticity Antoni FA
Winstanley PA Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum 2000 University of Liverpool Tropical Pharmacology Nzila AM
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Callingham B.A. Monoamine oxidase activities in human cystic and colonic arteries - influence of age. 1998 University of Cambridge   Figueiredo, I.V.
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Skehel PA Mouse VAP33 is associated with the endoplasmic reticulum and microtubules 2000 University of Edinburgh Neural Plasticity Skehel PA
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MacCallum P K Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. 1998 Queen Mary, University of London Experimental Therapeutics Poller L
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Grootveld M Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: the roles of endogenous pyruvate and lactate. Relevance to inflammatory joint diseases. 1997 Queen Mary, University of London Pharmaceutical Bioanalysis Herz H
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van Veen H.W. Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane. 1996 University of Cambridge   Bolhuis, H.
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Thorn P. Multiple, coordinated Ca2+-release events underlie the inositol trisphosphate-induced local Ca2+ spikes in mouse pancreatic acinar cells. 1996 University of Cambridge   Moreton, R.
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Dunn SMJ Mutagenesis of the rat a1 subunit of the ?-aminobutyric acid receptor reveals the importance of residue 101 in determining the allosteric effects of benzodiazepine site ligands. 1999 University of Bristol   Davies,M
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Chernajovsky Y Mutation of proline 211 reduces shedding of the human p75 TNF receptor. 1998 Queen Mary, University of London Bone and Joint Research Unit Herman C
Munroe P B Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome. 1999 Queen Mary, University of London Clinical Pharmacology Olgunturk RO
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Munroe P B Mutations in the palmitoyl-protein thioesterase gene (PPT; CLN1) causing juvenile neuronal ceroid lipofuscinosis with granular osmiophilic deposits [published erratum appears in Hum Mol Genet 1998 Apr;7(4):765] 1998 Queen Mary, University of London Clinical Pharmacology Mitchison HM
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Schoepfer R. Mutiple structural elements determine subunit-specificity of Mg2+ block in NMDA receptor channels. 1996 University College London Receptors, ion channels and transduction Kuner, T.
MCILHINNEY RAJ Myristoylation does not modulate the properties of MARCKS-related protein (MRP) in solution 1996 University of Oxford Neuroscience Schleiff, E.
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ROEPER J NIP domain prevents N-type inactivation in voltage-gated potassium channels 1998 University of Oxford Neuroscience Sewing, S.
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Jane DE Native NMDA receptors containing NR2A and NR2B subunits have pharmacologically-distinct competitive antagonist binding sites. 2000 University of Bristol   Christie,JM
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Getting S J Natural and synthetic agonists of the melanocortin receptor type 3 possess anti inflammatory properties. 2000 Queen Mary, University of London Biochemical Pharmacology Allcock GH
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PAULSEN OKH Natural patterns of activity and long-tem synaptic plasticity 2000 University of Oxford Neuroscience Sejnowski, T.J.
Sharkey J Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism 1997 University of Edinburgh Neuropharmacology Butcher SP
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Wood ER Neurotoxic hippocampal lesions have no effect on odor span and little effect on odor recognition memory but produce significant impairments on spatial span, recognition, and alternation 2000 University of Edinburgh Neural Plasticity Dudchenko PA
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Johnston A New approaches to Cyclosporine monitoring raise further concerns about analytical techniques. 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Holt DW
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Sharkey J New use of a macrolide compound 2000 University of Edinburgh Neuropharmacology Jones P
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Kelly JS New use of aminopiperazine derivatives 1998 University of Edinburgh Neuropharmacology Marston HM
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Genazzani A.A. Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive pool 1996 University of Cambridge   Galione, A
Coleman JW Nitric oxide inhibits IgE-mediated degranulation of mast cellsand is the principal intermediate in IFN-g-induced suppression of exocytosis 1997 University of Liverpool Drug Safety Eastmond NC
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Plane F Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery 1997 University of Bristol   Cohen,RA
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MacIntyre I Nitric oxide superoxide and peroxynitrite modulate osteoclast activity. 1998 Queen Mary, University of London Clinical Pharmacology Mancini L
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O'Byrne S Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion. 2000 Queen Mary, University of London Clinical Pharmacology Forte P
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Forte P Nitric oxide synthesis in patients with infective gastroenteritis. 1999 Queen Mary, University of London Clinical Pharmacology Dykhuizen RS
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GALIONE A Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway 1996 University of Oxford Integrative Biology Willmott, N.J.
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Sandin JSBE Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats 1997 University of Edinburgh Neural Plasticity Sandin J
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Harmar AJ Nomenclature of Receptors for Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide 1998 University of Edinburgh Neuropharmacology Harmar AJ
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Warner T D Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis [published erratum appears in Proc Natl Acad Sci U S A 1999 Aug 17;96(17):9666] 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Giuliano F
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Ismail FMD Novel aryl-bis-quinolones with antimalarial activity in vivo 1998 University of Hertfordshire   Dascombe MJ
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Goulding N J Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. 1998 Queen Mary, University of London Biochemical Pharmacology Euzger HS
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Perrett D Novel three-dimensional capillary electrophoresis system for complex and trace analyis. 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Hanna M
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Rang H.P. Noxious heat activates all capsaicin-sensitive and also a sub-population of capsaicin-insensitive dorsal root ganglion neurons. 1999 University College London Neuropharmacology and neuroscience Nagy, I.
Lobo M D Nuclear localization and apoptotic regulation of an amino-terminal. 2000 Queen Mary, University of London Clinical Pharmacology Zachary I
Irvine R.F. Nuclear targeting of the B isoform of Type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its a-helix 7. 2000 University of Cambridge   Ciruela, A.
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Irvine R.F. Nuclei contain two differentially regulated pools of diacylglycerol. 1999 University of Cambridge   D'Santos, C.
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Ford W.R. Opposite effects of angiotensin AT1 and AT2 receptor antagonists on recovery of mechanical function after ischemia-reperfusion in isolated working rat hearts. 1996 University of Cambridge   Clanachan, A.S.
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Perrett D Optimised separation of endogenous urinary components using cyclodextrin-modified micellar electrokinetic capillary chromatography [In Process Citation] 2000 Queen Mary, University of London Pharmaceutical Bioanalysis Alfazema LN
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CAPOGNA M Organotypic slice cultures: a technique has come of age 1996 University of Oxford Neuroscience Gahwiler, B.H.
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Shen S Overexpression of the human VPAC2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice 2000 University of Edinburgh Neuropharmacology Shen S
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Marston H Overexpression of the human VPAC2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice 2000 University of Edinburgh Neuropharmacology Shen S
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Jacobs M. Oxidized low-density lipoproteins inhibit endothelium-dependent relaxations in isolated large and small rabbit coronary arteries. 1996 University College London Receptors, ion channels and transduction Buckley, C.
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EVANS R.J. P2 receptor mediated control of rat cerebral (pial) microvasculature; contribution of P2X and P2Y receptors 2000 University of Leicester   Lewis C.J.
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McQueen DS P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint 1998 University of Edinburgh Neuropharmacology Dowd E
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SEWARD E.P. P2Y purinoceptors inhibit exocytosis in adrenal chromaffin cells via modulation of voltage-operated calcium channels 2000 University of Leicester   Powell A.D.
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Seward EP P2Y purinoceptors inhibit exocytosis in adrenal chromaffin cells via modulation of voltage-operated calcium channels. 2000 University of Bristol   Powell,AD
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Hinchliffe K.A. PIPkins, their substrates and their products; new functions for old enzymes. 1998 University of Cambridge   Ciruela, A.
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Getting S J POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. 1999 Queen Mary, University of London Biochemical Pharmacology Gibbs L
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Taylor C.W. Parathyroid hormone controls the size of the intracellular Ca2+ stores available to receptors linked to inositol trisphosphate formation. 2000 University of Cambridge   Short, A.D.
Berge T. Patterned regrowth of n-GaAs by molecular beam epitaxy using arsenic passivation 1999 University of Cambridge   Heinlen, C.
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Breckenridge AM Pharmacokinetics of combination therapy with nelfinavir plus nevirapine. 1998 University of Liverpool Pharmacology of HIV Disease Merry C
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Jane DE Pharmacological agents acting at subtypes of metabotropic glutamate receptors. 1999 University of Bristol   Schoepp,DD
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EMPTAGE NJ Pharmacological and kinetic characterization of two functional classes of serotonergic modulation in Aplysia sensory neurons 1996 University of Oxford Neuroscience Stark, L.L.
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Olverman HJ Pharmacological characterisation of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques 1998 University of Edinburgh Neuropharmacology Marston HM
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Marshall I. Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. 1998 University College London Receptors, ion channels and transduction Wisskirchen, F. M.
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Marston H Pharmacological characterization of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques 1998 University of Edinburgh Neuropharmacology Marston HM
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Finlayson K Pharmacological characterization of a simple behavioral response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques 1998 University of Edinburgh Neuropharmacology Marston HM
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Jane DE Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. 1998 University of Bristol   Thomas,NK
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WATSON SP Phosphatidylinositol 3,4,5-trisphosphate regulates Ca2+ entry via Btk in platelets and megakaryocytes without increasing phospholipase C activity 2000 University of Oxford Integrative Biology Pasquet, J-M.
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Pitcher J.A. Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies. 1996 University College London Receptors, ion channels and transduction Fredericks, Z. L.
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TOBIN A.B. Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha 2000 University of Leicester   Budd D.C.
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CAVIERES J.D. Photoinactivation of fluorescein isothiocyanate-modified Na,K-ATPase by 2'(3')-0-(2,4,6-trinitrophenyl)8-azidoadenosine 5'-diphosphate. Abolition of E1 and E2 partial reactions by sequential block of high and low-affinity nucleotide sites 1998 University of Leicester   Ward, D.G.
Anggard E Photoplethysmographic assessment of pulse wave reflection: blunted response to endothelium-dependent beta2-adrenergic vasodilation in type II diabetes mellitus. 1999 Queen Mary, University of London Experimental Therapeutics Chowienczyk PJ
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Ward SA Physicochemical properties correlated with drug resistance and its reversal in Plasmodium falciparum 1996 University of Liverpool Tropical Pharmacology Bray PG
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WILLARS G.B. Pivotal role for the cytoplasmic carboxyl-terminal tail of a nonmammalian gonadotropin-releasing hormone receptor in cell surface expression, ligand binding, and receptor phosphorylation and internalization 1999 University of Leicester   Blomenroehr, M.
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Naisbitt DJ Plasma cysteine deficiency and decreased reduction of nitrosulfamethoxazole with HIV infection 2000 University of Liverpool Drug Safety Vilar FJ
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Benjamin N Plasma nitrate concentration in infective gastroenteritis and inflammatory bowel disease. 1996 Queen Mary, University of London Clinical Pharmacology Dykhuizen RS
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Arbuthnott GW Plasticity of striatopallidal terminals following unilateral lesion of the dopaminergic nigrostriatal pathway: A morphological study 1997 University of Edinburgh Neural Plasticity Ingham CA
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Barakat K Platelet IIb/IIIa antagonists followed by delayed stent implantation. A new treatment for vein graft lesions containing massive thrombus. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Robinson N
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Harmar AJ Polymorphism in serotonin transporter gene associated with susceptibility to major depression 1996 University of Edinburgh Neuropharmacology Ogilvie AD
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Carter T.D. Potency and kinetics of nitric oxide-mediated vascular smooth muscle relaxation determined with flash photolysis of ruthenium nitrosyl chlorides. 1997 University College London Receptors, ion channels and transduction Bettache, N.
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Coker SJ Potential interactions between iloprost and SIN-1 on platelet aggregation and myocardial infarct size 1999 University of Liverpool Tropical Pharmacology Aitchison KA
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FORSYTHE I.D. Presynaptic calcium current modulation by a metabotropic glutamate receptor 1996 University of Leicester   Takahashi, T.
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Carrier M J Pro-oxidant challenge in vivo provokes the onset of NIDDM in the insulin resistant obese Zucker rat. 1999 Queen Mary, University of London Experimental Therapeutics Laight DW
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POMPEO F Probing the role of cysteine residues in glucosamine-1-phosphate acetyltransferase activity of the bifunctional GlmU protein from Escherichia coli: site-directed mutagenesis and characterization of the mutant enzymes 1998 University of Oxford Pharmacogenetics + Toxicology van Heijenoort, J.
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Sellers L.A. Prolonged activation of extracellular signal-regulated kinase by a protein kinase C-dependent and N17Ras-insensitive mechanism mediates the proliferative response of Gi/o-coupled somatostatin sst4 receptors. 1999 University of Cambridge    
Perretti M Promoting detachment of neurophils adherent to murine post-capillary venules to control inflammation: Effect of lipocortin 1. 1998 Queen Mary, University of London Biochemical Pharmacology Lim LHK
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GRUBB B.D. Prostanoids synthesised by cyclooxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability 1997 University of Leicester   Willingale, H.L.
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Chan W L Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium. 1998 Queen Mary, University of London Bone and Joint Research Unit Xu D
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Grant SGN Proteomic analysis of NMDA receptor-adhesion protein signaling complexes 2000 University of Edinburgh Neural Plasticity Husi H
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Stanford S.C. Prozac: panacea or puzzle? 1996 University College London Neuropharmacology and neuroscience  
Goyal M Pulmonary tuberculosis in Harare, Zimbabwe: analysis by spoligotyping 1998 University of Hertfordshire   Heyderman RS
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Breckenridge AM Quattro Steering Committee (A. Breckenridge, Chairman). A randomised trial comparing regimens of four reverse transcriptase inhibitors given together or cyclically in HIV-1 Infection 1999 University of Liverpool Pharmacology of HIV Disease Babiker A
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Waring M.J. Quinaxaline antibiotics enhance peptide nucleic acid binding to double-stranded DNA. 2000 University of Cambridge   Mollegaard, N.E.
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Michel A.D. Radiolabeling of the rat P2X4 purinoceptor: evidence for allosteric interactions of purinoceptor antagonists and monovalent cations with P2X purinoceptors. 1997 University of Cambridge   Miller, K.J.
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Garthwaite J. Rapid desensitization of the nitric oxide receptor, soluble guanylyl cyclase, underlies diversity of cellular cGMP responses. 2000 University College London Neuropharmacology and neuroscience Bellamy, T.C.
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Molleman A Reactive oxygen species generation by non-immunological mast cell activation: modulation by the synthetic cannabinoid CP55,940 1999 University of Hertfordshire   Brooks A C
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BRUNSKILL N.J. Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase 1998 University of Leicester   Stuart J.
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Naisbitt DJ Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals. 2000 University of Liverpool Drug Safety Schnyder B
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Chernajovsky Y Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis. 1999 Queen Mary, University of London Bone and Joint Research Unit Rabinovitch G
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Schoepfer R. Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel. behaviour. 1997 University College London Receptors, ion channels and transduction Sivilotti, L. G.
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Sharkey J Recommendations for standards regarding preclinical neuroprotective and restorative drug development 1999 University of Edinburgh Neuropharmacology Finklestein SP
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Zacharowski K Reduction of myocardial infarct size with sCR1sLe(x), an alternatively glycosylated form of human soluble complement receptor type 1 (sCR1), possessing sialyl Lewis x. 1999 Queen Mary, University of London Experimental Medicine and Nephrology Otto M
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Shen S Refined mapping of the human serotonin transporter (SLC6A4) gene within 17q11 adjacent to the CPD and NF1 genes 2000 University of Edinburgh Neuropharmacology Shen S
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Warner T D Regulation of Cyclo-oxygenase Gene Expression in Rat Smooth Muscle Cells by Catalase. 1998 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Chen G
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Hinchliffe K.A. Regulation of PtdIns 4-P 5-kinase C by thrombin-stimulated changes in its phosphorylation state in human platelets. 1998 University of Cambridge   Irvine, R.F.
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BLANK J.L. Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G protein-linked muscarine acetylcholine receptors 1999 University of Leicester   Wylie P.G.
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Hinchliffe K.A. Regulation of type IIa phosphatidylinositol phosphate kinase localisation by the protein kinase CK2. 1999 University of Cambridge   Ciruela, A.
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BOLAM PB Relationship of activity in the subthalamic nucleus-globus pallidus network to cortical electroencephalogram 2000 University of Oxford Neuroscience Magill, P.J.
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Kozlowski RZ Relaxation of endothelin-1 induced pulmonary arterial constriction by niflumic acid and NPPB: mechanism(s) independent of chloride channel block. 1999 University of Bristol   Kato,K
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de Hoz L Reversible neural inactivation reveals hippocampal participation in several memory processes 1999 University of Edinburgh Neural Plasticity Riedel G
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Kabouridis P S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. 1997 Queen Mary, University of London Bone and Joint Research Unit Magee AI
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Breckenridge AM Saquinavir kinetics alone and in combination with ritonavir in HIV infected patients 1997 University of Liverpool Pharmacology of HIV Disease Merry C
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Nissim A Screening of phage antibody libraries. 1996 Queen Mary, University of London Bone and Joint Research Unit Harrison JL
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McQueen DS Secretoneurin: a novel carotid body peptide 1996 University of Edinburgh Neuropharmacology McQueen DS
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Marrion NV Selective activation of calcium-activated potassium channels by colocalized calcium channels in hippocampal neurons 1998 University of Bristol   Tavalin,SJ
Zacharowski K Selective activation of the prostaglanoid EP(3) receptor reduces myocardial infarct size in rodents 1999 Queen Mary, University of London Experimental Medicine and Nephrology Olbrich A
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Chan W L Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. 1998 Queen Mary, University of London Bone and Joint Research Unit Xu D
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Kelly EP Selective reduction in A2 adenosine receptor desensitization following antisense-induced suppression of G protein-coupled receptor kinase 2 expression. 1999 University of Bristol   Willets,JM
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Feniuk W. Selective somatostatin sst2 receptor blockade with the novel cyclic octapeptide, CYN-154806. 2000 University of Cambridge   Jarvie, E.
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Fan T.P.D. Sequential development of angiotensin receptors and angiotensin converting enzyme during angiogenesis in the rat subcutaneous sponge granuloma. 1997 University of Cambridge   Walsh, D.A.
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Nurrish S. Serotonin inhibition of synaptic transmission: Galpha0 decreases the abundance of UNC-13 at release sites. 1999 University College London Neuropharmacology and neuroscience Segalat, L.
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MacCallum P K Sex differences in the determinants of fibrinolytic activity. 1998 Queen Mary, University of London Experimental Therapeutics Cooper JA
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Venkateswarlu K Signalling via ARF6 lies downstream of PI 3-kinase. 2000 University of Bristol   Cullen,PJ
Donaldson IML Signals of eye position and velocity in the first-order afferents from pigeon extraocular muscles 1998 University of Edinburgh Neural Plasticity Fahy FL
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Rang H.P. Similarities and differences between the responses of rat sensory neurons to noxious heat and capsaicin. 1999 University College London Neuropharmacology and neuroscience Nagy, I.
Winyard P G Simultaneous analysis of nitrite, nitrate and the nicotinamide nucleotides by capillary electrophoresis: application to biochemical studies and human extracellular fluids. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Davies CA
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EMPTAGE NJ Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines 1999 University of Oxford Neuroscience Bliss, T.V.P.
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Wyllie DJA Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors 1998 University of Edinburgh Neuropharmacology Wyllie DJA
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Schoepfer R. Single-channel analysis of a NMDA receptor possessing a mutation in the region of the glutamate binding site. 2000 University College London Receptors, ion channels and transduction Anson, L. C.
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Cull-Candy S.G. Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition. 1997 University College London Neuropharmacology and neuroscience Swanson, G. T.
Kamboj, S. K.
Wyllie DJA Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells 2000 University of Edinburgh Neuropharmacology Misra C
Brickley SG
Wyllie DJA
BRADING AF Smooth muscle of the bladder in the normal and the diseased state: pathophysiology, diagnosis and treatment 1997 University of Oxford Integrative Biology Turner, W.H.
Annenkov A E Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritis. 2000 Queen Mary, University of London Bone and Joint Research Unit Dreja H
Chernajovsky Y
Kelly EP Somatostatin receptor desensitization in NG108-15 cells: a consequence of receptor sequestration? 1998 University of Bristol   Beaumont,VL
Hepworth,MB
Luty,JS
Henderson G Somatostatin receptor desensitization in NG108-15 cells: a consequence of receptor sequestration? 1998 University of Bristol   Beaumont,VL
Hepworth,MB
Luty,JS
Koenig J.A. Somatostatin receptors in Neuro2A neuroblastoma cells: ligand internalization. 1997 University of Cambridge   Edwardson, J.M.
Humphrey, P.P.A.
Koenig J.A. Somatostatin receptors in Neuro2A neuroblastoma cells: operational characteristics. 1997 University of Cambridge   Edwardson, J.M.
Humphrey, P.P.A.
Sellers L.A. Somatostatin sst5 inhibition of receptor mediated regeneration of rat aortic vascular smooth muscle cells. 1997 University of Cambridge   Lauder, H.
Fan, T.-P.D.
Feniuk, W.
Humphrey P.P.A. Somatostatin5 receptor-mediated [35S]Guanosine-5'-0-(3-thio)triphosphate binding: agonist potencies and the influence of sodium chloride on intrinsic activity. 1997 University of Cambridge   Williams, A .J.
Michel, A.D.
Feniuk, W.
CHURCHILL GC Spatial control of calcium signaling by NAADP diffusion and gradients 2000 University of Oxford Integrative Biology Galione, A.
Olverman HJ Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists 1997 University of Edinburgh Neuropharmacology Maemoto T
Finlayson K
Olverman HJ
Finlayson K Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists 1997 University of Edinburgh Neuropharmacology Maemoto T
Finlayson K
Olverman HJ
Nissim A Specific inhibition of the reaction between a tumor-inhibitory antibody and Erb-2 receptor by a mimotype derived from a phage display library. 2000 Queen Mary, University of London Bone and Joint Research Unit Vaisman N
Klapper LN
Tirosh B
McNaughton P.A. Specific involvement of PKC-e in sensitization of the neuronal response to painful heat. 1999 University of Cambridge   Cesare, P.
Dekker, L.V.
Sardini, A.
Munroe P B Spectrum of mutations in the Batten disease gene, CLN3. 1997 Queen Mary, University of London Clinical Pharmacology Mitchison HM
O'Rawe AM
Anderson JW
Goyal M Spoligotyping in Molecular epidemiology of Tuberculosis in Ghana 1999 University of Hertfordshire   Lawn SD
Afful B
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CHALLISS R.A.J. Stable overexpression of the type-1 inositol 1,4,5-trisphosphate receptor in L fibroblasts: subcellular distribution and functional consequences 1996 University of Leicester   Mackrill J.J.
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TOBIN A.B. Stimulus-Dependent Phosphorylation of G-Protein Coupled Receptors By Casein Kinase 1alpha 1997 University of Leicester   Totty N.F.
Sterlin A.E.
Nahorski S.R.
Hladky S.B. Streaming potentials in gramicidin channels measured with ion selective microelectrodes. 1998 University of Cambridge   Tripathi, S.
Henderson R.M. Structural activity of a cloned potassium channel (ROMK1) monitored with the atomic force microscope: the molecular-sandwich technique. 1997 University of Cambridge   Oberleithner, H.
Schneider, S.W.
BRADING AF Structural and functional denervation of human detrusor after spinal cord injury 2000 University of Oxford Integrative Biology Drake, M.J.
Hedlund, F.
Mills, I.W.
Sitsapesan RMA Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor. 2000 University of Bristol   Chan,WM
Welch,W
SIM E Structure of arylamine N-acetyltransferase reveals a catalytic triad 2000 University of Oxford Pharmacogenetics + Toxicology Sinclair, J.C.
Sandy, J.
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Shen S Structure of the human VIPR2 gene for vasoactive intestinal peptide receptor type 2 1999 University of Edinburgh Neuropharmacology Lutz EM
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Moss G.W.J. Structure-activity relationships for the interaction of bovine pancreatic trypsin inhibitor with an intracellular site on a large conductance Ca 2000 University College London Receptors, ion channels and transduction Favre, I.
Goldenberg, D.P.
Otlewski, J.
Corder R Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. 1999 Queen Mary, University of London Experimental Therapeutics Barker DM
Moss S.J. Subcellular localisation of gamma-aminobutyric acid type A receptors is determined by receptor beta subunits. 1996 University College London Receptors, ion channels and transduction Connolly, C. N.
Wooltorton, J. A.
Smart, T. G.
Stocker M. Subunit assembly and domain analysis of electrically silent K+ channel alpha-subunits of the rat Kv9 subfamily. 1999 University College London Receptors, ion channels and transduction Hellwig, M.
Kerschensteiner, D.
Sihra T.S. Synapsins as mediators of BDNF-enhanced neurotransmitter release. 2000 University College London Neuropharmacology and neuroscience Jovanovic, J. N.
Czernik, A. J.
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Cull-Candy S.G. Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype. 2000 University College London Neuropharmacology and neuroscience Liu, S. Q.
Martin SJ Synaptic plasticity and memory: an evaluation of the hypothesis 2000 University of Edinburgh Neural Plasticity Martin SJ
Grimwood P D
Morris RGM
Morris RGM Synaptic tagging and long term potentiation 1997 University of Edinburgh Neural Plasticity Frey U
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Warner T D Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: consequences for nonsteroidal antiinflammatory drug efficacy. 1999 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Hamilton LC
Mitchell JA
Tomlinson AM
SMITH AD Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease 1997 University of Oxford Neuroscience Lehmann, D.J.
Johnston, C.
Edwards IG Synthesis and antimalarial activity of sixteen dispiro-1,2,4,5-tetroxane analogs of WR 148999 1998 University of Liverpool Tropical Pharmacology Vennerstrom J
Dong Y
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Hoffman R Synthesis of sulphated acrylic polymers and their evaluation as inhibitors of basic fibroblast growth factor dependent cell growth 2000 University of Hertfordshire   Adnett JB
Hay JN
Niederst C
Jenkinson D.H. Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca 2000 University College London Receptors, ion channels and transduction Campos Rosa. J.
Galanakis, D.
Piergentili, A.
Marston H Tacrolimus (FK506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats 1996 University of Edinburgh Neuropharmacology Sharkey J
Crawford JH
Butcher SP
Croxtall J D Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A549 cells. 1997 Queen Mary, University of London Biochemical Pharmacology Choudhury Q
White JO
Flower RJ
SOMOGYI P Target-cell specific concentration of a metabotropic glutamate receptor in the presynaptic active zone 1996 University of Oxford Neuroscience Shigemoto, R.
Kulik, A.
Roberts, J.D.
Nissim A Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform. 1997 Queen Mary, University of London Bone and Joint Research Unit Neri D
Carnemolla B
Leprini A
Chatterjee P K Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. 2000 Queen Mary, University of London Experimental Medicine and Nephrology Cuzzocrea S
Brown PA
Zacharowski K
Thomas P. Tetrabutylammonium: a selective blocker of the somatostatin-activated hyperpolarizing current in mouse AtT-20 corticotrophs. 2000 University of Cambridge   Smith, P.
van Veen H.W. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. 2000 University of Cambridge   Margolles, A.
Muller, M.
Higgins, C.F.
Poole AW The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen 1997 University of Bristol   Gibbins,JM
Turner,M
Van Vugt,MJ
Pitcher J.A. The G protein-coupled receptor kinase is a microtubule-associated protein kinase that phosphorylates tubulin. 1998 University College London Receptors, ion channels and transduction Hall, R. A.
Daaka, Y.
Zhang, J.
Walley TJ The General Practice Research Database 1999 University of Liverpool Prescribing Research Group Mantgani A
SANTORO B The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels 1999 University of Oxford Neuroscience Tibbs, G.R.
Thomas P. The LbT2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion. 1996 University of Cambridge   Mellon, P.L.
Turgeon, J.L.
Waring, D.W.
Venkateswarlu K The N-terminal membrane domain of yeast NADPH-cytochrome P450 Oxidoreductase is not required for catalytic activity in sterol biosynthesis or in reconstitution of CYP activity. 1998 University of Bristol   Lamb,DC
Kelly,DE
Kelly,SL
Haycox AR The North Staffordshire Community beds study 1999 University of Liverpool Prescribing Research Group Unsworth L
Allen K
Hodgson R
Barnard E.A. The P2Y purinoceptor in rat brain microvascular endothelial cells couples to inhibition of adenylate cyclase. 1996 University of Cambridge   Webb, T.E.
Feolde, F.
Vigne, P.
Barnard E.A. The P2Y1 receptor closes the N-type Ca2+ channel in neurones, with both adenosine trisphosphates and diphosphates as potent agonists. 2000 University of Cambridge   Filippov, A.K.
Brown, D.A.
Gergely F.V. The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. 2000 University of Cambridge   Karlsson, C.
Still, I.
Cowell, J.
Hiley C.R. The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. 1998 University of Cambridge   White, R.
White R The actions of the cannabinoid receptor antagonist, SR141716A, in the rat isolated mesenteric artery. 1998 University of Cambridge   Hiley, C.R.
Brown D.A. The alpha subunit of Gq contributes to muscarinic inhibition of the M-type potassium current in sympathetic neurons. 1998 University College London Neuropharmacology and neuroscience Haley, J.E.
Abogadie, F.C.
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Annenkov A E The beta 2 integrin Mac-1 but not p150,95 associates with Fc gamma RIIA. 1996 Queen Mary, University of London Bone and Joint Research Unit Ortlepp S
Hogg N
Edwards IG The biliary metabolites of b-artemether, an endoperoxide antimalarial 1997 University of Liverpool Tropical Pharmacology Maggs JL
Bishop LPD
O'Neill PM
MacIntyre I The biphasic effects of nitric oxide in primary rat osteoblasts are cGMP dependent. 2000 Queen Mary, University of London Clinical Pharmacology Mancini L
Moradi-Bidhendi N
Becherini L
Ramage A.G. The central action of the 5-HT2 receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cardiac inotropy and vascular resistance in the anaesthetized cat. 1998 University College London Neuropharmacology and neuroscience Daly, M. de B.
Willoughby D A The codependence of angiogenesis and chronic inflammation. 1997 Queen Mary, University of London Biochemical Pharmacology Jackson JR
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Croxtall J D The concerted regulation of cPLA2, COX2, and lipocortin 1 expression by IL-1beta in A549 cells. 1996 Queen Mary, University of London Biochemical Pharmacology Newman SP
Choudhury Q
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Corder R The conformation of human big endothelin-1 favours endopeptidase hydrolysis of the TRP21-VAL22 bond. 1996 Queen Mary, University of London Experimental Therapeutics  
DART C. The dependence of Ag+-block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter 1998 University of Leicester   Leyland, M.L.
Barrett-Jolley, R.A.
Shelton P.A.
Colville-Nash P R The depletion of substance P by diclofenac in the mouse. 1997 Queen Mary, University of London Biochemical Pharmacology Papworth J
Alam C
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Pirmohamed M The effect of the CYP2C9 genetic polymorphisms on sulphamethoxazole N-hydroxylation 1999 University of Liverpool Drug Safety Gill HJ
Kitteringham NR
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Roberts PJ The effects of (RS)-a-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist 1996 University of Bristol   Toms,NJ
Jane,DE
Kemp,MC
NAGY Z The effects of additional pathology on the cognitive deficit in Alzheimer's disease 1997 University of Oxford Neuroscience Esiri, M.M.
Jobst, K.A.
Morris, J.H.
Waring M.J. The exocyclic groups of DNA modulate the affinity and positioning of the histone octamer. 1998 University of Cambridge   Buttinelli, M.
Minnock, A.
Panetta, G.
Corder R The expression of endothelin-1 and endothelin-converting enzyme-1 are independently regulated in bovine aortic endothelial cells. 1999 Queen Mary, University of London Experimental Therapeutics Barker S
Morris RGM The functional neuroanatomy of comprehension and memory: the importance of prior knowledge 1999 University of Edinburgh Neural Plasticity Maguire EA
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Donaldson IML The functions of the proprioceptors of the eye muscles 2000 University of Edinburgh Neural Plasticity Donaldson IML
Wood ER The global record of memory in hippocampal neuronal activity 1999 University of Edinburgh Neural Plasticity Wood ER
Dudchenko PA
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Wood ER The hippocampus, memory, and place cells: Is it spatial memory or a memory space? 1999 University of Edinburgh Neural Plasticity Eichenbaum H
Dudchenko PA
Wood ER
Willoughby D A The inhibition of colon-26 adenocarcinoma development and angiogenesis by topical diclofenac in 2.5% hyaluronan. 1997 Queen Mary, University of London Biochemical Pharmacology Seed MP
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Freemantle CN
Goulding N J The inhibitory effect of dexamethasone on lymphocyte adhesion molecule expression and intercellular aggregation is not mediated by lipocortin 1. 1999 Queen Mary, University of London Biochemical Pharmacology Ogbourn S
Pipitone N
Biagini P
Khoo SH The integrin-triggered rescue of T lymphocyte apoptosis is blocked in HIV-1 infected individuals 1997 University of Liverpool Pharmacology of HIV Disease Ng TTC
Kanner SB
Humphries MJ
GRUBB B.D. The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an upregulation of cyclooxygenase-2 in the spinal cord 1999 University of Leicester   Ebersberger A.
Willingale H.L.
Gardiner N.J.
Millar N.S. The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. 1997 University College London Receptors, ion channels and transduction Lewis, T. M.
Harkness, P. C.
Sivilotti, L. G.
Gergely F.V. The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila. 1997 University of Cambridge   Micklem, D.R.
Dasgupta, R.
Elliott, H.
COLEMAN MP The major brain isoform of Kif1b lacks the putative mitochondria-binding domain 1999 University of Oxford Neuroscience Conforti, L.
Buckmaster, E.A.
Tarlton, A.
Jacobs M. The nitration of platelet cytosolic proteins during agonist-induced activation of platelets. 2000 University College London Receptors, ion channels and transduction Naseem, K.M.
Low, S.Y.
Sabetkar, M.
NICOTERA PL The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown 1997 University of Leicester   Gohring, F.
Schwab, B.L.
Leist, M.
Back DJ The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1. 1999 University of Liverpool Pharmacology of HIV Disease Moore KHP
Barrett JE
Shaw S
STANFIELD P.R. The possible role of disulphiode bond in forming functional Kir2.1 potassium channels 1999 University of Leicester   Leyland, M.L.
Dart C.
Spencer P.J.
Hemming K The preparation of 4-substituted pyrilium salts and their use in dienal synthesis 1996 University of Hertfordshire   Charoenying P
McKerrecher D
Taylor RJK
DART C. The properties and distribution of inward rectifier potassium currents in pig coronary arterial smooth muscle 1996 University of Leicester   Quayle, J.M.
Standen N.B.
Moss S.J. The protein MAP-IB links GABAC receptors to the cytoskeleton at retinal synapses. 1999 University College London Receptors, ion channels and transduction Hanley, J. G.
Koulen, P.
Bedford, F. K.
Edwardson J.M. The relationship between agonist intrinsic activity and the rate of endocytosis of muscarinic receptors in a human neuroblastoma cell line. 1998 University of Cambridge   Szekeres, P.G.
Koenig, J.A.
Kitteringham NR The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat 1997 University of Liverpool Drug Safety Gill HJ
Hough SJ
Naisbitt DJ
Thorn P. The role of Ca2+ feedback in shaping InsP3-evoked Ca2+ signals in mouse pancreatic acinar cells. 1999 University of Cambridge   Kidd, J.F.
Fogarty, K.E.
Tuft, R.A.
Grootveld M The role of N-acetylcysteine in protecting synovial fluid biomolecules against radiolytically-mediated oxidative damage: a high field proton NMR study. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Silwood CJ
Lynch EJ
Patel IY
Marshall I. The role of diacylglycerol and activation of protein kinase C in the alpha 1A-adrenoceptor-mediated contraction to noradrenaline of the rat isolated epididymal vas deferens. 1996 University College London Receptors, ion channels and transduction Burt, R. P.
Chapple, C. R.
Kabouridis P The role of lipid rafts in T cell antigen receptor (TCR) signalling. 2000 Queen Mary, University of London Bone and Joint Research Unit Janes PW
Ley SC
Magee AI
EVANS R.J. The role of positively charged amino acids in ATP recognition by human P2X1 receptors 2000 University of Leicester   Ennion S.
Hagan S.
Foreman J.C. The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells. 1999 University College London Receptors, ion channels and transduction Tatla, S.
Woodhead, V.
Chain, B. M.
Mills P G The role of signal averaged P wave duration and serum magnesium as a combined predictor of atrial fibrillation after elective coronary artery bypass surgery. 1997 Queen Mary, University of London Cardiac, Vascular and Inflammation Research Zaman AG
Alamgir F
Richens T
Colville-Nash P R The role of vascular endothelial growth factor in a murine chronic granulomatous tissue air pouch model of angiogenesis. 1996 Queen Mary, University of London Biochemical Pharmacology Appleton I
Brown NJ
Willis D
Edwardson J.M. The secretory granule protein syncollin binds to syntaxin in a Ca2+-sensitive manner. 1997 University of Cambridge   An, S.
Jahn, R.
DART C. The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis 1998 University of Leicester   Leyland, M.L.
Spencer P.J.
Stanfield P.R.
Dickenson A.H. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. 1999 University College London Neuropharmacology and neuroscience Akopian, A N.
Souslova, V.
England, S.
Hoffman R The use of proteases as prognostic markers for the healing of venous leg ulcers 1999 University of Hertfordshire   Noble J
Eagle M
ROEPER J The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels 1999 University of Oxford Neuroscience Liss, B.
Neu, A.
Johnston A Therapeutic drug monitoring of immunosuppressant drugs. 1999 Queen Mary, University of London Pharmaceutical Bioanalysis Holt DW
EMPTAGE NJ Threshold serotonin concentration required to produce synaptic facilitation differs for depressed and nondepressed synapses in Aplysia sensory neurons 1996 University of Oxford Neuroscience Mauelshagen, J.
Carew, T.J.
Hinchliffe K.A. Thrombin stimulation of platelets causes an increase in phosphatidylinositol 5-phosphate revealed by mass assay. 2000 University of Cambridge   Morris, J.B.
Ciruela, A.
Letcher, A.
Poole AW Thrombin-induced association of SHP-2 with multiple tyrosine-phosphorylated proteins in human platelets. 1999 University of Bristol   Edmead,CE
Crosby,D
Southcott,MJG
Winstanley PA Towards an understanding of the mechanism of pyrimethamine- sulfadoxine resistance in Plasmodium falciparum: the genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. 2000 University of Liverpool Tropical Pharmacology N'zila A
Sibley C
Mberu E
NICOTERA PL Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity 1999 University of Leicester   Hansson, O
Petersen, A
Leist, M
Berge T. Translocation-independent dimerization of the EcoK1 endonuclease visualized by atomic force microscopy. 2000 University of Cambridge   Ellis, D.J.
Dryden, D.T.
Edwardson, J.M.
MITCHESON J. Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate 2000 University of Leicester   Chen J.
Sanguinetti M.C.
Khoo SH Tumour Necrosis Factor c2 microsatellite allele is associated with the rate of HIV disease progression 1997 University of Liverpool Pharmacology of HIV Disease Ollier WER
Hajeer A
Snowden N
Coleman JW Tumour necrosis factor-a expression and cell recruitment in Sephadex particle-induced lung inflammation: effects of dexamethasone and cyclosporin A 1997 University of Liverpool Drug Safety Williams CMM
Smith L
Flanagan BF
GALIONE A Two neuropeptides recruit different messenger pathways to envoke Ca2+ signals in the same cell 2000 University of Oxford Integrative Biology Burdakov, D.
Brown D.A. Two types of K+ channel subunit, Erg1 and KCNQ2/3, contribute to the M-like current in a mammalian neuronal cell. 1999 University College London Neuropharmacology and neuroscience Selyanko, A.A.
Hadley, J.K.
Wood, I.C.
Dunn SMJ Tyrosine 62 of the ?-aminobutyric acid type A receptor 2000 University of Bristol   Newell,JG
Davies,M
Bateson,AN
Garthwaite J. Tyrosine kinase is required for long term depression in the cerebellum. 1996 University College London Neuropharmacology and neuroscience Boxall, A.
Lancaster, B.
Dickenson A.H. Unaltered peripheral excitatory actions of nociceptin contrast with enhanced spinal inhibitory effects after carrageenan inflammation: an electrophysiological study in the rat. 2000 University College London Neuropharmacology and neuroscience Carpenter, K
Vithlani, M.
Genazzani A.A. Unique inactivation properties of NAADP-sensitive Ca2+ release 1996 University of Cambridge   Empson, R.M.
Galione, A.
PATEL S Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhances the sensitivity of NAADP receptors for their ligand 2000 University of Oxford Integrative Biology Churchill, G.C.
Galione, A.
Millar N.S. Upregulation of cell-surface alpha4beta2 neuronal nicotinic receptors by lower temperature and expression of chimeric subunits. 1999 University College London Receptors, ion channels and transduction Cooper, S . T.
Harkness, P. C.
Baker, E. R.
Ferguson D.R. Urothelial function. 1999 University of Cambridge    
Hladky S.B. Use of membrane vesicles to investigate drug interactions with transporter proteins, P-glycoprotein and multidrug resistance-associated protein. 2000 University of Cambridge   Wheeler, R.
Neo, S.-Y.
Chew, J.
SMITH AD Use of structural imaging to study the progression of Alzheimer's disease 1996 University of Oxford Neuroscience Jobst, K.A.
Shen S Vectors and YACs comprising an IRES 1999 University of Edinburgh Neuropharmacology Shen S
Schedl A
Harmar AJ
Garthwaite J. Vicious cycle involving Na+ channels, glutamate release and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation. 1996 University College London Neuropharmacology and neuroscience Strijbos, P. J. L. M.
Leach, M. J.
Dickenson A.H. Warm coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. 2000 University College London Neuropharmacology and neuroscience Souslova, V.
Cesare, P.
Ding, Y.
SHARP T Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate in the brain 2000 University of Oxford Neuroscience Patel, S.
Churchill, G.C.
Galione, A.
Hoffman R Wound fluid from venous leg ulcers degrades plasminogen and reduces plasmin generation by keratinocytes 1998 University of Hertfordshire   Starkey S
Coad J
Barnard E.A. Xenopus oocytes express a unitary glutamate receptor endogenously. 1997 University of Cambridge   Soloviev, M.M.
Fitzgerald E.M. cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS. 1999 University College London Neuropharmacology and neuroscience Okuse, K.
Wood, J. N.
Dolphin, A. C.
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